Výsledky vyhledávání - "Wahafu Alafate"

Akademický článek

Targeting ARNT attenuates chemoresistance through destabilizing p38α-MAPK signaling in glioblastoma

Autor: Wahafu Alafate, Gen Lv, Jiantao Zheng, Haiping Cai, Wei Wu, Yong Yang, Shichao Du, Dong Zhou, Peng Wang

Publikováno v: Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)

Abstract Glioblastoma (GBM) is the most aggressive and lethal brain tumor in adults. This study aimed to investigate the functional significance of aryl hydrocarbon receptor nuclear translocator (ARNT) in the pathogenesis of GBM. Analysis of public d

Externí odkaz: https://doaj.org/article/24bec38b1b214a64abafb815d4d66cb6

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Akademický článek

NEK2 enhances malignancies of glioblastoma via NIK/NF-κB pathway

Autor: Jianyang Xiang, Wahafu Alafate, Wei Wu, Yichang Wang, Xiaodong Li, Wanfu Xie, Xiaobin Bai, Ruichun Li, Maode Wang, Jia Wang

Publikováno v: Cell Death and Disease, Vol 13, Iss 1, Pp 1-13 (2022)

Abstract Glioblastoma (GBM) is one of the most lethal primary brain tumor with a poor median survival less than 15 months. Despite the development of the clinical strategies over the decades, the outcomes for GBM patients remain dismal due to the str

Externí odkaz: https://doaj.org/article/7f9897682f2b4a66b5ee74e0fa77677a

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Akademický článek

Loss of PLK2 induces acquired resistance to temozolomide in GBM via activation of notch signaling

Autor: Wahafu Alafate, Dongze Xu, Wei Wu, Jianyang Xiang, Xudong Ma, Wanfu Xie, Xiaobin Bai, Maode Wang, Jia Wang

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-14 (2020)

Abstract Background Glioblastoma (GBM) is a lethal type of primary brain tumor with a median survival less than 15 months. Despite the recent improvements of comprehensive strategies, the outcomes for GBM patients remain dismal. Accumulating evidence

Externí odkaz: https://doaj.org/article/280d627c787c45008a0f40ee3f8d44a3

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Akademický článek

Preoperative Prediction Nomogram Based on Integrated Profiling for Glioblastoma Multiforme in Glioma Patients

Autor: Wei Wu, Zhong Deng, Wahafu Alafate, Yichang Wang, Jianyang Xiang, Lizhe Zhu, Bolin Li, Maode Wang, Jia Wang

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Introduction: Traditional classification that divided gliomas into glioblastoma multiformes (GBM) and lower grade gliomas (LGG) based on pathological morphology has been challenged over the past decade by improvements in molecular stratification, how

Externí odkaz: https://doaj.org/article/d8fe212d479b4e179273fabf83700dbf

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