Proteomic biomarkers predicting lymph node involvement in serum of cervical cancer patients. Limitations of SELDI-TOF MS

Autor: Van Gorp Toon, Cadron Isabelle, Daemen Anneleen, De Moor Bart, Waelkens Etienne, Vergote Ignace

Publikováno v: Proteome Science, Vol 10, Iss 1, p 41 (2012)

Abstract Background Lymph node status is not part of the staging system for cervical cancer, but provides important information for prognosis and treatment. We investigated whether lymph node status can be predicted with proteomic profiling. Material

Externí odkaz: https://doaj.org/article/32bdf000def94e5badebc9295b1892e3

TRIzol treatment of secretory phase endometrium allows combined proteomic and mRNA microarray analysis of the same sample in women with and without endometriosis

Autor: Gevaert Olivier, Meuleman Christel, Mihalyi Attila, Waelkens Etienne, Kyama Cleophas M, Simsa Peter, Fassbender Amelie, Van de Plas Raf, de Moor Bart, D'Hooghe Thomas M

Publikováno v: Reproductive Biology and Endocrinology, Vol 8, Iss 1, p 123 (2010)

Abstract Background According to mRNA microarray, proteomics and other studies, biological abnormalities of eutopic endometrium (EM) are involved in the pathogenesis of endometriosis, but the relationship between mRNA and protein expression in EM is

Externí odkaz: https://doaj.org/article/f0abf2c14ae142a98de7ec1f2e34997d

Purification, Molecular Cloning, and Expression of 2-Hydroxyphytanoyl-CoA Lyase, a Peroxisomal Thiamine Pyrophosphate-Dependent Enzyme that Catalyzes the Carbon-Carbon Bond Cleavage during α -Oxidation of 3-Methyl-Branched Fatty Acids

Autor: Foulon, Veerle, Antonenkov, Vasily D., Croes, Kathleen, Waelkens, Etienne, Mannaerts, Guy P., Van Veldhoven, Paul P., Casteels, Minne

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1999 Aug . 96(18), 10039-10044.

Externí odkaz: https://www.jstor.org/stable/48690

Excitation energy deactivation funnel in 3-substituted BODIPY-porphyrin conjugate

Autor: Nguyen, Nguyen Tran, Verbelen, Bram, Leen, Volker, Waelkens, Etienne, Dehaen, Wim, Kruk, Mikalai

Publikováno v: In Journal of Luminescence November 2016 179:306-313

FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4

Autor: Crivelli, Simone M, Luo, Qian, Kruining, Daan van, Giovagnoni, Caterina, Mané-Damas, Marina, den Hoedt, Sandra, Berkes, Dusan, De Vries, Helga E, Mulder, Monique T, Walter, Jochen, Waelkens, Etienne, Derua, Rita, Swinnen, Johannes V, Dehairs, Jonas, Wijnands, Erwin P M, Bieberich, Erhard, Losen, Mario, Martinez-Martinez, Pilar

Publikováno v: Biomedicine and Pharmacotherapy, 152:113240. Elsevier Masson
Biomedicine & Pharmacotherapy, 152:113240. Elsevier Masson
Crivelli, S M, Luo, Q, Kruining, D V, Giovagnoni, C, Mané-Damas, M, den Hoedt, S, Berkes, D, De Vries, H E, Mulder, M T, Walter, J, Waelkens, E, Derua, R, Swinnen, J V, Dehairs, J, Wijnands, E P M, Bieberich, E, Losen, M & Martinez-Martinez, P 2022, ' FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4 ', Biomedicine and Pharmacotherapy, vol. 152, 113240, pp. 113240 . https://doi.org/10.1016/j.biopha.2022.113240

The protection mediated by the bioactive sphingolipid sphingosine-1-phosphate (S1P) declines during Alzheimer's disease (AD) progression, especially in patients carrying the apolipoprotein E ε4 (APOE4) isoform. The drug FTY720 mimics S1P bioactivity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94372c593410c51b4547c0939a09af13
https://research.vumc.nl/en/publications/ae57e17b-8ff8-465c-9b2b-7677b089f2fc