Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wagner S. da-Silva"'
Autor:
Evandro A. De-Souza, Felipe S. A. Pimentel, Caio M. Machado, Larissa S. Martins, Wagner S. da-Silva, Mónica Montero-Lomelí, Claudio A. Masuda
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 1, Pp 55-61 (2014)
Classic galactosemia is a human autosomal recessive disorder caused by mutations in the GALT gene (GAL7 in yeast), which encodes the enzyme galactose-1-phosphate uridyltransferase. Here we show that the unfolded protein response pathway is triggered
Externí odkaz:
https://doaj.org/article/0d328464420d429e8395af3ccb6fae5a
Autor:
Sarah Crunkhorn, Wagner S. Da Silva, Ryan Faucette, Farrell Dearie, Antonio C. Bianco, Mary-Elizabeth Patti, Daniel Espinoza, Kristen Barry, Christos S. Mantzoros, Hiral Gami
Publikováno v:
Journal of Biological Chemistry. 282:15439-15450
Peroxisome proliferator activator receptor-γ coactivator 1 (PGC-1) is a major candidate gene for diabetes-related metabolic phenotypes, contributing to decreased expression of nuclear-encoded mitochondrial genes in muscle and adipose tissue. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c99787861f42bc49a2e03d34e4293d82
https://doi.org/10.1074/jbc.m611214200
https://doi.org/10.1074/jbc.m611214200
Autor:
Wagner S. Da Silva, Stephen A. Huang, Praful S. Singru, Ronald M. Lechan, Antonio C. Bianco, David F. Gordon, John W. Harney, Rogerio S. Ribeiro, E. Chester Ridgway, Marcelo A. Christoffolete, P. Reed Larsen, Csaba Fekete, Alessandra Crescenzi
Publikováno v:
Endocrinology. 147:1735-1743
T(4), the main product of thyroid secretion, is a critical signal in plasma that mediates the TSH-negative feedback mechanism. As a prohormone, T(4) must be converted to T(3) to acquire biological activity; thus, type 2 iodothyronine deiodinase (D2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c914352b753467ee8f5dba0b42e42ba1
https://doi.org/10.1210/en.2005-1300
https://doi.org/10.1210/en.2005-1300
Autor:
Jason K. Kim, Stephen P. Seslar, Eun Gyoung Hong, Ki Won Lee, Timothy W. Yu, Charles I. Berul, Wagner S. Da Silva, Hiroko Wakimoto, Dae Young Jung, Antonio C. Bianco, Jong Hun Kim, Randall H. Friedline, Kerry S. Russell, P. Reed Larsen, Brian W. Kim, Suzy D.C. Bianco
Publikováno v:
Endocrinology. 154(10)
Altered glucose metabolism in the heart is an important characteristic of cardiovascular and metabolic disease. Because thyroid hormones have major effects on peripheral metabolism, we examined the metabolic effects of heart-selective increase in T3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e66f2b266714cc14fa628d910ac164b
https://pubmed.ncbi.nlm.nih.gov/23861374
https://pubmed.ncbi.nlm.nih.gov/23861374
Autor:
Antonio C. Bianco, Anikó Zeöld, Judit Menyhért, Balázs Gereben, Michael C. Haffner, Márton Doleschall, Csaba Fekete, Zsolt Liposits, Wagner S. Da Silva, Imre Kacskovics, Luciane P. Capelo
Publikováno v:
Endocrinology. 147(9)
Type 2 iodothyronine deiodinase (D2) activates T4 by deiodination to T3, a process being the source of most T3 present in the brain. In the mediobasal hypothalamus, expression of the dio2 gene is potently activated by administration of bacterial lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e6bc9212de63a1d6127220dd1a0f08
https://pubmed.ncbi.nlm.nih.gov/16728495
https://pubmed.ncbi.nlm.nih.gov/16728495
Publikováno v:
The Journal of biological chemistry. 279(44)
With yeast-soluble inorganic pyrophosphatase, the heat released during PP(i) hydrolysis was -6.3 kcal/mol regardless of the KCl concentration in the medium. With the membrane-bound pyrophosphatase of corn vacuoles, the heat released varies between -2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbb29332db3811214b62c274bb6095d4
https://pubmed.ncbi.nlm.nih.gov/15322117
https://pubmed.ncbi.nlm.nih.gov/15322117
Autor:
Leonardo M Saraiva, Gisele S Seixas da Silva, Antonio Galina, Wagner S da-Silva, William L Klein, Sérgio T Ferreira, Fernanda G De Felice
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15230 (2010)
Brain accumulation of the amyloid-β peptide (Aβ) and oxidative stress underlie neuronal dysfunction and memory loss in Alzheimer's disease (AD). Hexokinase (HK), a key glycolytic enzyme, plays important pro-survival roles, reducing mitochondrial re
Externí odkaz:
https://doaj.org/article/1fefc9085b5a472a94a10a22fe63bf4b