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Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction – A model for cross-modulation

Autor: Thompson Erik W, Blick Tony, Wafai Razan, Hugo Honor J, Newgreen Donald F

Publikováno v: BMC Cancer, Vol 9, Iss 1, p 235 (2009)

Abstract Background A feature of epithelial to mesenchymal transition (EMT) relevant to tumour dissemination is the reorganization of actin cytoskeleton/focal contacts, influencing cellular ECM adherence and motility. This is coupled with the transcr

Externí odkaz: https://doaj.org/article/04e45ae886cd470c840141ec74c64afd

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Multiplexed tandem polymerase chain reaction identifies strong expression of oestrogen receptor and Her-2 from single, formalin-fixed, paraffin-embedded breast cancer sections

Autor: Thompson, Erik W., Warton, Kristina, Blick, Tony, Wafai, Razan, Hill, Prue, Stanleys, Keith

Publikováno v: In Pathology February 2010 42(2):165-172

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Additional file 7 of Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system

Autor: Wafai, Razan, Williams, Elizabeth D., Souza, Emma De, Simpson, Peter T., Reed, Amy E. McCart, Kutasovic, Jamie R., Waltham, Mark, Snell, Cameron E., Blick, Tony, Thompson, Erik W., Hugo, Honor J.

Additional file 7: Supplementary Fig. 7. Assessment of clinical parameters (Regression Free Survival-RFS, Overall Survival-OS, Distant Metastasis Free Survival-DMFS and Progression Free Survival-PFS) in Luminal A cancers with respect to high versus l

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Additional file 4 of Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system

Additional file 4: Supplementary Fig. 4. A Representative images of CD44 and Masson’s Trichrome for the the ED03 and EDW01 PDXs at the indicated passage numbers. The numbers of xenografts examined at various passage numbers are as follows: for ED03

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Additional file 5 of Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system

Additional file 5: Supplementary Fig. 5. Image J-based quantification of relative intensity per cell of IHC targets that displayed the greatest visual change between PDXs and across passages 3 to 7 for both PDXs: CD24 and CD44. Relative intensity per

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Additional file 1 of Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system

Additional file 1: Supplementary Fig. 1. Stromal area in EDW01 tumour cores across serial passaging in mice does not increase. Connective tissue visualised by the Masson’s Trichrome stain, × 4 magnification, scale bar = 200 μM.

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A Rare Case of NUT Carcinoma and Review of the Literature.

Autor: Zelman, Brandon, Chen, Hannah, Pambuccian, Stefan, Massarani-Wafai, Razan, Mehrotra, Swati, Ananthanarayanan, Vijayalakshmi

Publikováno v: AJSP: Reviews & Reports; Jul/Aug2021, Vol. 26 Issue 4, p264-268, 5p

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