Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Wael Traboulsi"'
Autor:
Ahmad Joshkon, Emeline Tabouret, Wael Traboulsi, Richard Bachelier, Stéphanie Simoncini, Sandrine Roffino, Carine Jiguet-Jiglaire, Bassam Badran, Benjamin Guillet, Alexandrine Foucault-Bertaud, Aurelie S. Leroyer, Françoise Dignat-George, Olivier Chinot, Hussein Fayyad-Kazan, Nathalie Bardin, Marcel Blot-Chabaud
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Rationale Glioblastoma multiforme (GBM) is a primary brain tumor with poor prognosis. The U.S. food and drug administration approved the use of the anti-VEGF antibody bevacizumab in recurrent GBM. However, resistance to this treatment is fre
Externí odkaz:
https://doaj.org/article/4d1eae0ff4d841e7be8d966be7f7fe12
Autor:
Deborah Reynaud, Roland Abi Nahed, Nicolas Lemaitre, Pierre-Adrien Bolze, Wael Traboulsi, Frederic Sergent, Christophe Battail, Odile Filhol, Vincent Sapin, Houssine Boufettal, Pascale Hoffmann, Touria Aboussaouira, Padma Murthi, Rima Slim, Mohamed Benharouga, Nadia Alfaidy
Publikováno v:
Cancers, Vol 13, Iss 12, p 2999 (2021)
The inflammatory gene NLRP7 is the major gene responsible for recurrent complete hydatidiform moles (CHM), an abnormal pregnancy that can develop into gestational choriocarcinoma (CC). However, the role of NLRP7 in the development and immune toleranc
Externí odkaz:
https://doaj.org/article/ad4c14b89e444380978098f8f1d9c1d7
Autor:
Deborah Reynaud, Frederic Sergent, Roland Abi Nahed, Wael Traboulsi, Constance Collet, Christel Marquette, Pascale Hoffmann, Gianfranco Balboni, Qun-Yong Zhou, Padma Murthi, Mohamed Benharouga, Nadia Alfaidy
Publikováno v:
Biomedicines, Vol 9, Iss 3, p 309 (2021)
Endocrine gland derived vascular endothelial growth factor (EG-VEGF) is a canonical member of the prokineticin (PROKs) family. It acts via the two G-protein coupled receptors, namely PROKR1 and PROKR2. We have recently demonstrated that EG-VEGF is hi
Externí odkaz:
https://doaj.org/article/a739c847b6624e17adb94e785c356338
Autor:
Ahmad Joshkon, Xavier Heim, Cléa Dubrou, Richard Bachelier, Wael Traboulsi, Jimmy Stalin, Hussein Fayyad-Kazan, Bassam Badran, Alexandrine Foucault-Bertaud, Aurelie S. Leroyer, Nathalie Bardin, Marcel Blot-Chabaud
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 633 (2020)
The fundamental role of cell adhesion molecules in mediating various biological processes as angiogenesis has been well-documented. CD146, an adhesion molecule of the immunoglobulin superfamily, and its soluble form, constitute major players in both
Externí odkaz:
https://doaj.org/article/4e6e117926dd4afd9eca0a82caf5c76f
Autor:
Nadia Alfaidy, Mohamed Benharouga, Jean J. Feige, Touria Aboussaouira, François Mallet, Philippe Sauthier, Aude Salomon, Pierre A. Bolze, Valentina Onnis, Gianfranco Balboni, Qun Y. Zhou, Mohammed Benlahfid, Pascale Hoffmann, Rima Slim, Sophie Brouillet, Houssine Boufettal, Frédéric Sergent, Wael Traboulsi
Supplemental Methods Figure S1: Reports clinical information's about normal pregnant women, patients with complete hydatiform moles or choriocarcinoma. Figure S2: Experimental procedure. Figure S3: Quantification of EG-VEGF PROKR1 and PROKR2 protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b45ec47753a52567d245f1c41698c3
https://doi.org/10.1158/1078-0432.22463115
https://doi.org/10.1158/1078-0432.22463115
Autor:
Nadia Alfaidy, Mohamed Benharouga, Jean J. Feige, Touria Aboussaouira, François Mallet, Philippe Sauthier, Aude Salomon, Pierre A. Bolze, Valentina Onnis, Gianfranco Balboni, Qun Y. Zhou, Mohammed Benlahfid, Pascale Hoffmann, Rima Slim, Sophie Brouillet, Houssine Boufettal, Frédéric Sergent, Wael Traboulsi
Purpose: Choriocarcinoma (CC) is the most malignant gestational trophoblastic disease that often develops from complete hydatidiform moles (CHM). Neither the mechanism of CC development nor its progression is yet characterized. We recently identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077632cc2184064cffcff323422a73b0
https://doi.org/10.1158/1078-0432.c.6525312
https://doi.org/10.1158/1078-0432.c.6525312
Autor:
Ahmad Joshkon, Alexandrine Foucault-Bertaud, Wael Traboulsi, Christophe Demattei, Françoise Dignat-George, Nadia Alfaidy, Richard Bachelier, Odile Paulmyer-Lacroix, Jean-Christophe Gris, Aurélie S. Leroyer, Marcel Blot-Chabaud, Sylvie Bouvier Pharm, V. Letouzey, Nathalie Bardin, Mathieu Fortier, Sandra M. Blois, Marie Nollet, Eve Mousty
Publikováno v:
F&S Science
F&S Science, 2022, 3 (1), pp.84-94. ⟨10.1016/j.xfss.2021.11.002⟩
F&S Science, 2022, 3 (1), pp.84-94. ⟨10.1016/j.xfss.2021.11.002⟩
International audience; Objective: To explore the regulatory role of soluble CD146 (sCD146) and its interaction with galectin-1 (Gal1) in placenta-mediated complications of pregnancy.Design: Prospective pilot and experimental studies.Setting: Univers
Autor:
Wael Traboulsi, Subhadip Kundu, Pankaj Gaur, Zainab Ramlaoui, Dareen Sarhan, Nour Shobaki, Jacob Lee, Nazli Jafarzadeh, Simon T. Barry, Viia E. Valge-Archer, Vivek Verma, Seema Gupta, Samir N. Khleif
Publikováno v:
Cancer Research. 83:LB339-LB339
Olaparib is the most widely studied third-generation PARP inhibitor (PARPi) in clinical practice with a significant clinical outcome in BRCA deficient tumors such as breast and ovarian cancers. However, innate and adaptive resistance in patients with
Autor:
Padma Murthi, Roland Abi Nahed, Deborah Reynaud, Vincent Sapin, Nadia Alfaidy, Christophe Battail, Mohamed Benharouga, Nicolas Lemaitre, Touria Aboussaouira, Pierre-Adrien Bolze, Wael Traboulsi, Rima Slim, Odile Filhol, Pascale Hoffmann, Houssine Boufettal, Frederic Sergent
Publikováno v:
Cancers
Cancers, MDPI, 2021, 13 (12), pp.2999. ⟨10.3390/cancers13122999⟩
Cancers, Vol 13, Iss 2999, p 2999 (2021)
Volume 13
Issue 12
Cancers, 2021, 13 (12), pp.2999. ⟨10.3390/cancers13122999⟩
Cancers, MDPI, 2021, 13 (12), pp.2999. ⟨10.3390/cancers13122999⟩
Cancers, Vol 13, Iss 2999, p 2999 (2021)
Volume 13
Issue 12
Cancers, 2021, 13 (12), pp.2999. ⟨10.3390/cancers13122999⟩
The inflammatory gene NLRP7 is the major gene responsible for recurrent complete hydatidiform moles (CHM), an abnormal pregnancy that can develop into gestational choriocarcinoma (CC). However, the role of NLRP7 in the development and immune toleranc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec21913925c8a0e506007521982ee44
https://hal.archives-ouvertes.fr/hal-03504065
https://hal.archives-ouvertes.fr/hal-03504065
Autor:
Nazli Jafarzadeh, Pankaj Gaur, Dareen Sarhan, Nour Shobaki, Wael Traboulsi, Zainab Ramlaoui, Vivek Verma, Seema Gupta, Samir N. Khleif
Publikováno v:
Cancer Research. 82:LB217-LB217
Growing evidence suggests that hypoxia is one of the most important phenomena of solid tumors that supports tumor progression as well as therapeutic resistance. When T cells infiltrate the tumor microenvironment (TME), they encounter hypoxia and, in