A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults

Autor: Ostergaard, L., Vesikari, T., Absalon, J., Beeslaar, J., Ward, B. J., Senders, S., Eiden, J. J., Jansen, K. U., Anderson, A. S., York, L. J., Jones, T. R., Harris, S. L., O'Neill, R., Radley, D., Maansson, R., Pregaldien, J. -L., Ginis, J., Staerke, N. B., Perez, J. L., Belle-Isle, J, Elfassi, E, Fredette, P, Garfield, H, Girard, G, Lachance, P, Adamkova, E, Bartonova, E, Drazan, D, Dvorakova, J, Kosina, P, Kyjonkova, A, Ruzkova, R, Vitousova, E, Ahonen, A, Forsten, A, Karppa, T, Kokko, S, Lagerstrom-Tirri, Pm, Simila, Jk, Adelt, T, Behre, U, Schwarz, Tf, Castiglia, P, Esposito, S, Ferrera, G, Icardi, G, Brzostek, J, Hasiec, B, Konior, R, Pejcz, J, Szymanski, H, Witor, A, Faust, Sn, Finn, Ah, Heath, Pt, Pollard, Aj, Altamirano, Dd, Ashley CT Jr, Bader, Gf, Bauer GH Jr, Block SL Jr, Brandon, Dm, Davis, Mg, Devalle, O, Egelhof, Rh, Essink, Bj, Fouch, Bb, Fox, Bp, Franklin, Er, Garscadden, Ag, Goswami, Up, Gregory, Dm, Helman, Ll, Houchin, Vg, Howard, Ce, Johnson, Ad, Johnston WH Jr, Jordan, Ca, Kimmel, Ma, Klein, Tr, Krilov, Lr, Labarbera, Ap, Labuda JM II, Latiolais, Tg, Lello, Lg, Lewis, Dh, Ley, Ja, London, Al, Martin, Ms, Mcguire, Mr, Mosteller, Vc, Naccarato, Tr, Nassim, Cg, Rey, Mr, Robbins, Ra, Rouse, Kg, Schear, Mj, Senders, Sd, Shepard, Js, Simpson, Mw, Slandzicki, Aj, Slechta, Sb, Tetrick, Ll, Varman, M, Wadsworth LT III, Ware, Db, White, Jh, Wisman PP Jr, Blouin, F, Dionne, M, Dzongowski, P, Heaton, Kj, Langley, Jm, O'Mahony, Mfj, Powell, Cn, Ward, Bj, Ostergaard, Lj, Haapaniemi, Tl, Paassilta, M, Volanen, Ik, Lepich, T, Smukalska, E, Tarczon, I, Tetiurka, Bm, Domingo, Jd, Morato, Av, Riera, Mt, Sanchez, Ca, Torrell, Jmr, Blumenau, J, Campbell, Ng, Cervantes, Ja, Douglas, Wg, Ensz, Dj, Ervin, Je, Fiel, Tc, Fragoso, Vg, Fried, Dl, Gleason, Gp, Green, Sl, Haggag, Az, Johnson, Ct, Khaira, Rs, Kirstein, Jl, Kravitz, Ae, Lederman, Sn, Marcadis, I, Miller, Ve, Moretti, Jm, Pragalos, Aa, Puopolo, Ad, Rubino, J, Seiden, Dj, Sharp, Sc, Sheldon, Ea, Shockey, Gr, Smith, Wb, Stringer, Jc, Strout, Cb, Studdard, He, Tresser, Njl.

Publikováno v: Ostergaard, L, Vesikari, T, Absalon, J, Beeslaar, J, Ward, B J, Senders, S, Eiden, J J, Jansen, K U, Anderson, A S, York, L J, Jones, T R, Harris, S L, O'Neill, R, Radley, D, Maansson, R, Prégaldien, J-L, Ginis, J, Staerke, N B, Perez, J L & B1971009 and B1971016 Trial Investigators 2017, ' A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults ', The New England Journal of Medicine, vol. 377, no. 24, pp. 2349-2362 . https://doi.org/10.1056/NEJMoa1614474

BACKGROUND: MenB-FHbp is a licensed meningococcal B vaccine targeting factor H-binding protein. Two phase 3 studies assessed the safety of the vaccine and its immunogenicity against diverse strains of group B meningococcus.METHODS: We randomly assign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1121172935bc884479a6f09f24ec94
https://doi.org/10.1056/nejmoa1614474

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Safety and immunogenicity of mRNA-based seasonal influenza vaccines formulated to include multiple A/H3N2 strains with or without the B/Yamagata strain in US adults aged 50-75 years: a phase 1/2, open-label, randomised trial.

Autor: Hsu D; Moderna, Cambridge, MA, USA. Electronic address: denise.hsu@modernatx.com., Jayaraman A; Moderna, Cambridge, MA, USA., Pucci A; Moderna, Cambridge, MA, USA., Joshi R; Moderna, Cambridge, MA, USA., Mancini K; Moderna, Cambridge, MA, USA., Chen HL; Moderna, Cambridge, MA, USA., Koslovsky K; Moderna, Cambridge, MA, USA., Mao X; Moderna, Cambridge, MA, USA., Choi A; Moderna, Cambridge, MA, USA., Henry C; Moderna, Cambridge, MA, USA., Vakil J; Moderna, Cambridge, MA, USA., Stadlbauer D; Moderna, Cambridge, MA, USA., Jorquera P; Moderna, Cambridge, MA, USA., Arunkumar GA; Moderna, Cambridge, MA, USA., Sanchez-Crespo NE; Research Center of America, Hollywood, FL, USA., Wadsworth LT; Sundance Clinical Research, St Louis, MO, USA., Bhupathy V; Long Beach Research Institute, Long Beach, CA, USA., Du E; Moderna, Cambridge, MA, USA., Avanesov A; Moderna, Cambridge, MA, USA., Ananworanich J; Moderna, Cambridge, MA, USA., Nachbagauer R; Moderna, Cambridge, MA, USA.

Publikováno v: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Sep 05. Date of Electronic Publication: 2024 Sep 05.