Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Waheeda Sirah"'
Autor:
Anders G. Olsson, Fabian Chen, Christine McCrary Sisk, Waheeda Sirah, Darbie Maccubbin, Yale B. Mitchel, Harold E. Bays, Jennifer W. Anderson, Uma Kher
Publikováno v:
The American Journal of Cardiology. 110:817-822
Extended-release niacin (ERN) improves multiple lipid parameters but is underused owing to niacin-induced flushing (NIF). Laropiprant (LRPT) reduces NIF; however, its effects on chronic flushing (6 months) have not been studied. We examined whether a
Autor:
Debra Kush, Da Yi Hu, Christine McCrary Sisk, Waheeda Sirah, Hyo-Soo Kim, Ji Liu, John F. Paolini, Aditi Sapre, Darbie Maccubbin
Publikováno v:
Journal of Clinical Lipidology. 3:179-186
Niacin has proven lipid-modifying efficacy and cardiovascular benefit; however, it is underused because of skin flushing, a process mediated primarily by prostaglandin D(2) (PGD(2)). Laropiprant (LRPT), a PGD(2) receptor (DP1) antagonist that mitigat
Autor:
Hyo-Soo Kim, Da-Yi Hu, Christine McCrary Sisk, Darbie Maccubbin, Waheeda Sirah, John F. Paolini, Erluo Chen, Debra Kush, Ping Ye
Publikováno v:
Cardiology. 114:192-198
Objective: Niacin is underutilized due to flushing, which occurs in over 90% of niacin-treated patients. Laropiprant (LRPT) reduces flushing associated with niacin. This study compared flushing with a combination tablet of extended-release (ER) niaci
Autor:
John F. Paolini, Abigaile Betteridge, Anders G. Olsson, Robert Reyes, A. Elis, C. McCrary Sisk, Qinfen Yu, Harold E. Bays, Waheeda Sirah, Olga M. Kuznetsova, Richard C. Pasternak, Darbie Maccubbin, V. Elinoff, Yale B. Mitchel
Publikováno v:
International Journal of Clinical Practice. 62:1959-1970
Summary Background: Improving lipids beyond low-density lipoprotein cholesterol (LDL-C) lowering with statin monotherapy may further reduce cardiovascular risk. Niacin has complementary lipid-modifying efficacy to statins and cardiovascular benefit,
Autor:
Geraldine Macdonell, Dieter Lütjohann, Thomas Musliner, Waheeda Sirah, J. Lin, Amish P. Shah, Amy O. Johnson-Levonas, Aditi Sapre, K. von Bergmann
Publikováno v:
International Journal of Clinical Practice. 62:1499-1510
Summary Objective: To assess the long-term efficacy and safety profile of ezetimibe 10 mg/day in patients with homozygous sitosterolemia. Methods: This was an extension of a multi-centre, randomised, double-blind, placebo-controlled base study in whi
Autor:
Gerald Salen, Waheeda Sirah, C. McCrary Sisk, K. von Bergmann, Thomas Musliner, Dieter Lütjohann, Aditi Sapre, D. Cselovszky
Publikováno v:
International Journal of Clinical Practice. 62:995-1000
Summary Objective: To assess the effect of ezetimibe (EZE) 40 mg/day on non-cholesterol sterol plasma concentrations in patients with homozygous sitosterolaemia (HoS). Methods: This was a multi-centre, randomised, double-blind, placebo-controlled par
Autor:
Luzelena Caro, Cynthia Cuffie, Yale B. Mitchel, Dominic P. Behan, Richard L. Dunbar, Laurence B. Peterson, Jiajun Liu, John F. Paolini, Daniel T. Connolly, Steven L. Colletti, Tsuei-Ju Wu, Graeme Semple, P. Douglas Boatman, Josee Cote, Kenneth K. Wu, Waheeda Sirah, Jayne Chin, Samuel D. Wright, Andrew K.P. Taggart, John A. Wagner, Daniel J. Rader, Brett Lauring, James R. Tata, Kang Cheng, Andrew S. Plump, M. Gerard Waters, Lan Jin, Alexandra MacLean, Sauzanne Khalilieh, Adam B. Polis, Wen-Lin Luo, Eseng Lai, Xuan Liu
Publikováno v:
Science translational medicine. 4(148)
Nicotinic acid (niacin) induces beneficial changes in serum lipoproteins and has been associated with beneficial cardiovascular effects. Niacin reduces low-density lipoprotein, increases high-density lipoprotein, and decreases triglycerides. It is we
Autor:
Erluo Chen, Peder Blomqvist, Fabian Chen, Waheeda Sirah, Lizhen Yan, Michael H. Davidson, Christine McCrary Sisk, James M. McKenney, Darbie Maccubbin
Publikováno v:
International journal of cardiology. 167(1)
Extended-release niacin/laropiprant (ERN/LRPT) reduces flushing and preserves the lipid-modifying effects of ERN. This study compared the efficacy and safety of ERN/LRPT plus simvastatin (ERN/LRPT+SIMVA) with atorvastatin (ATORVA) in patients with mi
Autor:
John K. Troxell, Claude Gagné, Pedro Mata, Waheeda Sirah, Luis Masana, Alan G. Meehan, Barry Gumbiner, Amy O. Johnson-Levonas, Meehyung Cho
Publikováno v:
Clinical therapeutics. 27(2)
Background: Ezetimibe (EZE) is a cholesterol-loweringdrug that inhibits absorption of dietary and biliary cholesterol across the intestinal wall without affecting absorption of bile acids, fatty acids, fat-soluble vitamins, or triglycerides. It has a
Autor:
Thomas Musliner, K. von Bergmann, Waheeda Sirah, D. Luetjohann, J. Lin, Amish P. Shah, Aditi Sapre, Amy O. Johnson-Levonas
Publikováno v:
Atherosclerosis Supplements. 9:189