Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Wael Haqawi"'
Autor:
Pratheesh Kumar Poyil, Abdul K. Siraj, Divya Padmaja, Sandeep Kumar Parvathareddy, Saravanan Thangavel, Khadija Alobaisi, Roxanne Diaz, Rafia Begum, Wael Haqawi, Saif S. Al‐Sobhi, Fouad Al‐Dayel, Khawla S. Al‐Kuraya
Publikováno v:
Molecular Oncology, Vol 18, Iss 3, Pp 691-706 (2024)
Polo‐like kinase 1 (PLK1; also known as serine/threonine‐protein kinase PLK1) serves as a central player in cell proliferation, exerting critical regulatory roles in mitotic processes and cell survival. We conducted an analysis of PLK1 protein ex
Externí odkaz:
https://doaj.org/article/57d1afe46d474a6699d90c95cfe8d3a3
Autor:
Rong Bu, Abdul K. Siraj, Maha Al-Rasheed, Kaleem Iqbal, Saud Azam, Zeeshan Qadri, Wael Haqawi, Asma Tulbah, Fouad Al-Dayel, Osama Almalik, Khawla S. Al-Kuraya
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Breast cancer (BC) is the most prevalent malignancy among women worldwide with germline pathogenic variants/likely pathogenic variants (PVs/LPVs) in BRCA1/2 accounting for a large portion of hereditary cases. Recently, heterozygous PVs/LPVs
Externí odkaz:
https://doaj.org/article/0488b7354eda4a4ca492a51ccc846bac
Autor:
Pratheesh Kumar Poyil, Abdul K. Siraj, Divya Padmaja, Sandeep Kumar Parvathareddy, Roxanne Diaz, Saravanan Thangavel, Rafia Begum, Wael Haqawi, Falah Hassan Al‐Mohanna, Saif S. Al‐Sobhi, Fouad Al‐Dayel, Khawla S. Al‐Kuraya
Publikováno v:
Molecular Oncology, Vol 17, Iss 7, Pp 1324-1342 (2023)
Furin belongs to the pro‐protein convertases (PCs) family and its aberrant expression has been documented in various types of cancers; however, its role in thyroid cancer remains unclear. We investigated the expression of furin in a large cohort of
Externí odkaz:
https://doaj.org/article/b58013fb55f74e7cbcb973ffa45504ad
Autor:
Abdul K. Siraj, Rong Bu, Sandeep Kumar Parvathareddy, Kaleem Iqbal, Saud Azam, Zeeshan Qadri, Maha Al-Rasheed, Wael Haqawi, Mark Diaz, Ingrid G. Victoria, Ismail A. Al-Badawi, Asma Tulbah, Fouad Al-Dayel, Dahish Ajarim, Khawla S. Al-Kuraya
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract The PALB2 gene is a breast cancer (BC) and ovarian cancer (OC) predisposition gene involved in the homologous recombination repair pathway. However, the prevalence and clinicopathological association of PALB2 pathogenic/likely pathogenic (PV
Externí odkaz:
https://doaj.org/article/0c97e2f47b824050854ac2fed92effc0
Autor:
Sandeep Kumar Parvathareddy, Abdul K. Siraj, Padmanaban Annaiyappanaidu, Nabil Siraj, Wael Haqawi, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundThe incidence of pediatric differentiated thyroid carcinoma (DTC) is increasing. Despite the advanced disease at presentation, the overall prognosis of DTC in children is excellent. The aim of this study is to investigate the risk stratifyi
Externí odkaz:
https://doaj.org/article/08c9610cd85a43b584e9d94c47189701
Autor:
Rong Bu, Abdul K. Siraj, Sandeep Kumar Parvathareddy, Kaleem Iqbal, Saud Azam, Zeeshan Qadri, Maha Al-Rasheed, Wael Haqawi, Mark Diaz, Khadija Alobaisi, Padmanaban Annaiyappanaidu, Nabil Siraj, Hamed AlHusaini, Osama Alomar, Ismail A. Al-Badawi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12299 (2022)
Lynch syndrome (LS) is the most common cause of inherited endometrial cancer (EC). The prevalence and molecular characteristic of LS in Middle Eastern women with EC have been underexplored. To evaluate the frequency of LS in a cohort of EC patients f
Externí odkaz:
https://doaj.org/article/f9705a84bf8740d191b96cf01ce11f78
Autor:
Rong Bu, Abdul K. Siraj, Tariq Masoodi, Sandeep Kumar Parvathareddy, Kaleem Iqbal, Maha Al-Rasheed, Wael Haqawi, Mark Diaz, Ingrid G. Victoria, Saud M. Aldughaither, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Mitogen-activated protein kinase kinase 1 (MAP2K1) is a dual specificity protein kinase that phosphorylates both threonine and tyrosine residues in ERK. MAP2K1 mutations have been identified in several cancers. However, their role in Middle Eastern p
Externí odkaz:
https://doaj.org/article/f157ad0be48f4d4493b2553807f46b9b
Autor:
Abdul K. Siraj, Sandeep Kumar Parvathareddy, Padmanaban Annaiyappanaidu, Wael Haqawi, Maha Al-Rasheed, Hadeel M. AlManea, Hussah F. AlHussaini, Fouad Al-Dayel, Khawla S. Al-Kuraya
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 2, p 73 (2021)
Several clinical trials are investigating the use of immune-targeted therapy with Programmed death ligand-1 (PD-L1) inhibitors for colorectal cancer (CRC), with promising results for patients with mismatch repair (MMR) deficiency or metastatic CRC. H
Externí odkaz:
https://doaj.org/article/9d02eb70a29c4a158ac7f7ccd989e149
Autor:
Pratheesh Kumar Poyil, Abdul K. Siraj, Divya Padmaja, Sandeep Kumar Parvathareddy, Roxanne Diaz, Saravanan Thangavel, Rafia Begum, Wael Haqawi, Falah Hassan Al‐Mohanna, Saif S. Al‐Sobhi, Fouad Al‐Dayel, Khawla S. Al‐Kuraya
Publikováno v:
Molecular Oncology.
Autor:
null Poyil Pratheesh Kumar, null Abdul K. Siraj, null Divya Padmaja, null Sandeep Kumar Parvathareddy, null Roxanne Diaz, null Saravanan Thangavel, null Rafia Begum, null Wael Haqawi, null Falah Hassan Al‐Mohanna, null Saif S. Al‐Sobhi, null Fouad Al‐Dayel, null Khawla S. Al‐Kuraya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dc766e3ac0a810e500c586fa48a7c42
https://doi.org/10.1002/1878-0261.13396/v2/response1
https://doi.org/10.1002/1878-0261.13396/v2/response1