Zobrazeno 1 - 10
of 2 998
pro vyhledávání: '"Wadih A"'
Autor:
Alexander M. Ille, Christopher Markosian, Stephen K. Burley, Michael B. Mathews, Renata Pasqualini, Wadih Arap
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Natural language-based generative artificial intelligence (AI) has become increasingly prevalent in scientific research. Intriguingly, capabilities of generative pre-trained transformer (GPT) language models beyond the scope of natural langu
Externí odkaz:
https://doaj.org/article/10e11cbd36b74d4f8c9029d6d1ab1092
Autor:
Weslley S. Andrade, Fenny H. F. Tang, Antonio C. H. Mariotti, Marilia W. Mancini, Ivison X. Duarte, Eric A. Singer, Robert E. Weiss, Renata Pasqualini, Wadih Arap, Marco A. Arap
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Kidney cancer is a common urologic malignancy with either laparoscopic (LPN) or robotic partial nephrectomy as therapeutic options of choice for localized tumors. However, renal resection and suturing are challenging steps of the procedure t
Externí odkaz:
https://doaj.org/article/1404ef4d52ad4867be39377ed33faf1d
Autor:
Matthieu Groh, Julien Rohmer, Nicolas Etienne, Wadih Abou Chahla, Antoine Baudet, Aurélie Chan Hew Wai, Cécile Chenivesse, Irena Clisson Rusek, Vincent Cottin, Matthieu Decamp, Pascal De Groote, Fanny Delahousse, Nicolas Duployez, Stanislas Faguer, Frédéric Gottrand, Florent Huang, Thierry Leblanc, Antoine Magnan, Thierry Martin, Geoffrey Mortuaire, Antoine Néel, Luc Paris, Arnaud Petit, Julien Rossignol, Nicolas Schleinitz, Juliette Soret-Dulphy, Delphine Staumont-Salle, Benjamin Terrier, Louis Terriou, Jean-François Viallard, Guillaume Lefèvre, Jean-Emmanuel Kahn
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-35 (2023)
Abstract Eosinophilic-related clinical manifestations are protean and the underlying conditions underpinning eosinophilia are highly diverse. The etiological workup of unexplained eosinophilia/hypereosinophilia can be challenging, and can lead someti
Externí odkaz:
https://doaj.org/article/1286a876df1e46fea03f30a2bd0da951
Autor:
Chloé Arfeuille, Yoann Vial, Margaux Cadenet, Aurélie Caye-Eude, Odile Fenneteau, Quentin Neven, Adeline A Bonnard, Simone Pizzi, Giovanna Carpentieri, Yline Capri, Katia Girardi, Lucia Pedace, Marina Macchiaiolo, Kamel Boudhar, Monia ben Khaled, Wadih Abou Chahla, Anne Lutun, Mony Fahd, Séverine Drunat, Elisabetta Flex, Jean-Hugues Dalle, Marion Strullu, Franco Locatelli, Marco Tartaglia, Hélène Cavé
Publikováno v:
Haematologica, Vol 999, Iss 1 (2023)
Juvenile myelomonocytic leukemia (JMML) is a rare, generally aggressive myeloproliferative neoplasm affecting young children. It is characterized by granulomonocytic expansion, with monocytosis infiltrating peripheral tissues. JMML is initiated by mu
Externí odkaz:
https://doaj.org/article/65e8c5154d52490e9ade2007b367450e
Autor:
Prashant Dogra, Carmine Schiavone, Zhihui Wang, Javier Ruiz-Ramírez, Sergio Caserta, Daniela I. Staquicini, Christopher Markosian, Jin Wang, H. Dirk Sostman, Renata Pasqualini, Wadih Arap, Vittorio Cristini
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
While the development of different vaccines slowed the dissemination of SARS-CoV-2, the occurrence of breakthrough infections has continued to fuel the COVID-19 pandemic. To secure at least partial protection in the majority of the population through
Externí odkaz:
https://doaj.org/article/a4a1cadac5a342918131500fc17f610e
Autor:
Joseph H. Lubin, Christopher Markosian, D. Balamurugan, Minh T. Ma, Chih-Hsiung Chen, Dongfang Liu, Renata Pasqualini, Wadih Arap, Stephen K. Burley, Sagar D. Khare
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Given the COVID-19 pandemic, there is interest in understanding ligand-receptor features and targeted antibody-binding attributes against emerging SARS-CoV-2 variants. Here, we developed a large-scale structure-based pipeline for analysis of protein-
Externí odkaz:
https://doaj.org/article/dc31889fa8f7403f837661ab04c09d04
Autor:
Eduardo Cararo Lopes, Akshada Sawant, Dirk Moore, Hua Ke, Fuqian Shi, Saurabh Laddha, Ying Chen, Anchal Sharma, Jake Naumann, Jessie Yanxiang Guo, Maria Gomez, Maria Ibrahim, Tracey L. Smith, Gregory M. Riedlinger, Edmund C. Lattime, Stanley Trooskin, Shridar Ganesan, Xiaoyang Su, Renata Pasqualini, Wadih Arap, Subhajyoti De, Chang S. Chan, Eileen White
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 6, Pp n/a-n/a (2023)
Abstract Background Differentiated thyroid cancer (DTC) affects thousands of lives worldwide each year. Typically, DTC is a treatable disease with a good prognosis. Yet, some patients are subjected to partial or total thyroidectomy and radioiodine th
Externí odkaz:
https://doaj.org/article/ec7a07680de6468dbc8e44b77ccb4981
Autor:
Richard C Lauer, Marc Barry, Tracey L Smith, Andrew Maltez Thomas, Jin Wu, Ruofei Du, Ji-Hyun Lee, Arpit Rao, Andrey S Dobroff, Marco A Arap, Diana N Nunes, Israel T Silva, Emmanuel Dias-Neto, Isan Chen, Dennis J McCance, Webster K Cavenee, Renata Pasqualini, Wadih Arap
Publikováno v:
eLife, Vol 12 (2023)
Background: We have previously shown that the long non-coding (lnc)RNA prostate cancer associated 3 (PCA3; formerly prostate cancer antigen 3) functions as a trans-dominant negative oncogene by targeting the previously unrecognized prostate cancer su
Externí odkaz:
https://doaj.org/article/54de7b4374ee4770b8c53468739cf642
Autor:
Eunice W.M. Chin, Qi Ma, Hongyu Ruan, Camille Chin, Aditya Somasundaram, Chunling Zhang, Chunyu Liu, Martin D. Lewis, Melissa White, Tracey L. Smith, Malcolm Battersby, Wei-Dong Yao, Xin-Yun Lu, Wadih Arap, Julio Licinio, Ma-Li Wong
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
Synaptic dysfunction is a manifestation of several neurobehavioral and neurological disorders. A major therapeutic challenge lies in uncovering the upstream regulatory factors controlling synaptic processes. Plant homeodomain (PHD) finger proteins ar
Externí odkaz:
https://doaj.org/article/d81390da89e0491ca883d1a0e915b4cc
Autor:
Montaser F Shaheen, Julie Y Tse, Ethan S Sokol, Margaret Masterson, Pranshu Bansal, Ian Rabinowitz, Christy A Tarleton, Andrey S Dobroff, Tracey L Smith, Thèrése J Bocklage, Brian K Mannakee, Ryan N Gutenkunst, Joyce Bischoff, Scott A Ness, Gregory M Riedlinger, Roman Groisberg, Renata Pasqualini, Shridar Ganesan, Wadih Arap
Publikováno v:
eLife, Vol 11 (2022)
Background: Lymphatic malformations (LMs) often pose treatment challenges due to a large size or a critical location that could lead to disfigurement, and there are no standardized treatment approaches for either refractory or unresectable cases. Met
Externí odkaz:
https://doaj.org/article/c6163aac82254054b261cfba4ae2852f