Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Wai Kiong Ng"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1141 (2021)
Artemether, an artemisinin derivative, is used in the management of life-threatening severe malaria. This study aimed to develop an intravenous dosage form of artemether using nanotechnology. Artemether-loaded zein nanoparticles were prepared by modi
Externí odkaz:
https://doaj.org/article/027ae1e996134db9a3a86cc1a816928a
Publikováno v:
Pharmaceutics, Vol 10, Iss 1, p 35 (2018)
In order to improve the aqueous solubility and dissolution of Tacrolimus (TAC), amorphous solid dispersions of TAC were prepared by hot melt extrusion with three hydrophilic polymers, Polyvinylpyrrolidone vinyl acetate (PVP VA64), Soluplus® and Hydr
Externí odkaz:
https://doaj.org/article/4e4b95ba75e04134bc97162979b87731
Autor:
Choon Keong Lee, Shipin Zhang, Gopalakrishnan Venkatesan, null Irsan, Suet Yen Chong, Jiong-Wei Wang, Wei Jiang Goh, Tomasz Panczyk, Yi Zhen Tay, Jun Hu, Wai Kiong Ng, Matthias G. Wacker, Wei Seong Toh, Giorgia Pastorin
Publikováno v:
Biomaterials science. 10(7)
Dermal delivery of bioactive molecules remains an attractive route of administration in osteoarthritis (OA) due to the local accumulation of drugs while avoiding their systemic side effects. In this study we propose a proniosome gel comprising non-io
Publikováno v:
Current Drug Delivery. 16:663-671
Background: Sirolimus (SIR) is a macrocyclic lactone antibiotic and used therapeutically as a potent immunosuppressant for prophylaxis of kidney transplant rejection. The development of an oral dosage form is challenging because of very poor aqueous
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1141, p 1141 (2021)
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1141, p 1141 (2021)
Artemether, an artemisinin derivative, is used in the management of life-threatening severe malaria. This study aimed to develop an intravenous dosage form of artemether using nanotechnology. Artemether-loaded zein nanoparticles were prepared by modi
Publikováno v:
Advanced Powder Technology. 29:957-963
The aim of this study is to investigate the feasibility of producing pharmaceutical nanoformulations for enhanced oral or pulmonary delivery of poorly water-soluble drugs via liquid antisolvent precipitation followed by immediate (on-line) spray dryi
Intravenous human serum albumin (HSA)-bound artemether nanoparticles for treatment of severe malaria
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 536:20-29
Severe malaria is potentially life-threatening and requires the parenteral administration of the artemisinin-based formulation for short duration of action. Intravenous artemether formulation has shown potentially better therapeutic efficacy but its
Autor:
Shoucang Shen, Reginald B. H. Tan, Wai Kiong Ng, Wilson Wang, Poddar Kingshuk, Kumaran Letchmanan, Zhilong Shi
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 72:163-170
The influence of mesoporous silica nanoparticles (MSNs) loaded with antibiotics on the mechanical properties of functional poly(methyl methacrylate)-(PMMA) based bone cements is investigated. The incorporation of MSNs to the bone cements (8.15 wt%) s
Publikováno v:
Crystal Growth & Design. 17:4064-4071
Despite the rising interest in pharmaceutical cocrystals in the past decade, there is a lack of research on the solid processing of cocrystals downstream to crystallization. Mechanical stress induced by unit operations such as milling could affect th
Publikováno v:
Advanced Powder Technology. 28:1316-1324
To improve the dissolution properties of poorly water soluble active pharmaceutical ingredients (APIs), a solvent-free melt-absorption process was applied to directly load the APIs into mesoporous SBA-15 silica powder as an amorphous solid dispersion