Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wade L. Pearson"'
Autor:
Carol A. Vandenberg, Stephen Tucker, Paul A. Slesinger, Susumu Seino, Henry Sackin, Wade L. Pearson, Lawrence G. Palmer, Colin G. Nichols, Takashi Miki, Michel Lazdunski, Yoshihisa Kurachi, Yoshihiro Kubo, Andreas Karschin, Lily Y. Jan, Atsushi Inanobe, Hiroshi Hibino, David E. Clapham, John P. Adelman
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
The 2TM domain family of K channels are also known as the inward-rectifier K channel family. This family includes the strong inward-rectifier K channels (Kir2.x) that are constitutively active, the G-protein-activated inward-rectifier K channels (Kir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437282b9eb40f9fe5aee4ff9e747ca06
https://doi.org/10.2218/gtopdb/f74/2023.1
https://doi.org/10.2218/gtopdb/f74/2023.1
Autor:
Wade L. Pearson, Lawrence G. Palmer, Takashi Miki, John P. Adelman, Hiroshi Hibino, Carol A. Vandenberg, Paul A. Slesinger, Colin G. Nichols, David E. Clapham, Stephen J. Tucker, Susumu Seino, Michel Lazdunski, Yoshihisa Kurachi, Andreas Karschin, Lily Yeh Jan, Henry Sackin, Yoshihiro Kubo, Atsushi Inanobe
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
The 2TM domain family of K channels are also known as the inward-rectifier K channel family. This family includes the strong inward-rectifier K channels (Kir2.x) that are constitutively active, the G-protein-activated inward-rectifier K channels (Kir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fe218833754366593bc225e1faec67e
https://doi.org/10.2218/gtopdb/f74/2021.3
https://doi.org/10.2218/gtopdb/f74/2021.3
Autor:
Lily Yeh Jan, Yoshihiro Kubo, Colin G. Nichols, Takashi Miki, David E. Clapham, Henry Sackin, Atsushi Inanobe, Paul A. Slesinger, John P. Adelman, Andreas Karschin, Stephen J. Tucker, Yoshihisa Kurachi, Michel Lazdunski, Susumu Seino, Lawrence G. Palmer, Carol A. Vandenberg, Wade L. Pearson, Hiroshi Hibino
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE, vol 2019, iss 4
The 2TM domain family of K channels are also known as the inward-rectifier K channel family. This family includes the strong inward-rectifier K channels (Kir2.x) that are constitutively active, the G-protein-activated inward-rectifier K channels (Kir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c1ab58d2883712d98c7f198f525b30
https://doi.org/10.2218/gtopdb/f74/2019.4
https://doi.org/10.2218/gtopdb/f74/2019.4
Autor:
Darian A. Wigfall, Colin G. Nichols, Wade L. Pearson, Robert W. Mercer, Paul H. Schlesinger, Qun Sha, Lauren C. Burcea
Publikováno v:
American Journal of Physiology-Renal Physiology. 295:F91-F99
A mutation in the human FXYD2 polypeptide (Na-K-ATPase γ subunit) that changes a conserved transmembrane glycine to arginine is linked to dominant renal hypomagnesemia. Xenopus laevis oocytes injected with wild-type FXYD2 or the mutant G41R cRNAs ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adadcef1ea7cb3df63d844b4b1965eb
https://doi.org/10.1152/ajprenal.00519.2007
https://doi.org/10.1152/ajprenal.00519.2007
Publikováno v:
Journal of Membrane Biology. 213:187-193
Inward rectifier potassium (Kir) channels serve important functional and modulatory roles in a wide variety of cells. While the activity of several members of this channel family are tightly regulated by intracellular messengers such as adenosine tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11653507591ddac81cbb7abadb62dc3
https://doi.org/10.1007/s00232-006-0058-6
https://doi.org/10.1007/s00232-006-0058-6
Publikováno v:
The Journal of Physiology. 514:639-653
Since the cloning of the first inward rectifier K+ channel, ROMK1 (Kir1.1a: Ho et al. 1993), a large family of related Kir channel genes has been identified. These genes have been divided into seven subfamilies (to date) based on their predicted prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1a4b5cec27f30d993acb3bdc2e805c
https://doi.org/10.1111/j.1469-7793.1999.639ad.x
https://doi.org/10.1111/j.1469-7793.1999.639ad.x
Autor:
Wade L. Pearson, Colin G. Nichols
Publikováno v:
The Journal of General Physiology
Inward rectification induced by mono- and diaminoalkane application to inside-out membrane patches was studied in Kir2.1 (IRK1) channels expressed in Xenopus oocytes. Both monoamines and diamines block Kir2.1 channels, with potency increasing as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a31b223e8a9d506152e8bdf3f47848
https://doi.org/10.1085/jgp.112.3.351
https://doi.org/10.1085/jgp.112.3.351
Autor:
Michael Levin, Katia Carneiro, Joseph C. Koster, Wade L. Pearson, Sherry Aw, Colin G. Nichols, Nian-Qing Shi
Publikováno v:
Developmental biology. 346(1)
Consistent left-right asymmetry requires specific ion currents. We characterize a novel laterality determinant in Xenopus laevis: the ATP-sensitive K(+)-channel (K(ATP)). Expression of specific dominant-negative mutants of the Xenopus Kir6.1 pore sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5b4087a5a49298367a7fdac5d2a73b
https://pubmed.ncbi.nlm.nih.gov/20643119
https://pubmed.ncbi.nlm.nih.gov/20643119
Autor:
Yury V. Kucheryavykh, Colin G. Nichols, Wade L. Pearson, Harley T. Kurata, Misty J. Eaton, Serguei N. Skatchkov
Publikováno v:
Channels (Austin, Tex.). 1(3)
Inward rectifier K(+) (Kir) channels are expressed in multiple neuronal and glial cells. Recent studies have equated certain properties of exogenously expressed Kir4.1 channels with those of native K(+) currents in brain cells, as well as demonstrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103a78f7e6498b0a6307a1bd18406723
https://pubmed.ncbi.nlm.nih.gov/18690029
https://pubmed.ncbi.nlm.nih.gov/18690029
Autor:
Sergei M. Antonov, Mikhail Inyushin, Andreas Reichenbach, Yaroslav M. Shuba, Wade L. Pearson, Misty J. Eaton, Serguei N. Skatchkov, Luis A. Cubano, Yuriy V. Kucheryavykh, Colin G. Nichols, Harley T. Kurata, Rüdiger W. Veh
Publikováno v:
Glia
Although Kir4.1 channels are the major inwardly rectifying channels in glial cells and are widely accepted to support K(+)- and glutamate-uptake in the nervous system, the properties of Kir4.1 channels during vital changes of K(+) and polyamines rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2087eba27bdcf07c4b026781686eca23
https://pubmed.ncbi.nlm.nih.gov/18293411
https://pubmed.ncbi.nlm.nih.gov/18293411