Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Wahed Zedan"'
Autor:
Hampus Hedlund, Hampus Du Rietz, Johanna M. Johansson, Hanna C. Eriksson, Wahed Zedan, Linfeng Huang, Jonas Wallin, Anders Wittrup
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Endosomal escape and subsequent cytosolic delivery of siRNA therapeutics is inefficient, and quantification is difficult. Here the authors report a confocal microscopy-based method to quantify cytosolic delivery of fluorescently labelled siRNA during
Externí odkaz:
https://doaj.org/article/47df8d79ce954f14a790a888afd14d96
Autor:
David Ulmert, Daniel Thorek, Hans Lilja, Steven M. Larson, Robert Damoiseaux, Robert J. Klein, Norbert Peekhaus, Wahed Zedan, Diane Abou, Ken Herrmann, Julie E. Park, Teja Kalidindi, Michael R. McDevitt, Gabriel Adrian, Katharina Lückerath, Darren R. Veach, Mesude Bicak, Mohamed Altai, Claire M. Storey
S1. Hierarchical clustering based on Euclidean distance of RNA-seq data demonstrates separation of EBRT-treated (B1-3) and untreated (C1-3) samples.S2. Multi-dimensional scaling plot of RNA-seq data demonstrates separation of EBRT-treated (B1-3) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1377f5f545ae64255126d352d870e4e0
https://doi.org/10.1158/1541-7786.22551840
https://doi.org/10.1158/1541-7786.22551840
Autor:
David Ulmert, Daniel Thorek, Hans Lilja, Steven M. Larson, Robert Damoiseaux, Robert J. Klein, Norbert Peekhaus, Wahed Zedan, Diane Abou, Ken Herrmann, Julie E. Park, Teja Kalidindi, Michael R. McDevitt, Gabriel Adrian, Katharina Lückerath, Darren R. Veach, Mesude Bicak, Mohamed Altai, Claire M. Storey
Noninvasive biomarkers for androgen receptor (AR) pathway activation are urgently needed to better monitor patient response to prostate cancer therapies. AR is a critical driver and mediator of resistance of prostate cancer but currently available no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0445efa2285bf786789e370019ca125b
https://doi.org/10.1158/1541-7786.c.6534810
https://doi.org/10.1158/1541-7786.c.6534810
Autor:
Amanda Kristiansson, Anders Örbom, Jonas Ahlstedt, Helena Karlsson, Wahed Zedan, Magnus Gram, Bo Åkerström, Sven-Erik Strand, Mohamed Altai, Joanna Strand, Oskar Vilhelmsson Timmermand
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 263 (2021)
Anti-prostate specific membrane antigen (PSMA) radioligand therapy is promising but not curative in castration resistant prostate cancer. One way to broaden the therapeutic index could be to administer higher doses in combination with radioprotectors
Externí odkaz:
https://doaj.org/article/0ced114b239f4017a82234fa24ba0191
Autor:
Claire M. Storey, Mohamed Altai, Mesude Bicak, Darren R. Veach, Katharina Lückerath, Gabriel Adrian, Michael R. McDevitt, Teja Kalidindi, Julie E. Park, Ken Herrmann, Diane Abou, Wahed Zedan, Norbert Peekhaus, Robert J. Klein, Robert Damoiseaux, Steven M. Larson, Hans Lilja, Daniel Thorek, David Ulmert
Noninvasive biomarkers for androgen receptor (AR) pathway activation are urgently needed to better monitor patient response to prostate cancer therapies. AR is a critical driver and mediator of resistance of prostate cancer but currently available no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6220d4c184d7986fdc440382cf0a767f
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85151575199
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85151575199
Autor:
Claire M Storey, Mohamed Altai, Mesude Bicak, Darren R Veach, Katharina Lückerath, Gabriel Adrian, Michael R McDevitt, Teja Kalidindi, Julie E Park, Ken Herrmann, Diane Abou, Wahed Zedan, Norbert Peekhaus, Robert J Klein, Robert Damoiseaux, Steven M Larson, Hans Lilja, Daniel Thorek, David Ulmert
External beam radiotherapy (EBRT) remains a common treatment for all stages of PCa, but DNA damage induced by EBRT upregulates androgen receptor (AR) pathway activity to promote therapeutic resistance. [89Zr]11B6-PET is a novel modality targeting pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b44b4f410b2a34affb530841fa9dac6f
https://doi.org/10.1101/2022.06.23.497290
https://doi.org/10.1101/2022.06.23.497290
Autor:
Strand, Oskar Vilhelmsson Timmermand, Anders Örbom, Mohamed Altai, Wahed Zedan, Bo Holmqvist, Marcella Safi, Thuy A. Tran, Sven-Erik Strand, Joanna
Publikováno v:
Cancers; Volume 13; Issue 14; Pages: 3469
Background: The humanized monoclonal antibody (mAb) hu5A10 specifically targets and internalizes prostate cancer cells by binding to prostate specific antigen (PSA). Preclinical evaluations have shown that hu5A10 is an excellent vehicle for prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::7d86c3288243079c470539b88908a07e
Autor:
Oskar Vilhelmsson Timmermand, Anders Örbom, Mohamed Altai, Wahed Zedan, Bo Holmqvist, Marcella Safi, Thuy A. Tran, Sven-Erik Strand, Joanna Strand
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3469, p 3469 (2021)
Cancers, Vol 13, Iss 3469, p 3469 (2021)
Simple Summary The present study demonstrates that a radiolabeling strategy can positively modify hu5A10′s capacity to bind PSA and complex with the FcRn receptor, which results in a more homogenous activity distribution in tumors and enhanced ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a8e7285c640111247db4f8edb7ddeacb
https://pubmed.ncbi.nlm.nih.gov/34298682
https://pubmed.ncbi.nlm.nih.gov/34298682
Autor:
Ortenlöf, Niklas1 (AUTHOR), Vallius, Suvi1 (AUTHOR), Karlsson, Helena2 (AUTHOR), Ekström, Claes2 (AUTHOR), Kristiansson, Amanda2 (AUTHOR), Holmqvist, Bo3 (AUTHOR), Göransson, Olga4 (AUTHOR), Vaváková, Magdaléna4 (AUTHOR), Rydén, Martin5 (AUTHOR), Carey, Galen6 (AUTHOR), Barton, Norman7 (AUTHOR), Ley, David2 (AUTHOR), Gram, Magnus2 (AUTHOR) magnus.gram@med.lu.se
Publikováno v:
Fluids & Barriers of the CNS. 8/15/2023, Vol. 20 Issue 1, p1-18. 18p.
Autor:
Mellhammar, Emma1 (AUTHOR) emma.mellhammar@med.lu.se, Dahlbom, Magnus2 (AUTHOR), Vilhelmsson-Timmermand, Oskar1,3 (AUTHOR), Strand, Sven-Erik4 (AUTHOR)
Publikováno v:
EJNMMI Physics. 7/19/2022, Vol. 9 Issue 1, p1-20. 20p.