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A neural network for classification problems with fuzzy inputs is proposed. A fuzzy input is represented as a LR-type fuzzy set. A generalized pocket algorithm, called fuzzy pocket algorithm, that utilizes LR-type fuzzy sets operations and de
A neural network for classification problems with fuzzy inputs is proposed. A fuzzy input is represented as a LR-type fuzzy set. A generalized pocket algorithm, called fuzzy pocket algorithm, that utilizes LR-type fuzzy sets operations and de
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/69388233479690581464
Autor:
Anthony J. Sinskey, Scott R. Manalis, Vincent Agache, Iris E. Hwang, Jacqueline Wolfrum, Sha Sha, Richard D. Braatz, Wade Wang, Omair A. Karim, Nicole L. McIntosh, Paul W. Barone, Stacy L. Springs, Georgios Katsikis, Vikas Bhat, Bartlomiej J. Blus
Publikováno v:
Nano Letters. 22:1511-1517
Quantifying the composition of viral vectors used in vaccine development and gene therapy is critical for assessing their functionality. Adeno-Associated Virus (AAV) vectors, which are the most widely used viral vectors for in-vivo gene therapy, are
Autor:
Joelle P. Straehla, Paula T. Hammond, Liangliang Hao, Santiago Correa, Natalie Boehnke, Sangeeta N. Bhatia, Wade Wang
Publikováno v:
PMC
Angew Chem Int Ed Engl
Angew Chem Int Ed Engl
Layer-by-layer nanoparticles are modular drug delivery vehicles that incorporate multiple functional materials through sequential deposition of polyelectrolytes onto charged nanoparticle cores. Here, we combined the multicomponent features and tumor
Publikováno v:
Journal of the American Chemical Society. 141:14736-14741
Preparation of an unzipping polyester is reported. The monomer was prepared from benzoic acid in a four-step sequence. Step growth polymerization of the monomer provides the target polymer. Efficient depolymerization upon irradiation at 254 nm was co
Publikováno v:
ACS Nano. 12:6504-6514
The delivery of small interfering RNA (siRNA) remains a major hurdle for the clinical translation of RNA interference (RNAi) therapeutics. Because of its low valency and rigid nature, siRNA typically requires high excesses of cationic delivery materi
Autor:
Wade Wang, Paula T. Hammond
Publikováno v:
Prof. Hammond via Ye Li
For biomaterials, rich functionality often comes at a cost of precise control over structure. In this paper, we have developed a hydrolysis resistant polypeptide that marries the potential for expansive modification with synthetic control. This polym
Autor:
Mariam Ahmed, Akshaya Chandrasekaran, Paula T. Hammond, Nicole Holub, Kevin M. Elias, Wade Wang
Publikováno v:
Cancer Research. 81:1316-1316
Objective: High-grade serous ovarian cancer (HGSOC) is the most common epithelial ovarian cancer subtype. Targeted therapy for HGSOC is challenging as the disease is characterized by copy number variation and not somatic mutations. HGSOC displays wel
Autor:
Linda G. Griffith, Alex J. Wang, Paula T. Hammond, Hongkun He, Caroline C. Ahrens, Wade Wang, Marianna Sofman
Publikováno v:
Biomacromolecules. 21(2)
Expanding the toolkit of modular and functional synthetic material systems for biomimetic extracellular matrices (ECMs) is needed for achieving more predictable and characterizable cell culture. In the present study, we engineered a synthetic hydroge
Publikováno v:
Cancer Research. 80:6241-6241
Objective: High-grade serous ovarian cancer (HGSOC) is the most common epithelial ovarian cancer subtype. Targeted therapy for HGSOC is challenging because the disease is characterized by copy number variation rather than recurrent somatic mutations.
Autor:
Joelle P. Straehla, Wade Wang, Paula T. Hammond, Natalie Boehnke, Sangeeta N. Bhatia, Liangliang Hao, Santiago Correa
Publikováno v:
Angewandte Chemie International Edition. 59:2916-2916