Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wai Ling Cheung-Lee"'
Autor:
Christopher K. Prier, Karla Camacho Soto, Jacob H. Forstater, Nadine Kuhl, Jeffrey T. Kuethe, Wai Ling Cheung-Lee, Michael J. Di Maso, Claire M. Eberle, Shane T. Grosser, Hsing-I Ho, Erik Hoyt, Anne Maguire, Kevin M. Maloney, Amanda Makarewicz, Jonathan P. McMullen, Jeffrey C. Moore, Grant S. Murphy, Karthik Narsimhan, Weilan Pan, Nelo R. Rivera, Anumita Saha-Shah, David A. Thaisrivongs, Deeptak Verma, Adeya Wyatt, Daniel Zewge
Publikováno v:
ACS Catalysis. :7707-7714
Enzymes are capable of unique and selective transformations that can enable sustainable chemical production. While many industrial processes have been developed using free enzymes in aqueous solutions, immobilizing enzymes on a solid support can offe
Autor:
Hader E. Elashal, Joseph D. Koos, Wai Ling Cheung-Lee, Brian Choi, Li Cao, Michelle A. Richardson, Heather L. White, A. James Link
Publikováno v:
Nat Chem
Microviridins and other ω-ester-linked peptides, collectively known as graspetides, are characterized by side-chain-side-chain linkages installed by ATP-grasp enzymes. Here we report the discovery of a family of graspetides, the gene clusters of whi
Autor:
Madison E. Parry, Alexis Jaramillo Cartagena, Wai Ling Cheung-Lee, A. James Link, Riccardo Russo, Chuhan Zong, Nancy Connell, Seth A. Darst
Publikováno v:
Chembiochem
We report the heterologous expression, structure, and antimicrobial activity of a lasso peptide, ubonodin, encoded in the genome of Burkholderia ubonensis. The topology of ubonodin is unprecedented amongst lasso peptides, with 18 of its 28 amino acid
Autor:
Joseph D. Koos, Brian Choi, Michelle A. Richardson, Heather L. White, A. James Link, Hader E. Elashal, Li Cao, Wai Ling Cheung-Lee
Microviridins and other ω−ester linked peptides (OEPs) are characterized by sidechain-sidechain linkages installed by ATP-grasp enzymes. Here we describe the discovery of a new family of OEPs, the gene clusters of which also encode an O-methyltran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d97ce54816d022746991ac673218a34e
https://doi.org/10.1101/2021.05.19.444834
https://doi.org/10.1101/2021.05.19.444834
Publikováno v:
ACS Chem Biol
Lasso peptides are a family of ribosomally synthesized and post-translationally modified peptides (RiPPs) defined by their threaded-ring topology. The N-terminus of the peptide forms an isopeptide bond with an aspartate or glutamate side chain to cre
Publikováno v:
Chemical Communications. 54:1339-1342
We describe a lasso peptide, albusnodin, that is post-translationally modified with an acetyl group, the first example of a lasso peptide with this modification. Using heterologous expression, we further show that the acetyltransferase colocalized wi
Autor:
A. James Link, Wai Ling Cheung-Lee
Publikováno v:
J Ind Microbiol Biotechnol
Over the course of roughly a decade, the lasso peptide field has been transformed. Whereas new compounds were discovered infrequently via activity-driven approaches, now, the vast majority of lasso peptide discovery is driven by genome-mining approac
Autor:
Seth A. Darst, Alexis Jaramillo Cartagena, Madison E. Parry, A. James Link, Wai Ling Cheung-Lee
We report the identification of citrocin, a 19-amino acid-long antimicrobial lasso peptide from the bacteria Citrobacter pasteurii and Citrobacter braakii. We refactored the citrocin gene cluster and heterologously expressed it in Escherichia coli. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c8790c69c975f2b8c709e3647b57bb
https://europepmc.org/articles/PMC6497930/
https://europepmc.org/articles/PMC6497930/