Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wade L. Kadel"'
Publikováno v:
Journal of Toxicology and Environmental Health. 43:291-304
The objective of this investigation was to determine the distribution of cholinergic (acetyl-cholinesterase, AChE) and noncholinergic markers in slow-, fast-, and mixed-fiber containing muscles (soleus, SOL; extensor digitorum longus, EDL; and diaphr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6a48994aaad20bf9f677cd5666e19b
https://doi.org/10.1080/15287399409531922
https://doi.org/10.1080/15287399409531922
Publikováno v:
Journal of Toxicology and Environmental Health. 42:451-462
The objective of this investigation was to determine the changes in proteins, lipids, and lipoproteins in liver and serum of rats acutely intoxicated with carbofuran (1.5 mg/kg sc). Under the influence of carbofuran acute intoxication, analysis of gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408c6c276a3eb5016706d908172374a0
https://doi.org/10.1080/15287399409531895
https://doi.org/10.1080/15287399409531895
Publikováno v:
Drug Development Research. 28:153-160
Male Sprague-Dawley rats injected with a single acute dose of carbofuran (1.5 mg/kg, sc) developed chewing movements and fine tremors within 5–7 min. The signs of maximal severity with hypercholinergic preponderance including muscle fasciculations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58afc777a4abc85f951316b44b922cc7
https://doi.org/10.1002/ddr.430280205
https://doi.org/10.1002/ddr.430280205
Autor:
Wade L. Kadel, Ramesh C. Gupta
Publikováno v:
Drug Development Research. 24:343-353
Daily administration (i.p.) of aldicarb in male Sprague-Dawley rats at various dosage levels for 21 days revealed (1) 0.1 mg/kg, nontoxic dose; (2) 0.2 mg/kg, moderately toxic dose; and (3) 0.4 mg/kg, severely toxic dose, Inhibition of acetylcholines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::114219d1a3dcee3c8bc131f058a13e73
https://doi.org/10.1002/ddr.430240405
https://doi.org/10.1002/ddr.430240405
Autor:
Ramesh C. Gupta, Wade L. Kadel
Publikováno v:
Drug Development Research. 24:329-341
Administration of a single sublethal dose of aldicarb (0.4 mg/kg, i.p.) to male Sprague-Dawley rats produced the onset of hypercholinergic signs within 3–5 min. With increasing intensity the most severe signs, predominantly involving the peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b424e5b1317b43126ae8b2bca34d9bb0
https://doi.org/10.1002/ddr.430240404
https://doi.org/10.1002/ddr.430240404
Toxic interaction of tetraisopropylpyrophosphoramide and propoxur: Some insights into the mechanisms
Autor:
Ramesh C. Gupta, Wade L. Kadel
Publikováno v:
Archives of Environmental Contamination and Toxicology. 19:917-920
Propoxur with a non-toxic dose (5 mg/kg) administered intraperitoneally (ip) in tetraisopropylpyrophosphoramide (iso-OMPA, 1 mg/kg) pretreated rats subcutaneously, sc) produced severe intoxication of anticholinesterase nature. The observed severity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b437977eac84efaa73c9cf9cb96eb32f
https://doi.org/10.1007/bf01055061
https://doi.org/10.1007/bf01055061
Publikováno v:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 6(4)
Tobacco plants (Nicotiana spp.) are uncommon causes of poisoning in horses and mules. Most intoxications involving livestock result from the ingestion of limited quantities during gestation, causing teratogenic effects or congenital limb defects. A r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ccad6de347d9ae343df15702b5ffcef
https://pubmed.ncbi.nlm.nih.gov/7858037
https://pubmed.ncbi.nlm.nih.gov/7858037
Autor:
Pamela S. McLaughlin, M. M. Chengappa, Sherry C. Greer, Bruce G. McLaughlin, Roxanna L. Maddux, Shri N. Singh, Wade L. Kadel
Publikováno v:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 3(4)
A Pasteurella haemolytica-like organism was isolated from the intestines of 28 swine with clinical, gross, or microscopic evidence of enteritis. In 15 cases, other known enteric pathogens were also demonstrated, and in 13 cases, no other pathogens we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6392d668b1ec167834c634dbbaca9a6
https://pubmed.ncbi.nlm.nih.gov/1760465
https://pubmed.ncbi.nlm.nih.gov/1760465
Publikováno v:
Archives of environmental contamination and toxicology. 21(2)
Intoxication with an acute dose of carbofuran (1.5 mg/kg, sc) in male Sprague-Dawley rats evoked severe toxic manifestations characteristic of hypercholinergic preponderance with profound muscle fasciculations and convulsions during 30-60 min, lastin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf82dea90c00b4050b30e126136335ac
https://pubmed.ncbi.nlm.nih.gov/1958080
https://pubmed.ncbi.nlm.nih.gov/1958080
Autor:
Wade L. Kadel, Ramesh C. Gupta
Publikováno v:
Journal of Toxicology and Environmental Health. 26:447-457
Pretreatment of rats with the nonspecific esterase inhibitor iso-OMPA (1 mg/kg sc) 1 h prior to carbofuran (2,3-dihydro-2,2-dimethyl-7-benzofuranyl N-methylcarbamate, 0.5 mg/kg sc) administration potentiated carbofuran toxicity by more than threefold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e6c8ce882f731ea2029c5edf47c49a
https://doi.org/10.1080/15287398909531268
https://doi.org/10.1080/15287398909531268