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DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti‐DKK1 therapeutic DKN‐01.

Autor: Jarman, Edward J., Horcas‐Lopez, Marta, Waddell, Scott H., MacMaster, Stephanie, Gournopanos, Konstantinos, Soong, Daniel Y. H., Musialik, Kamila I., Tsokkou, Panagiota, Ng, Minn‐E, Cambridge, William A., Wilson, David H., Kagey, Michael H., Newman, Walter, Pollard, Jeffrey W., Boulter, Luke

Publikováno v: Liver International; Jan2023, Vol. 43 Issue 1, p208-220, 13p, 2 Charts, 4 Graphs

A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice

Autor: Ford, Matthew J., Yeyati, Patricia L., Mali, Girish R., Keighren, Margaret A., Waddell, Scott H., Mjoseng, Heidi K., Douglas, Adam T., Hall, Emma A., Sakaue-Sawano, Asako, Miyawaki, Atsushi, Meehan, Richard R., Boulter, Luke, Jackson, Ian J., Mill, Pleasantine, Mort, Richard L.

Publikováno v: Ford, M J, Yeyati, P, Mali, G, Keighren, M A, Waddell, S, Mjoseng, H K, Douglas, A T, Hall, E A, Sakaue-Sawano, A, Miyawaki, A, Meehan, R R, Boulter, L, Jackson, I J, Mill, P & Mort, R L 2018, ' A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice ', Developmental Cell, vol. 47, no. 4, pp. 509-523.e5 . https://doi.org/10.1016/j.devcel.2018.10.027
Ford, M J, Yeyati, P L, Mali, G R, Keighren, M A, Waddell, S H, Mjoseng, H K, Douglas, A T, Hall, E A, Sakaue-Sawano, A, Miyawaki, A, Meehan, R R, Boulter, L, Jackson, I J, Mill, P & Mort, R L 2018, ' A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice ', Developmental Cell, vol. 47, no. 4, E5, pp. 509-523 . https://doi.org/10.1016/j.devcel.2018.10.027
Developmental Cell

Summary The cilia and cell cycles are inextricably linked. Centrioles in the basal body of cilia nucleate the ciliary axoneme and sequester pericentriolar matrix (PCM) at the centrosome to organize the mitotic spindle. Cilia themselves respond to gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dbaa96089d1d75f1da6c917fa139efa3
https://www.pure.ed.ac.uk/ws/files/76966693/A_cell_cilia_cycle_biosensor_for_single_cell_kinetics_reveals_persistence_of_cilia_after_the_G1_S_transition_is_a_general_property_in_cells_and_mice.pdf