Zobrazeno 1 - 10
of 3 550
pro vyhledávání: '"Wade W"'
Autor:
Samantha C. Lau, Mhamed Grati, Kevin Isgrig, Moaz Sinan, Kaitlyn R. Calabro, Jianliang Zhu, Yasuko Ishibashi, Zeynep Ozgur, Talah Wafa, Inna A. Belyantseva, Tracy Fitzgerald, Thomas B. Friedman, Sanford L. Boye, Shannon E. Boye, Wade W. Chien
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 534-545 (2023)
Usher syndrome is the most common cause of deafness-blindness in the world. Usher syndrome type 1B (USH1B) is associated with mutations in MYO7A. Patients with USH1B experience deafness, blindness, and vestibular dysfunction. In this study, we applie
Externí odkaz:
https://doaj.org/article/ea475ade936f41d5b9fc0d539fc7be4e
Autor:
Robyn T. Domsic, Robin Pokrzywinski, Larissa Stassek, Wade W. Benton, Christa‐Lynn Vampola, Daniel E. Furst, Lorinda Chung, Virginia Steen, Maureen D. Mayes, Ami A. Shah, Jerry A. Molitor, Kelly Oliver, Vivek Nagaraja, Dinesh Khanna
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 3, Pp 132-141 (2023)
Objective To better understand the symptoms and impacts of Raynaud phenomenon (RP) in patients with systemic sclerosis (SSc) and to evaluate the content validity and usability of a new electronic patient‐reported outcome (PRO) measure for RP: the R
Externí odkaz:
https://doaj.org/article/2dd35a0153c940ee986f4d2a8674ad51
Autor:
Kevin Isgrig, Yasuko Ishibashi, Hyun Jae Lee, Jianliang Zhu, Mhamed Grati, Jean Bennett, Andrew J. Griffith, Isabelle Roux, Wade W. Chien
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 371-383 (2022)
Inner ear gene therapy using adeno-associated viruses (AAVs) has been successfully applied to several mouse models of hereditary hearing loss to improve their auditory function. While most inner ear gene therapy studies have focused on the mechanosen
Externí odkaz:
https://doaj.org/article/18c81c1ca47f44779f4c8ee24b6f2199
Publikováno v:
Acta Palaeontologica Polonica, Vol 66, Iss 3, Pp 663-678 (2021)
The middle Marjum Formation is one of five Miaolingian Burgess Shale-type deposits in Utah, USA. It preserves a diverse non-biomineralized fossil assemblage, which is dominated by panarthropods and sponges. Infaunal components are particularly rare,
Externí odkaz:
https://doaj.org/article/93ade7c02a6d42a6982faa490eb810bf
Publikováno v:
World Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 7, Iss 2, Pp 88-93 (2021)
Hypothesis: Three-dimensional (3D) printed temporal bones are comparable to cadaveric temporal bones as a training tool for otologic surgery. Background: Cadaveric temporal bone dissection is an integral part of otology surgical training. Unfortunate
Externí odkaz:
https://doaj.org/article/3a41b4d388a04f029b2ed3f124728428
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 15, Iss 1, Pp 1-8 (2020)
Abstract Background To investigate differences in the tibial tubercle-trochlear groove (TT-TG) and patellar tendon-posterior cruciate ligament (PT-PCL) distances in symptomatic patients with non-contact internal knee derangements (IKD) and symptomati
Externí odkaz:
https://doaj.org/article/4c095576e8eb4720bc7973af94937af7
Autor:
Seyed Hossein Aalaei-Andabili, Ki E. Park, Calvin Y. Choi, Eddie W. Manning, Wade W. Stinson, Ryan Van Woerkom, Thomas Pilgrim, Dharam J. Kumbhani, Anthony A. Bavry
Publikováno v:
Cardiology and Therapy, Vol 9, Iss 1, Pp 201-206 (2020)
Abstract Introduction Lower transcatheter aortic valve replacement (TAVR) pressure gradients have been reported after implantation of self-expanding valves compared with balloon-expandable valves; however, there is a paucity of data on the relationsh
Externí odkaz:
https://doaj.org/article/48f938f496564c89ac24e3c4d7dc344d
Autor:
Janet R. Chao, Parna Chattaraj, Tina Munjal, Keiji Honda, Kelly A. King, Christopher K. Zalewski, Wade W. Chien, Carmen C. Brewer, Andrew J. Griffith
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Recessive mutations of coding regions and splice sites of the SLC26A4 gene cause hearing loss with enlargement of the vestibular aqueduct (EVA). Some patients also have a thyroid iodination defect that can lead to multinodular goi
Externí odkaz:
https://doaj.org/article/a1762e3b69644b61a4f412a1d20d7f56
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Adeno-associated virus is used in gene therapy in mouse models of hearing loss. Here the authors compare vectors and find AAV2.7m8 can infect cells in the inner ear with high efficiency.
Externí odkaz:
https://doaj.org/article/ba8b27d6ee8346729a61ab90b8950373
Autor:
Gregory P. Wilson Mantilla, Stephen G. B. Chester, William A. Clemens, Jason R. Moore, Courtney J. Sprain, Brody T. Hovatter, William S. Mitchell, Wade W. Mans, Roland Mundil, Paul R. Renne
Publikováno v:
Royal Society Open Science, Vol 8, Iss 2 (2021)
Plesiadapiform mammals, as stem primates, are key to understanding the evolutionary and ecological origins of Pan-Primates and Euarchonta. The Purgatoriidae, as the geologically oldest and most primitive known plesiadapiforms and one of the oldest kn
Externí odkaz:
https://doaj.org/article/1774b1f652e04879b785df0a44aad695