Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Wahajul Haq"'
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101282- (2024)
Synthesis and characterization of drug metabolites has emerged as an important area of research in consideration to the significant contribution of studies on metabolites in drug research. The present work comprises synthesis of 2-(4-((4-chlorophenyl
Externí odkaz:
https://doaj.org/article/bdf26fa0e5f045cb8576b58d4dedc981
Autor:
Vinay Shankar Tiwari, Prince Joshi, Kanchan Yadav, Anamika Sharma, Sushobhan Chowdhury, Ashan Manhas, Niti Kumar, Renu Tripathi, Wahajul Haq
Publikováno v:
ACS Omega, Vol 6, Iss 20, Pp 12984-12994 (2021)
Externí odkaz:
https://doaj.org/article/4b06e4d5f42645c7acffd8bec9ae993a
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100417- (2022)
A facile method for the reduction of carboxylic acid group of Bezafibrate, an approved drug, is described. The selective reduction of carboxylic acid group to corresponding alcohol was carried out by activation of the carboxylic acid moiety via mixed
Externí odkaz:
https://doaj.org/article/18e941f5e53d4bb3b396991db754e06a
Autor:
Mehraj-U-Din Lone, Javed Miyan, Mohammad Asif, Showkat A. Malik, Parul Dubey, Varsha Singh, Kavita Singh, Kalyan Mitra, Deepali Pandey, Wahajul Haq, Himanshi Amita, Prince Kumar Singh, Wieland Kiess, Franziska Kaessner, Antje Garten, Smrati Bhadauria
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-16 (2019)
Abstract Background The mechanistic (or mammalian) target of rapamycin (mTOR), a Ser/Thr kinase, associates with different subunits forming two functionally distinct complexes, mTORC1 and mTORC2, regulating a diverse set of cellular functions in resp
Externí odkaz:
https://doaj.org/article/56602a031c1b438ea006f2e7d0d70b22
Publikováno v:
Results in Chemistry, Vol 2, Iss , Pp 100018- (2020)
Synthetic routes for the preparation of (i) isopropyl 2-(4-(4-chlorobenzyl)phenoxy)-2-methyl propanoate (Reduced Fenofibrate, Fibrane) (2) from isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate (Fenofibrate) (1) in a single step is establis
Externí odkaz:
https://doaj.org/article/7d4597b71d7e48a8bfb5217e13c5484c
Autor:
Sumit Joshi, Narendra Kumar Yadav, Keerti Rawat, Vikash Kumar, Rafat Ali, Amogh Anant Sahasrabuddhe, Mohammad Imran Siddiqi, Wahajul Haq, Shyam Sundar, Anuradha Dube
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Development of a suitable vaccine against visceral leishmaniasis (VL), a fatal parasitic disease, is considered to be vital for maintaining the success of kala-azar control programs. The fact that Leishmania-infected individuals generate life-long im
Externí odkaz:
https://doaj.org/article/0a84d6e233e246568e0bb78eb3206f42
Autor:
Rahul Shivahare, Preeti Vishwakarma, Naveen Parmar, Pawan Kumar Yadav, Wahajul Haq, Mrigank Srivastava, Suman Gupta, Susanta Kar
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94596 (2014)
Immuno-modulators in combination with antileishmanial drug miltefosine is a better therapeutic approach for treatment of Visceral Leishmaniasis (VL) as it not only reduces the dose of miltefosine but also shortens the treatment regimen. However, immu
Externí odkaz:
https://doaj.org/article/688ecedf1c5d4390a8f65de6fc86ec70
Autor:
Dharamsheela Thakur, Reshu Saxena, Vandana Singh, Wahajul Haq, S B Katti, Bhupendra Narain Singh, Raj Kamal Tripathi
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45905 (2012)
Immunostimulatory peptides potentiate the immune system of the host and are being used as a viable adjunct to established therapeutic modalities in treatment of cancer and microbial infections. Several peptides derived from milk protein have been rep
Externí odkaz:
https://doaj.org/article/83b0e0ca7ad6455faadcc7318b191b4a
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 4, Iss 1, p 14 (2008)
In search of new erythromycin derivatives 3-O-[γ-(4-oxo-2-aryl-thiazolidin-3-yl)butyryl]erythromycin A derivatives have been synthesized. The 3-hydroxy group was derivatised to a primary amine and subsequently the thiazolidinone nucleus was generate
Externí odkaz:
https://doaj.org/article/4ff7346eab0247919deb0dd0eb1447af
Publikováno v:
International Journal of Organic Chemistry. 12:116-125
A highly efficient and facile protocol for the selective reduction of carboxylic acid of Fenofibric acid to corresponding alcohol was developed. The selective reduction was carried out by activation of carboxylic acid by mixed anhydride followed by t