Výsledky vyhledávání - "Wade M. Chew"

A Protective Role for Arachidonic Acid Metabolites against Advanced Colorectal Adenoma in a Phase III Trial of Selenium

Autor: Nathan A. Ellis, H-H. Sherry Chow, Meghan B Skiba, Wade M. Chew, Peter Lance, Elizabeth T. Jacobs, Jessica A. Martinez, Kathylynn Saboda

Publikováno v: Nutrients
Volume 13
Issue 11
Nutrients, Vol 13, Iss 3877, p 3877 (2021)

Oxylipins derived from arachidonic acid (ARA) have been implicated in the development of colorectal adenomas and colorectal cancer. The primary purpose of this work was to determine the relationship between plasma levels of oxylipins and colorectal a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab148b2854a83a57b2a2f9239d726a21

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Abstract 2352: Place of birth influences the metabolomic profile and preliminary effectiveness of a weight loss intervention among Hispanic men from the ANIMO pilot study

Autor: H-H. Sherry Chow, David O. Garcia, Melissa Lopez-Pentecost, Jessica A. Martinez, Xiaoxiao Sun, Wade M. Chew, Cynthia A. Thomson

Publikováno v: Cancer Research. 81:2352-2352

Background: The effect of intrinsic and extrinsic factors (e.g. the environment and genetics) on the metabolome may have implications for disease risk, health disparities, and effectiveness of clinical interventions. Purpose: This study investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08a3410ee1fd8cbeea281e3488e4ebc3
https://doi.org/10.1158/1538-7445.am2021-2352

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Lifespan‐extending caloric restriction or m TOR inhibition impair adaptive immunity of old mice by distinct mechanisms

Autor: Jennifer L. Uhrlaub, Emily L. Goldberg, Megan J. Smithey, Kirsten H. Limesand, Melissa J. Romero-Aleshire, Heddwen L. Brooks, Wade M. Chew, Kristin R. Renkema, Melissa S. Ventevogel, Gregory D. Sempowski, Janko Nikolich-Žugich

Publikováno v: Aging Cell

Aging of the world population and a concomitant increase in age-related diseases and disabilities mandates the search for strategies to increase healthspan, the length of time an individual lives healthy and productively. Due to the age-related decli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44332f574abb4d0b2d538fabae9c10f0
https://doi.org/10.1111/acel.12280

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Quantification of cortisol in human eccrine sweat by liquid chromatography - tandem mass spectrometry

Autor: Esther M. Sternberg, Yelena Feinstein, Perry Skeath, Min Jia, Wade M. Chew

Publikováno v: The Analyst. 141(6)

Cortisol has long been recognized as the "stress biomarker" in evaluating stress related disorders. Plasma, urine or saliva are the current source for cortisol analysis. The sampling of these biofluids is either invasive or has reliability problems t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b20888c24d08bac6b2c45c41f21ce2
https://pubmed.ncbi.nlm.nih.gov/26858998

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Effects of Repeated Green Tea Catechin Administration on Human Cytochrome P450 Activity

Autor: James A. Crowell, Min-Jian Xu, David S. Alberts, H-H. Sherry Chow, Chiu Hsieh Hsu, Donna R. Vining, Wade M. Chew, James Ranger-Moore, Iman A. Hakim, Catherine A. Cordova

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 15:2473-2476

Purpose: Preclinical studies suggested that green tea or green tea catechins can modulate the activities of drug-metabolizing enzymes. We conducted this clinical study to determine the effect of repeated green tea catechin administration on human cyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e77a25d951f06491aa7c7914b4db41
https://doi.org/10.1158/1055-9965.epi-06-0365

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Effects of Dosing Condition on the Oral Bioavailability of Green Tea Catechins after Single-Dose Administration of Polyphenon E in Healthy Individuals

Autor: Wade M. Chew, David S. Alberts, James Ranger-Moore, Steven Ross Rodney, Yukihiko Hara, Iman A. Hakim, H-H. Sherry Chow, James A. Crowell, Donna R. Vining, Catherine A. Celaya

Publikováno v: Clinical Cancer Research. 11:4627-4633

Purpose: Green tea has been shown to exhibit cancer-preventive activities in preclinical studies. Its consumption has been associated with decreased risk of certain types of cancers in humans. The oral bioavailability of the major green tea constitue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdb41ab76412235134d9d67043ff0af
https://doi.org/10.1158/1078-0432.ccr-04-2549

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Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice

Autor: Theodore J. Price, Yael Kusne, Nader Sanai, Emily L. Goldberg, Wade M. Chew, Sourav Ghosh, Irina Y. Maskaykina, Heddwen L. Brooks, Kirsten H. Limesand, Sophie M. Hapak, Sara S. Parker, Janko Nikolich-Zugich

Publikováno v: Age (Dordrecht, Netherlands). 36(1)

The chronic and systemic administration of rapamycin extends life span in mammals. Rapamycin is a pharmacological inhibitor of mTOR. Metformin also inhibits mTOR signaling but by activating the upstream kinase AMPK. Here we report the effects of chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723961c5a3a71d46c7c6f28d6d20231f
https://pubmed.ncbi.nlm.nih.gov/23949159

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Resveratrol Modulates Drug and Carcinogen Metabolizing Enzymes in a Healthy Volunteer Study

Autor: David S. Alberts, Chiu Hsieh Hsu, Jessica A. Miller, Marjorie Perloff, Donna R. Vining, James A. Crowell, Linda L. Garland, Wade M. Chew, H-H. Sherry Chow

Resveratrol has been shown to exhibit cancer-preventive activities in preclinical studies. We conducted a clinical study to determine the effect of pharmacologic doses of resveratrol on drug- and carcinogen-metabolizing enzymes. Forty-two healthy vol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9643b6d3b865ab7c56026c9ba54c903b
https://europepmc.org/articles/PMC2933312/

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Quantification of a cytochrome P450 3A4 substrate, buspirone, in human plasma by liquid chromatography-tandem mass spectrometry

Autor: H-H. Sherry Chow, Min-Jian Xu, Wade M. Chew, Catherine A. Cordova

Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 844(2)

A sensitive HPLC-tandem mass spectrometry method was developed for determination of buspirone levels in human plasma. After solid phase extraction and reversed phase HPLC separation, detection of buspirone and the internal standard (prazosin) was per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e20c61c24142e62e3afaf41ba2f2b5c
https://pubmed.ncbi.nlm.nih.gov/16875888

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