A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells.

Autor: Castillejo-López C; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, 751 08 , Uppsala, Sweden, Box 815, Husargatan 3, BMC., Bárcenas-Walls JR; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, 751 08 , Uppsala, Sweden, Box 815, Husargatan 3, BMC., Cavalli M; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, 751 08 , Uppsala, Sweden, Box 815, Husargatan 3, BMC., Larsson A; Department of Medical Sciences, Clinical Chemistry, Uppsala University Hospital, 751 85, Uppsala, Sweden., Wadelius C; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, 751 08 , Uppsala, Sweden, Box 815, Husargatan 3, BMC. claes.wadelius@igp.uu.se.

Publikováno v: Lipids in health and disease [Lipids Health Dis] 2024 Feb 16; Vol. 23 (1), pp. 48. Date of Electronic Publication: 2024 Feb 16.

Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Autor: Carlevaro-Fita J., Lanzos A., Feuerbach L., Hong C., Mas-Ponte D., Pedersen J. S., Abascal F., Amin S. B., Bader G. D., Barenboim J., Beroukhim R., Bertl J., Boroevich K. A., Brunak S., Campbell P. J., Chakravarty D., Chan C. W. Y., Chen K., Choi J. K., Deu-Pons J., Dhingra P., Diamanti K., Fink J. L., Fonseca N. A., Frigola J., Gambacorti Passerini C., Garsed D. W., Gerstein M., Getz G., Gonzalez-Perez A., Guo Q., Gut I. G., Haan D., Hamilton M. P., Haradhvala N. J., Harmanci A. O., Helmy M., Herrmann C., Hess J. M., Hobolth A., Hodzic E., Hornshoj H., Isaev K., Izarzugaza J. M. G., Johnson R., Johnson T. A., Juul M., Juul R. I., Kahles A., Kahraman A., Kellis M., Khurana E., Kim J., Kim J. K., Kim Y., Komorowski J., Korbel J. O., Kumar S., Larsson E., Lawrence M. S., Lee D., Lehmann K. -V., Li S., Li X., Lin Z., Liu E. M., Lochovsky L., Lou S., Madsen T., Marchal K., Martincorena I., Martinez-Fundichely A., Maruvka Y. E., McGillivray P. D., Meyerson W., Muinos F., Mularoni L., Nakagawa H., Nielsen M. M., Paczkowska M., Park K., Pich O., Pons T., Pulido-Tamayo S., Raphael B. J., Reimand J., Reyes-Salazar I., Reyna M. A., Rheinbay E., Rubin M. A., Rubio-Perez C., Sabarinathan R., Sahinalp S. C., Saksena G., Salichos L., Sander C., Schumacher S. E., Shackleton M., Shapira O., Shen C., Shrestha R., Shuai S., Sidiropoulos N., Sieverling L., Sinnott-Armstrong N., Stein L. D., Stuart J. M., Tamborero D., Tiao G., Tsunoda T., Umer H. M., Uuskula-Reimand L., Valencia A., Vazquez M., Verbeke L. P. C., Wadelius C., Wadi L., Wang J., Warrell J., Waszak S. M., Weischenfeldt J., Wheeler D. A., Wu G., Yu J., Zhang J., Zhang X., Zhang Y., Zhao Z., Zou L., von Mering C.

Publikováno v: Carlevaro-Fita, J, Lanzós, A, Feuerbach, L, Hong, C, Mas-Ponte, D, Pedersen, J S, Johnson, R, Sidiropoulos, N, Weischenfeldt, J L & Brunak, S 2020, ' Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis ', Communications Biology, vol. 3, no. 1, 56, pp. 1-16 . https://doi.org/10.1038/s42003-019-0741-7
COMMUNICATIONS BIOLOGY
Communications Biology, 3
Communications Biology, 3 (1)
Communications Biology, Vol 3, Iss 1, Pp 1-16 (2020)
Communications Biology, 3, 1
Communications Biology
Carlevaro-Fita, J, Lanzós, A, Feuerbach, L, Hong, C, Mas-Ponte, D, Pedersen, J S, PCAWG Drivers and Functional Interpretation Group, Johnson, R & PCAWG Consortium 2020, ' Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis ', Communications Biology, vol. 3, no. 1, 56 . https://doi.org/10.1038/s42003-019-0741-7
Carlevaro Fita, Joana; Lanzós, Andrés; Feuerbach, Lars; Hong, Chen; Mas-Ponte, David; Pedersen, Jakob Skou; Johnson, Rory (2020). Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis. Communications biology, 3(1), p. 56. Springer Nature 10.1038/s42003-019-0741-7

Long non-coding RNAs (lncRNAs) are a growing focus of cancer genomics studies, creating the need for a resource of lncRNAs with validated cancer roles. Furthermore, it remains debated whether mutated lncRNAs can drive tumorigenesis, and whether such

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784ac264a8fb478f6dcf6b4b524cabd9
https://www.repository.cam.ac.uk/handle/1810/317802

Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

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Z., Maruvka Y. E., Mashl R. J., Menzies A., Milovanovic A., Nielsen M. M., Ossowski S., Paramasivam N., Pedersen J. S., Perry M. D., Puiggros M., Raine K. M., Rheinbay E., Royo R., Sahinalp S. C., Sarrafi I., Schlesner M., Simpson J. T., Stebbings L., Stobbe M. D., Teague J. W., Tiao G., Torrents D., Wala J. A., Wang J., Waszak S. M., Weischenfeldt J., Wendl M. C., Werner J., Wu Z., Xue H., Yakneen S., Yamaguchi T. N., Yellapantula V. D., Yung C. K., Zhang J., Aaltonen L. A., Abascal F., Abeshouse A., Aburatani H., Adams D. J., Agrawal N., Ahn K. S., Ahn S. -M., Aikata H., Akdemir K. C., Al-Ahmadie H., Al-Sedairy S. T., Al-Shahrour F., Alawi M., Albert M., Aldape K., Alexandrov L. B., Ally A., Alsop K., Alvarez E. G., Amary F., Amin S. B., Aminou B., Ammerpohl O., Anderson M. J., Ang Y., Antonello D., Aparicio S., Appelbaum E. L., Arai Y., Aretz A., Arihiro K., Ariizumi S. -I., Armenia J., Arnould L., Asa S., Assenov Y., Atwal G., Aukema S., Auman J. T., Aure M. 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Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature communications, vol 11, iss 1

Weitere Nicht-UDE-Autoren sind nicht genannt. Originalpublikation: 10.1038/s41467-020-18151-y. CA extern The original version of this Article omitted from the author list the 9th author Yize Li, who is from the ‘The McDonnell Genome Institute at Wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a5f62c8099f02a9addd94129605a52
https://www.ncbi.nlm.nih.gov/pubmed/33257764

Sex differences in oncogenic mutational processes

Autor: Li C. H., Prokopec S. D., Sun R. X., Yousif F., Schmitz N., Al-Shahrour F., Atwal G., Bailey P. J., Biankin A. V., Boutros P. C., Campbell P. J., Chang D. K., Cooke S. L., Deshpande V., Faltas B. M., Faquin W. C., Garraway L., Getz G., Grimmond S. M., Haider S., Hoadley K. A., Jiao W., Kaiser V. B., Karlic R., Kato M., Kubler K., Lazar A. J., Louis D. N., Margolin A., Martin S., Nahal-Bose H. K., Nielsen G. P., Nik-Zainal S., Omberg L., P'ng C., Perry M. D., Polak P., Rheinbay E., Rubin M. A., Semple C. A., Sgroi D. C., Shibata T., Siebert R., Smith J., Stein L. D., Stobbe M. D., Thai K., Wright D. W., Wu C. -L., Yuan K., Zhang J., Aaltonen L. A., Abascal F., Abeshouse A., Aburatani H., Adams D. J., Agrawal N., Ahn K. S., Ahn S. -M., Aikata H., Akbani R., Akdemir K. C., Al-Ahmadie H., Al-Sedairy S. T., Alawi M., Albert M., Aldape K., Alexandrov L. B., Ally A., Alsop K., Alvarez E. G., Amary F., Amin S. B., Aminou B., Ammerpohl O., Anderson M. J., Ang Y., Antonello D., Anur P., Aparicio S., Appelbaum E. L., Arai Y., Aretz A., Arihiro K., Ariizumi S. -I., Armenia J., Arnould L., Asa S., Assenov Y., Aukema S., Auman J. T., Aure M. R., Awadalla P., Aymerich M., Bader G. D., Baez-Ortega A., Bailey M. H., Balasundaram M., Balu S., Bandopadhayay P., Banks R. E., Barbi S., Barbour A. P., Barenboim J., Barnholtz-Sloan J., Barr H., Barrera E., Bartlett J., Bartolome J., Bassi C., Bathe O. F., Baumhoer D., Bavi P., Baylin S. B., Bazant W., Beardsmore D., Beck T. A., Behjati S., Behren A., Niu B., Bell C., Beltran S., Benz C., Berchuck A., Bergmann A. K., Bergstrom E. N., Berman B. P., Berney D. M., Bernhart S. H., Beroukhim R., Berrios M., Bersani S., Bertl J., Betancourt M., Bhandari V., Bhosle S. G., Bieg M., Bigner D., Binder H., Birney E., Birrer M., Biswas N. K., Bjerkehagen B., Bodenheimer T., Boice L., Bonizzato G., De Bono J. S., Boot A., Bootwalla M. S., Borg A., Borkhardt A., Boroevich K. A., Borozan I., Borst C., Bosenberg M., Bosio M., Boultwood J., Bourque G., Bova G. S., Bowen D. T., Bowlby R., Bowtell D. D. L., Boyault S., Boyce R., Boyd J., Brazma A., Brennan P., Brewer D. S., Brinkman A. B., Bristow R. G., Broaddus R. R., Brock J. E., Brock M., Broeks A., Brooks A. N., Brooks D., Brors B., Brunak S., Bruxner T. J. C., Bruzos A. L., Buchanan A., Buchhalter I., Buchholz C., Bullman S., Burke H., Burkhardt B., Burns K. H., Busanovich J., Bustamante C. D., Butler A. P., Butte A. J., Byrne N. J., Borresen-Dale A. -L., Caesar-Johnson S. J., Cafferkey A., Cahill D., Calabrese C., Caldas C., Calvo F., Camacho N., Campo E., Cantu C., Cao S., Carey T. E., Carlevaro-Fita J., Carlsen R., Cataldo I., Cazzola M., Cebon J., Cerfolio R., Chadwick D. E., Chakravarty D., Chalmers D., Chan C. W. Y., Chan K., Chan-Seng-Yue M., Chandan V. S., Chanock S. J., Chantrill L. A., Chateigner A., Chatterjee N., Chayama K., Chen H. -W., Chen J., Chen K., Chen Y., Chen Z., Cherniack A. 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T., Drapkin R., Drechsel O., Drews R. M., Serge S., Dudderidge T., Dueso-Barroso A., Dunford A. J., Dunn M., Dursi L. J., Duthie F. R., Dutton-Regester K., Eagles J., Easton D. F., Edmonds S., Edwards P. A., Edwards S. E., Eeles R. A., Ehinger A., Eils J., Eils R., El-Naggar A., Eldridge M., Ellrott K., Erkek S., Escaramis G., Espiritu S. M. G., Estivill X., Etemadmoghadam D., Eyfjord J. E., Fan D., Fan Y., Farcas C., Fassan M., Fatima A., Favero F., Fayzullaev N., Felau I., Fereday S., Ferguson M. L., Ferretti V., Feuerbach L., Field M. A., Fink J. L., Finocchiaro G., Fisher C., Fittall M. W., Fitzgerald A., Fitzgerald R. C., Flanagan A. M., Fleshner N. E., Flicek P., Foekens J. A., Fong K. M., Fonseca N. A., Foster C. S., Fox N. S., Fraser M., Frazer S., Frenkel-Morgenstern M., Friedman W., Frigola J., Fronick C. C., Fujimoto A., Fujita M., Fukayama M., Fulton L. A., Fulton R. S., Furuta M., Futreal P. A., Fullgrabe A., Gabriel S. B., Gallinger S., Gambacorti Passerini C., Gao J., Gao S., Garred O., Garrison E., Garsed D. W., Gehlenborg N., Gelpi J. L. L., George J., Gerhard D. S., Gerhauser C., Gershenwald J. E., Gerstein M., Gerstung M., Ghori M., Ghossein R., Giama N. H., Gibbs R. A., Gill A. J., Gill P., Giri D. D., Glodzik D., Gnanapragasam V. J., Goebler M. E., Goldman M. J., Gomez C., Gonzalez S., Gonzalez-Perez A., Gordenin D. A., Gossage J., Gotoh K., Govindan R., Grabau D., Graham J. S., Grant R. C., Green A. R., Green E., Greger L., Grehan N., Grimaldi S., Grossman R. L., Grundhoff A., Gundem G., Guo Q., Gupta M., Gupta S., Gut I. G., Gut M., Goke J., Ha G., Haake A., Haan D., Haas S., Haase K., Haber J. E., Habermann N., Hach F., Hama N., Hamdy F. C., Hamilton A., Hamilton M. P., Han L., Hanna G. B., Hansmann M., Haradhvala N. J., Harismendy O., Harliwong I., Harmanci A. O., Harrington E., Hasegawa T., Haussler D., Hawkins S., Hayami S., Hayashi S., Hayes D. N., Hayes S. J., Hayward N. 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H., Jang S. J., Jayaseelan J. C., Jayasinghe R., Jefferys S. R., Jegalian K., Jennings J. L., Jeon S. -H., Jerman L., Ji Y., Johansson P. A., Johns A. L., Johns J., Johnson R., Johnson T. A., Jolly C., Joly Y., Jonasson J. G., Jones C. D., Jones D. R., Jones D. T. W., Jones N., Jones S. J. M., Jonkers J., Ju Y. S., Juhl H., Jung J., Juul M., Juul R. I., Juul S., Jager N., Kabbe R., Kahles A., Kahraman A., Kakavand H., Kalimuthu S., von Kalle C., Kang K. J., Karaszi K., Karlan B., Karsch D., Kasaian K., Kassahn K. S., Katai H., Katoh H., Kawakami Y., Kay J. D., Kazakoff S. H., Kazanov M. D., Keays M., Kebebew E., Kefford R. F., Kellis M., Kench J. G., Kennedy C. J., Kerssemakers J. N. A., Khoo D., Khoo V., Khuntikeo N., Khurana E., Kilpinen H., Kim H. K., Kim H. -L., Kim H. -Y., Kim H., Kim J., Kim J. K., Kim Y., King T. A., Klapper W., Kleinheinz K., Klimczak L. J., Knappskog S., Kneba M., Knoppers B. M., Koh Y., Komorowski J., Komura D., Komura M., Kong G., Kool M., Korbel J. O., Korchina V., Korshunov A., Koscher M., Koster R., Kote-Jarai Z., Koures A., Kovacevic M., Kremeyer B., Kretzmer H., Kreuz M., Krishnamurthy S., Kube D., Kumar K., Kumar P., Kumar S., Kumar Y., Kundra R., Kuppers R., Lagergren J., Lai P. H., Laird P. W., Lakhani S. R., Lalansingh C. M., Lalonde E., Lamaze F. C., Lambert A., Lander E., Landgraf P., Landoni L., Langerod A., Lanzos A., Larsimont D., Larsson E., Lathrop M., Lau L. M. S., Lawerenz C., Lawlor R. T., Lawrence M. S., Le X., Lee D., Lee E. A., Lee H. J., Lee J. J. -K., Lee J. -Y., Lee J., Lee M. T. M., Lee-Six H., Lehmann K. -V., Lehrach H., Lenze D., Leonard C. R., Leongamornlert D. A., Leshchiner I., Letourneau L., Letunic I., Levine D. A., Lewis L., Ley T., Li C., Li H. I., Li J., Li L., Li S., Li X., Li Y., Liang H., Liang S. -B., Lichter P., Lin P., Lin Z., Linehan W. M., Lingjaerde O. C., Liu D., Liu E. M., Liu F. -F., Liu F., Liu J., Liu X., Livingstone J., Livitz D., Livni N., Lochovsky L., Loeffler M., Long G. V., Lopez-Guillermo A., Lou S., Lovat L. B., Lu Y., Lu Y. -J., Luchini C., Lungu I., Luo X., Luxton H. J., Lynch A. G., Lype L., Lopez C., Lopez-Otin C., Ma E. Z., Ma Y., MacGrogan G., MacRae S., Macintyre G., Madsen T., Maejima K., Mafficini A., Maglinte D. T., Maitra A., Majumder P. P., Malcovati L., Malikic S., Malleo G., Mann G. J., Mantovani-Loffler L., Marchal K., Marchegiani G., Mardis E. R., Margolin A. A., Marin M. G., Markowetz F., Markowski J., Marks J., Marques-Bonet T., Marra M. A., Marsden L., Martens J. W. M., Martin-Subero J. I., Martincorena I., Martinez-Fundichely A., Maruvka Y. E., Mashl R. J., Massie C. E., Matthew T. J., Matthews L., Mayer E., Mayes S., Mayo M., Mbabaali F., McCune K., McDermott U., McGillivray P. D., McLellan M. D., McPherson J. D., McPherson J. R., McPherson T. A., Meier S. R., Meng A., Meng S., Menzies A., Merrett N. D., Merson S., Meyerson M., Meyerson W., Mieczkowski P. A., Mihaiescu G. L., Mijalkovic S., Mijalkovic-Lazic A. 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Publikováno v: Nature Communications, 11 (1)
Nature communications, vol 11, iss 1
11:4330
Nature Communications
Li, C H, Prokopec, S D, Sun, R X, Yousif, F, Schmitz, N, PCAWG Tumour Subtypes and Clinical Translation, Boutros, P C & PCAWG Consortium 2020, ' Sex differences in oncogenic mutational processes ', Nature Communications, vol. 11, 4330 . https://doi.org/10.1038/s41467-020-17359-2
Nature Communications, 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
Li, Constance H; Prokopec, Stephenie D; Sun, Ren X; Yousif, Fouad; Schmitz, Nathaniel; Boutros, Paul C (2020). Sex differences in oncogenic mutational processes. Nature communications, 11(1), p. 4330. 10.1038/s41467-020-17359-2
RUO. Repositorio Institucional de la Universidad de Oviedo
Nature communications, 11 (1
Nature communications, 11(1):4330. Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications, 11, 1
Li, C H, Prokopec, S D, Sun, R X, Yousif, F, Schmitz, N, Boutros, P C, PCAWG Tumour Subtypes and Clinical Translation & Brunak, S 2020, ' Sex differences in oncogenic mutational processes ', Nature Communications, vol. 11, no. 1, 4330 . https://doi.org/10.1038/s41467-020-17359-2
Nature Communications, Vol 11, Iss 1, Pp 1-24 (2020)
Dipòsit Digital de la UB
Universidad de Barcelona
Li, C H, Prokopec, S D, Sun, R X, Yousif, F, Schmitz, N & Boutros, P C 2020, ' Sex differences in oncogenic mutational processes ', Nat Commun, vol. 11, no. 1, pp. 4330 . https://doi.org/10.1038/s41467-020-17359-2
Nature Communications, 11(1):4330. Nature Publishing Group

Publisher's version (útgefin grein)
Sex differences have been observed in multiple facets of cancer epidemiology, treatment and biology, and in most cancers outside the sex organs. Efforts to link these clinical differences to specific molecula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a728e03fc4c3f01c49f94ad9a871270c
http://hdl.handle.net/11577/3348317

Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Autor: Rheinbay E; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Harvard Medical School, Boston, MA, USA., Nielsen MM; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Abascal F; Wellcome Trust Sanger Institute, Hinxton, UK., Wala JA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA., Shapira O; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Tiao G; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hornshøj H; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Hess JM; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Juul RI; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Lin Z; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard University, Cambridge, MA, USA., Feuerbach L; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sabarinathan R; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Madsen T; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Kim J; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mularoni L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Shuai S; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Lanzós A; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Herrmann C; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Bioquant Center, Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg, Heidelberg, Germany., Maruvka YE; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Shen C; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; cBio Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Amin SB; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX, USA., Bandopadhayay P; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Bertl J; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Boroevich KA; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Busanovich J; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Carlevaro-Fita J; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Chakravarty D; Department of Genitourinary Medical Oncology - Research, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Urology, Icahn school of Medicine at Mount Sinai, New York, NY, USA., Chan CWY; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Craft D; Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA., Dhingra P; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Diamanti K; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Fonseca NA; European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK., Gonzalez-Perez A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Guo Q; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark., Hamilton MP; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Haradhvala NJ; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Hong C; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Isaev K; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Johnson TA; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Juul M; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Kahles A; Division of Computational Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kahraman A; Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland., Kim Y; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Komorowski J; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Institute of Computer Science, Polish Academy of Sciences, Warsaw, Poland., Kumar K; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Kumar S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Lee D; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Lehmann KV; Division of Computational Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Li Y; SBGD Inc, Cambridge, MA, USA.; Department of Haematology, University of Cambridge, Cambridge, UK., Liu EM; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Lochovsky L; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA., Park K; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Pich O; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Roberts ND; Department of Haematology, University of Cambridge, Cambridge, UK., Saksena G; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schumacher SE; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Sidiropoulos N; Biotech Research & Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Sieverling L; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Sinnott-Armstrong N; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Stewart C; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tamborero D; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Tubio JMC; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; The Biomedical Research Centre (CINBIO), Universidade de Vigo, Vigo, Spain., Umer HM; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden., Uusküla-Reimand L; Genetics and Genome Biology Program, SickKids Research Institute, Toronto, Ontario, Canada.; Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia., Wadelius C; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Wadi L; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yao X; New York Genome Center, New York, NY, USA., Zhang CZ; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Zhang J; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Haber JE; Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA, USA., Hobolth A; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark., Imielinski M; New York Genome Center, New York, NY, USA.; Department of Pathology and Laboratory Medicine, and Englander Institute for Precision Medicine, and Institute for Computational Biomedicine, and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Kellis M; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Lawrence MS; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., von Mering C; Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland., Nakagawa H; Laboratory for Cancer Genomics, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan., Raphael BJ; Department of Computer Science, Princeton University, Princeton, NJ, USA., Rubin MA; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Sander C; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; cBio Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Stein LD; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Stuart JM; Center for Biomolecular Science and Engineering, University of California at Santa Cruz, Santa Cruz, CA, USA., Tsunoda T; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.; Laboratory for Medical Science Mathematics, Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Wheeler DA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Johnson R; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Reimand J; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Gerstein M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Department of Computer Science, Yale University, New Haven, CT, USA., Khurana E; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Campbell PJ; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., López-Bigas N; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain., Weischenfeldt J; Biotech Research & Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. joachim.weischenfeldt@bric.ku.dk.; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. joachim.weischenfeldt@bric.ku.dk., Beroukhim R; The Broad Institute of MIT and Harvard, Cambridge, MA, USA. rameen@broadinstitute.org.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA. rameen@broadinstitute.org.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. rameen@broadinstitute.org., Martincorena I; Wellcome Trust Sanger Institute, Hinxton, UK. im3@sanger.ac.uk., Pedersen JS; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark. jakob.skou@clin.au.dk.; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark. jakob.skou@clin.au.dk., Getz G; The Broad Institute of MIT and Harvard, Cambridge, MA, USA. gadgetz@broadinstitute.org.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA. gadgetz@broadinstitute.org.; Harvard Medical School, Boston, MA, USA. gadgetz@broadinstitute.org.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA. gadgetz@broadinstitute.org.

Publikováno v: Nature [Nature] 2023 Feb; Vol. 614 (7948), pp. E40.