A Computationally Guided Approach to Improve Expression of VHH Binders.

Autor: Ozdemir, Emine Sila, Tolley, Jessica, Goncalves, Florian, Gomes, Michelle, Wagnell, Eli, Branchaud, Bruce, Dubrovskaya, Viktoriya, Ranganathan, Srivathsan V.

Publikováno v: Biophysica; Dec2024, Vol. 4 Issue 4, p573-585, 13p

Turning antibodies off and on again using a covalently tethered blocking peptide.

Autor: Brasino, Michael¹ (AUTHOR) brasino@ohsu.edu, Wagnell, Eli¹ (AUTHOR), Hamilton, Sean^1,2 (AUTHOR), Ranganathan, Srivathsan¹ (AUTHOR), Gomes, Michelle M.¹ (AUTHOR), Branchaud, Bruce¹ (AUTHOR), Messmer, Bradley³ (AUTHOR), Ibsen, Stuart D.^1,2 (AUTHOR) Ibsen@ohsu.edu

Publikováno v: Communications Biology. 12/10/2022, Vol. 5 Issue 1, p1-9. 9p.

Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in Lactiplantibacillus plantarum WCFS1.

Autor: Brasino M; Cancer Early Detection Advanced Research (CEDAR) Center, Knight Cancer Institute, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA., Wagnell E; Cancer Early Detection Advanced Research (CEDAR) Center, Knight Cancer Institute, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA., Ozdemir ES; Cancer Early Detection Advanced Research (CEDAR) Center, Knight Cancer Institute, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA., Ranganathan S; Cancer Early Detection Advanced Research (CEDAR) Center, Knight Cancer Institute, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA., Merritt J; Department of Biomaterial and Biomedical Sciences, School of Dentistry, Oregon Health and Science University, Portland, Oregon, USA.; Department of Molecular Microbiology and Immunology, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA.

Publikováno v: Microbiology spectrum [Microbiol Spectr] 2024 Jun 04; Vol. 12 (6), pp. e0051724. Date of Electronic Publication: 2024 Apr 30.