Adult Lysophosphatidic Acid Receptor 1-Deficient Rats with Hyperoxia-Induced Neonatal Chronic Lung Disease Are Protected against Lipopolysaccharide-Induced Acute Lung Injury.

Autor: Chen X; Laboratory of Neonatology, Division of Neonatology, Department of Pediatrics, Leiden University Medical Center Leiden, Netherlands., Walther FJ; Laboratory of Neonatology, Division of Neonatology, Department of Pediatrics, Leiden University Medical CenterLeiden, Netherlands; Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical CenterTorrance, CA, USA., Laghmani EH; Laboratory of Neonatology, Division of Neonatology, Department of Pediatrics, Leiden University Medical Center Leiden, Netherlands., Hoogeboom AM; Laboratory of Neonatology, Division of Neonatology, Department of Pediatrics, Leiden University Medical Center Leiden, Netherlands., Hogen-Esch AC; Laboratory of Neonatology, Division of Neonatology, Department of Pediatrics, Leiden University Medical Center Leiden, Netherlands., van Ark I; Department of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University Utrecht, Netherlands., Folkerts G; Department of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University Utrecht, Netherlands., Wagenaar GT; Laboratory of Neonatology, Division of Neonatology, Department of Pediatrics, Leiden University Medical Center Leiden, Netherlands.

Publikováno v: Frontiers in physiology [Front Physiol] 2017 Mar 22; Vol. 8, pp. 155. Date of Electronic Publication: 2017 Mar 22 (Print Publication: 2017).

Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice.

Autor: Heestermans M; Einthoven Laboratory for Experimental Vascular Medicine, Department of Internal Medicine, Division of Thrombosis and Hemostasis., Salloum-Asfar S; Einthoven Laboratory for Experimental Vascular Medicine, Department of Internal Medicine, Division of Thrombosis and Hemostasis., Salvatori D; Central Laboratory Animal Facility, and., Laghmani el H; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands;, Luken BM; Department of Immunopathology, Sanquin-Academic Medical Center Landsteiner Laboratory, Amsterdam, The Netherlands;, Zeerleder SS; Department of Immunopathology, Sanquin-Academic Medical Center Landsteiner Laboratory, Amsterdam, The Netherlands;, Spronk HM; Department of Internal Medicine and Biochemistry, Maastricht University, Maastricht, The Netherlands; and., Korporaal SJ; Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands., Wagenaar GT; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands;, Reitsma PH; Einthoven Laboratory for Experimental Vascular Medicine, Department of Internal Medicine, Division of Thrombosis and Hemostasis., van Vlijmen BJ; Einthoven Laboratory for Experimental Vascular Medicine, Department of Internal Medicine, Division of Thrombosis and Hemostasis.

Publikováno v: Blood [Blood] 2016 May 26; Vol. 127 (21), pp. 2630-7. Date of Electronic Publication: 2016 Mar 01.

Therapeutic potential of soluble guanylate cyclase modulators in neonatal chronic lung disease.

Autor: Wagenaar GT; Laboratory of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, the Netherlands; g.t.m.wagenaar@lumc.nl., Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, Leiden, the Netherlands; and., Gosens R; Department of Molecular Pharmacology and Groningen Research Institute for Asthma and Chronic Obstructive Pulmonary Disease, University of Groningen, Groningen, The Netherlands.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2015 Nov 15; Vol. 309 (10), pp. L1037-40. Date of Electronic Publication: 2015 Oct 02.

Spatial and temporal expression of immunoglobulin superfamily member 1 in the rat.

Autor: Joustra SD; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands s.d.joustra@lumc.nl., Meijer OC; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Heinen CA; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Mol IM; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Laghmani el H; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Sengers RM; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Carreno G; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., van Trotsenburg AS; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Biermasz NR; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Bernard DJ; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Wit JM; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Oostdijk W; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., van Pelt AM; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Hamer G; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands., Wagenaar GT; Department of PediatricsLeiden University Medical Center, Leiden, The NetherlandsDepartment of MedicineDivision of Endocrinology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pediatric EndocrinologyEmma Children's Hospital, Academic Medical Center, Amsterdam, The NetherlandsEndocrinology and MetabolismAcademic Medical Center, The NetherlandsDevelopmental Biology and Cancer ProgrammeInstitute of Child Health, London, UKDepartment of Pharmacology and TherapeuticsMcGill University, Montreal, Quebec, CanadaCenter for Reproductive MedicineWomen's and Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.

Publikováno v: The Journal of endocrinology [J Endocrinol] 2015 Sep; Vol. 226 (3), pp. 181-91. Date of Electronic Publication: 2015 Jul 10.

Angiotensin II type 2 receptor ligand PD123319 attenuates hyperoxia-induced lung and heart injury at a low dose in newborn rats.

Autor: Wagenaar GT; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands; g.t.m.wagenaar@lumc.nl., Sengers RM; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands;, Laghmani el H; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands;, Chen X; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands;, Lindeboom MP; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands;, Roks AJ; Division of Vascular Disease and Pharmacology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands;, Folkerts G; Department of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands; and., Walther FJ; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands; Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2014 Aug 01; Vol. 307 (3), pp. L261-72. Date of Electronic Publication: 2014 Jun 20.