Single cell variant to enhancer to gene map for coronary artery disease.

Autor: Amrute JM; Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA.; Amgen Research, South San Francisco, CA, 94080, USA., Lee PC; Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA., Eres I; Amgen Research, South San Francisco, CA, 94080, USA., Lee CJM; Cardiovascular Metabolic Disease Translational Research Programme, National University Health System, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore.; Institute of Molecular and Cell Biology, 61 Biopolis Drive, Singapore 138673, Singapore., Bredemeyer A; Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA., Sheth MU; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA., Yamawaki T; Amgen Research, South San Francisco, CA, 94080, USA., Gurung R; Cardiovascular Metabolic Disease Translational Research Programme, National University Health System, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore.; Institute of Molecular and Cell Biology, 61 Biopolis Drive, Singapore 138673, Singapore., Anene-Nzelu C; Montreal Heart Institute, Montreal, 5000 Rue Belanger, QC, H1T 1C8, Canada.; Department of Medicine, Université de Montréal, 2900 Edouard Montpetit Blvd, Montréal, QC, H3T 1J4, Canada., Qiu WL; Department of Biology, University of Copenhagen, Copenhagen, Denmark.; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute, Cambridge, MA, USA., Kundu S; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Li DY; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305., Ramste M; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305., Lu D; Amgen Research, South San Francisco, CA, 94080, USA., Tan A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA., Kang CJ; Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA., Wagoner RE; Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA., Alisio A; Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA., Cheng P; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305., Zhao Q; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305., Miller CL; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville., Hall IM; Center for Genomic Health, Yale University, New Haven, CT, 06510, USA.; Department of Genetics, Yale University, New Haven, CT, 06510, USA., Gupta RM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Divisions of Genetics and Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hsu YH; Amgen Research, South San Francisco, CA, 94080, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA., Haldar SM; Amgen Research, South San Francisco, CA, 94080, USA., Lavine KJ; Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA.; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, 63110, USA.; Department of Developmental Biology, Washington University School of Medicine, Saint Louis, MO, 63110, USA., Jackson S; Amgen Research, South San Francisco, CA, 94080, USA., Andersson R; Department of Biology, University of Copenhagen, Copenhagen, Denmark.; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute, Cambridge, MA, USA., Engreitz JM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA.; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute, Cambridge, MA, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA., Foo RS; Cardiovascular Metabolic Disease Translational Research Programme, National University Health System, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore.; Institute of Molecular and Cell Biology, 61 Biopolis Drive, Singapore 138673, Singapore., Li CM; Amgen Research, South San Francisco, CA, 94080, USA., Ason B; Amgen Research, South San Francisco, CA, 94080, USA., Quertermous T; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305., Stitziel NO; Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, 63110, USA.; Department of Genetics, Washington University School of Medicine, Saint Louis, MO, 63110, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Nov 13. Date of Electronic Publication: 2024 Nov 13.