Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Wael Eldahshan"'
Autor:
Abdelrahman Y. Fouda, Wael Eldahshan, S. Priya Narayanan, R. William Caldwell, Ruth B. Caldwell
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Ischemic retinopathies represent a major cause of visual impairment and blindness. They include diabetic retinopathy (DR), acute glaucoma, retinopathy of prematurity (ROP), and central (or branch) retinal artery occlusion (CRAO). These conditions sha
Externí odkaz:
https://doaj.org/article/498efde81b864c29aa0c6bf98cfd1b7e
Autor:
Heba A. Ahmed, Tauheed Ishrat, Bindu Pillai, Abdelrahman Y. Fouda, Mohammed A. Sayed, Wael Eldahshan, Jennifer L. Waller, Adviye Ergul, Susan C. Fagan
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-16 (2018)
Abstract Background With the aging population, the prevalence and incidence of cerebrovascular disease will continue to rise, as well as the number of individuals with vascular cognitive impairment/dementia (VCID). No specific FDA-approved treatments
Externí odkaz:
https://doaj.org/article/656ea8b917cd41a0b5dede0fe73be8f9
Autor:
LaDonya Jackson-Cowan, Wael Eldahshan, Selin Dumanli, Guangkuo Dong, Sarah Jamil, Yasir Abdul, Waleed Althomali, Babak Baban, Susan C. Fagan, Adviye Ergul
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1356 (2021)
About 70% of stroke victims present with comorbid diseases such as diabetes and hypertension. The integration of comorbidities in pre-clinical experimental design is important in understanding the mechanisms involved in the development of stroke inju
Externí odkaz:
https://doaj.org/article/3f4c0da3dbb14996b2b6325251cfb2f8
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 876 (2018)
For many years, modulators of the renin angiotensin system (RAS) have been trusted by clinicians for the control of essential hypertension. It was recently demonstrated that these modulators have other pleiotropic properties independent of their hypo
Externí odkaz:
https://doaj.org/article/f907b8fc740e499f955db00c61a65549
Publikováno v:
Translational Stroke Research
The COVID-19 pandemic is associated with neurological symptoms and complications including stroke. There is hypercoagulability associated with COVID-19 that is likely a "sepsis-induced coagulopathy" and may predispose to stroke. The SARS-CoV-2 virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4e50da0f4752ab1b46e3ac382a1e3e
http://europepmc.org/articles/PMC7202903
http://europepmc.org/articles/PMC7202903
Autor:
Maribeth H. Johnson, Adviye Ergul, Waleed Althomali, Ladonya Jackson, Susan C. Fagan, Wael Eldahshan, Babak Baban, Jessica A. Filosa, Mohammed A. Sayed, Guangkuo Dong
Publikováno v:
Transl Stroke Res
INTRODUCTION: A disabling consequence of stroke is cognitive impairment, occurring in 12%–48% of patients, for which there is no therapy. A critical barrier is the lack of understanding of how post-stroke cognitive impairment (PSCI) develops. While
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1766dc3e1b4d775f801865d017a7ec68
https://doi.org/10.1007/s12975-019-00752-5
https://doi.org/10.1007/s12975-019-00752-5
Autor:
Ammar A. Abdelrahman, Wael Eldahshan, R. William Caldwell, Zhimin Xu, Paul Ning-Man Cheng, Syed Ah. Zaidi, Abdelrahman Y. Fouda, Tahira Lemtalsi, Esraa Shosha, Ruth B. Caldwell, S. Priya Narayanan
Publikováno v:
Exp Neurol
Arginase 1 (A1) is the enzyme that hydrolyzes the amino acid, L-arginine, to ornithine and urea. We have previously shown that A1 deletion worsens retinal ischemic injury, suggesting a protective role of A1. In this translational study, we aimed to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56559a73ba7f7b60382a7ee3564fff6d
https://europepmc.org/articles/PMC9122100/
https://europepmc.org/articles/PMC9122100/
Autor:
Mohamed E. Awad, Abdulkarim Alshammari, Susan C. Fagan, Heba A. Ahmed, Ellen E. Gillis, Waleed Althomali, Mohammed E. Elsalanty, Adviye Ergul, Mohammed A. Sayed, Marion A. Cooley, Ladonya Jackson, Guangkuo Dong, Wael Eldahshan, Jennifer C. Sullivan, Bindu Pillai
Publikováno v:
Vascul Pharmacol
Angiotensin signaling is known to be sexually dimorphic. Although it is a well-studied target for intervention in stroke and cognitive impairment, female studies are rare. With females suffering a disproportionately greater negative impact of stroke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb521a063cfa418d68200d58f38728f
https://pubmed.ncbi.nlm.nih.gov/34481068
https://pubmed.ncbi.nlm.nih.gov/34481068
Autor:
Wael Eldahshan, Waleed Althomali, Mohammed A. Sayed, Bindu Pillai, Adviye Ergul, Maribeth H. Johnson, Susan C. Fagan, Mahmoud Abdelbary, Ali S. Arbab
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Post-stroke cognitive impairment (PSCI) is a major source of disability, affecting up to two thirds of stroke survivors with no available therapeutic options. The condition remains understudied in preclinical models due to its delayed presentation. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddbbe0c74ec255acb6845d9bdf456b0
https://doi.org/10.1038/s41598-020-75450-6
https://doi.org/10.1038/s41598-020-75450-6
Autor:
Sarah Jamil, Ladonya Jackson, Guangkuo Dong, Wael Eldahshan, Selin Dumanli, Babak Baban, Susan C. Fagan, Adviye Ergul
Publikováno v:
Stroke. 51
Post-stroke cognitive impairment (PSCI) occurs in up to 48% of patients, for which there is no therapy. Although 70% of stroke victims present with comorbid diseases such as diabetes and hypertension, the inadequate integration of these comorbidities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e71233ce72333361a69951f106d8527e
https://doi.org/10.1161/str.51.suppl_1.wp155
https://doi.org/10.1161/str.51.suppl_1.wp155