Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp

Autor: Wagner, Jérôme E, Monsarrat, Clément, Compain, Guillaume, André, Christophe, Engilberge, Sylvain, Martiel, Isabelle, Oliéric, Vincent, Wolff, Philippe, Brillet, Karl, Landolfo, Marie, Silva da Veiga, Cyrielle, WAGNER, Jérôme, Guichard, Gilles, Burnouf, Dominique

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (23), pp.17063-17078. ⟨10.1021/acs.jmedchem.1c00918⟩

The bacterial DNA sliding clamp (SC), or replication processivity factor, is a promising target for the development of novel antibiotics. We report a structure-activity relationship study of a new series of peptides interacting within the Escherichia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bb7e683da14746f2278e73da19b114
https://doi.org/10.1021/acs.jmedchem.1c00918

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Numerical analysis of stress tensor mapping without an external solver.

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Publikováno v: PAMM: Proceedings in Applied Mathematics & Mechanics; Mar2023, Vol. 22 Issue 1, p1-6, 6p

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