Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Wah Chin, Boon"'
Autor:
Christos Symeonides, Kristina Vacy, Sarah Thomson, Sam Tanner, Hui Kheng Chua, Shilpi Dixit, Toby Mansell, Martin O’Hely, Boris Novakovic, Julie B. Herbstman, Shuang Wang, Jia Guo, Jessalynn Chia, Nhi Thao Tran, Sang Eun Hwang, Kara Britt, Feng Chen, Tae Hwan Kim, Christopher A. Reid, Anthony El-Bitar, Gabriel B. Bernasochi, Lea M. Durham Delbridge, Vincent R. Harley, Yann W. Yap, Deborah Dewey, Chloe J. Love, David Burgner, Mimi L. K. Tang, Peter D. Sly, Richard Saffery, Jochen F. Mueller, Nicole Rinehart, Bruce Tonge, Peter Vuillermin, the BIS Investigator Group, Anne-Louise Ponsonby, Wah Chin Boon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Male sex, early life chemical exposure and the brain aromatase enzyme have been implicated in autism spectrum disorder (ASD). In the Barwon Infant Study birth cohort (n = 1074), higher prenatal maternal bisphenol A (BPA) levels are associate
Externí odkaz:
https://doaj.org/article/61103e53974f40858070213fe5e84473
Autor:
Kristina Vacy, Sarah Thomson, Archer Moore, Alex Eisner, Sam Tanner, Cindy Pham, Richard Saffrey, Toby Mansell, David Burgner, Fiona Collier, Peter Vuillermin, Martin O’Hely, Wah Chin Boon, Peter Meikle, Satvika Burugupalli, Anne-Louise Ponsonby, Mimi L.K. Tang, Lawrence Gray, Sarath Ranganathan, Peter Sly, Jochen Mueller, Terry Dwyerm, John Carlin
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104949- (2024)
Summary: Background: Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are neurodevelopmental conditions with early life origins. Alterations in blood lipids have been linked to ADHD and ASD; however, prospective earl
Externí odkaz:
https://doaj.org/article/c5338cc2a86d4472b1c7a40b6069e7a3
Autor:
Victoria M. McLeod, Mathew D. F. Chiam, Nirma D. Perera, Chew L. Lau, Wah Chin Boon, Bradley J. Turner
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Sex steroid hormones have been implicated as disease modifiers in the neurodegenerative disorder amyotrophic lateral sclerosis (ALS). Androgens, signalling via the androgen receptor (AR), predominate in males, and have widespread actions in the perip
Externí odkaz:
https://doaj.org/article/92fd79cd0a5a4fa5aab2084315b116af
Autor:
Genevieve V. Dall, Jessica L. Vieusseux, Kenneth S. Korach, Yukitomo Arao, Sylvia C. Hewitt, Katherine J. Hamilton, Elaine Dzierzak, Wah Chin Boon, Evan R. Simpson, Robert G. Ramsay, Torsten Stein, Joanne S. Morris, Robin L. Anderson, Gail P. Risbridger, Kara L. Britt
Publikováno v:
Stem Cell Reports, Vol 8, Iss 2, Pp 417-431 (2017)
Estrogen stimulates breast development during puberty and mammary tumors in adulthood through estrogen receptor-α (ERα). These effects are proposed to occur via ERα+ luminal cells and not the mammary stem cells (MaSCs) that are ERαneg. Since ERα
Externí odkaz:
https://doaj.org/article/451b048dd31a4d51af09091027b98444
Autor:
Victoria M, McLeod, Mathew D F, Chiam, Nirma D, Perera, Chew L, Lau, Wah Chin, Boon, Bradley J, Turner
Publikováno v:
Frontiers in endocrinology. 13
Sex steroid hormones have been implicated as disease modifiers in the neurodegenerative disorder amyotrophic lateral sclerosis (ALS). Androgens, signalling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a11915f2cbb22d865f702cc03052736
https://pubmed.ncbi.nlm.nih.gov/35273564
https://pubmed.ncbi.nlm.nih.gov/35273564
Autor:
Michelle L Van Sinderen, Gregory R Steinberg, Sebastian B Jørgensen, Jane Honeyman, Jenny D Chow, Kerrie A Herridge, Amy L Winship, Evdokia Dimitriadis, Margaret E E Jones, Evan R Simpson, Wah Chin Boon
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136143 (2015)
The maintenance of glucose homeostasis within the body is crucial for constant and precise performance of energy balance and is sustained by a number of peripheral organs. Estrogens are known to play a role in the maintenance of glucose homeostasis.
Externí odkaz:
https://doaj.org/article/553c991278d747b2b5f9f923ad908507
Autor:
Davor Stanić, Sydney Dubois, Hui Kheng Chua, Bruce Tonge, Nicole Rinehart, Malcolm K Horne, Wah Chin Boon
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90451 (2014)
Aromatase catalyses the last step of oestrogen synthesis. There is growing evidence that local oestrogens influence many brain regions to modulate brain development and behaviour. We examined, by immunohistochemistry, the expression of aromatase in t
Externí odkaz:
https://doaj.org/article/b2e38d824c5a47d18d7429725ba8da1c
Autor:
Michelle L Van Sinderen, Gregory R Steinberg, Sebastian B Jørgensen, Sarah Q To, Kevin C Knower, Colin D Clyne, Jane Honeyman, Jenny D Chow, Kerrie A Herridge, Margaret E E Jones, Evan R Simpson, Wah Chin Boon
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87230 (2014)
Estrogens are known to play a role in modulating metabolic processes within the body. The Aromatase knockout (ArKO) mice have been shown to harbor factors of Metabolic syndrome with central adiposity, hyperinsulinemia and male-specific hepatic steato
Externí odkaz:
https://doaj.org/article/23c50909e3f348f3a1f35cec7dfbaf44
Publikováno v:
Organic Communications. Jul-Sep2018, Vol. 11 Issue 3, p168-172. 5p.
Autor:
Doris Tomas, Victoria M. McLeod, Mathew D. F. Chiam, Nayomi Wanniarachchillage, Wah Chin Boon, Bradley J. Turner
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder caused by loss of motor neurons. ALS incidence is skewed towards males with typically earlier age of onset and limb site of onset. The androgen receptor (AR) is the majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a01b88145bbb0e5e08a3e5e823414ea
https://pubmed.ncbi.nlm.nih.gov/33927243
https://pubmed.ncbi.nlm.nih.gov/33927243