Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Wadah, Osman"'
Autor:
Wadah Osman, Shaza Shantier, Nazik Mohamed, Sahar Abdalla, Mona Mohamed, Yunsua Umar, Asmaa E. Sherif, Khaled M. Elamin, Ahmed Ashour
Publikováno v:
Pharmacia, Vol 71, Iss , Pp 1-10 (2024)
This study aimed to evaluate the xanthine oxidase (XO) inhibitory activities of seven compounds identified in the potent antioxidant ethyl acetate fraction of Ambrosia maritima L. using various computational tools. Physicochemical properties and dens
Externí odkaz:
https://doaj.org/article/4bed63bb594f466893323fcb01fc003e
Autor:
Abdulrahim A. Alzain, Fatima A. Elbadwi, Tagyedeen H. Shoaib, Asmaa E. Sherif, Wadah Osman, Ahmed Ashour, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Eun Joo Roh, Ahmed H. E. Hassan
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Pin1 is a pivotal player in interactions with a diverse array of phosphorylated proteins closely linked to critical processes such as carcinogenesis and tumor suppression. Its axial role in cancer initiation and progression, coupled with its overexpr
Externí odkaz:
https://doaj.org/article/32429af2ea054eaea28422d5062ac007
Autor:
Rua M. Mukhtar, Nihal Abdelmoniem, Hisham A. Elrufaie, Alaa Edris, Hiba Ghaboosh, Mohanad A. Mahgoub, Elrashied A. E. Garelnabi, Wadah Osman, Asmaa E. Sherif, Ahmed Ashour, Kholoud F. Ghazawi, Waad A. Samman, Aisha A. Alhaddad, Rawan Bafail, Sabrin R. M. Ibrahim, Gamal A. Mohamed, Abdulrahim A. Alzain
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Tropomyosin-receptor kinase A (TrkA) is the primary isoform among the tropomyosin-receptor kinases that have been associated with human cancer development, contributing to approximately 7.4% of all cancer cases. TrkA represents an attractive target f
Externí odkaz:
https://doaj.org/article/aa633d32a35748db8b9b28e5292dd174
Autor:
Bashir Abdrhman Bashir, Mohamed Hassan Mohamed, Mohamed A. Hussain, Wadah Osman, Ramzi A. Mothana, Sidgi Hasson
Publikováno v:
Medicina, Vol 59, Iss 10, p 1826 (2023)
Background and Objectives: HIV disease is recognized to cause inconsistencies in coagulation via various pathways during infection. Some studies have indicated that HIV-infected patients are prone to developing thrombocytopenia, thrombosis, or autoan
Externí odkaz:
https://doaj.org/article/fa0fdb7330bb41ef9d79c4cebf9a4bd6
Autor:
Tagyedeen H. Shoaib, Mohammed A. Almogaddam, Yusra Saleh Andijani, Samaher Ahmad Saib, Najwa Mahmoud Almaghrabi, Abdulaziz Fahad Elyas, Rahmah Yasin Azzouni, Ehda Ahmad Awad, Shaimaa G. A. Mohamed, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Hazem G. A. Hussein, Wadah Osman, Ahmed Ashour, Asmaa E. Sherif, Abdulrahim A. Alzain
Publikováno v:
Metabolites, Vol 13, Iss 10, p 1090 (2023)
Cyclin-dependent kinase 5 (CDK5) plays a crucial role in various biological processes, including immune response, insulin secretion regulation, apoptosis, DNA (deoxyribonucleic acid) damage response, epithelial−mesenchymal transition (EMT), cell mi
Externí odkaz:
https://doaj.org/article/b80dc87b53ad445faee3f2671c96d3be
Autor:
Tagyedeen H Shoaib, Walaa Ibraheem, Mohammed Abdelrahman, Wadah Osman, Asmaa E Sherif, Ahmed Ashour, Sabrin R M Ibrahim, Kholoud F Ghazawi, Samar F Miski, Sara A Almadani, Duaa Fahad ALsiyud, Gamal A Mohamed, Abdulrahim A Alzain
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0289887 (2023)
Triple-negative breast cancer (TNBC) is an aggressive malignancy that requires effective targeted drug therapy. In this study, we employed in silico methods to evaluate the efficacy of seven approved drugs against human ck2 alpha kinase, a significan
Externí odkaz:
https://doaj.org/article/99f11dd1bb524588ac12f2ab846f503d
Autor:
Abdulrahim A. Alzain, Rua M. Mukhtar, Nihal Abdelmoniem, Tagyedeen H. Shoaib, Wadah Osman, Marwa Alsulaimany, Ahmed K. B. Aljohani, Sara A. Almadani, Baiaan H. Alsaadi, Maryam M. Althubyani, Shaimaa G. A. Mohamed, Gamal A. Mohamed, Sabrin R. M. Ibrahim
Publikováno v:
Molecules, Vol 28, Iss 16, p 6003 (2023)
Oxidative stress plays a significant role in the development of cancer. Inhibiting the protein-protein interaction (PPI) between Keap1 and Nrf2 offers a promising strategy to activate the Nrf2 antioxidant pathway, which is normally suppressed by the
Externí odkaz:
https://doaj.org/article/65a8bc4f5bee40058f97d5d001b6c453
Autor:
Mohamed A. Hussain, Mohamed M. Hassan, Bashir Abdrhman Bashir, Tarig A. Gamar, Elmuaiz Gasmalbari, Ahmed Osman Mohamed, Wadah Osman, Asmaa E. Sherif, Abdelaziz Elgaml, Aisha A. Alhaddad, Kholoud F. Ghazawi, Samar F. Miski, Bayan E. Ainousah, Yusra Saleh Andijani, Sabrin R. M. Ibrahim, Gamal A. Mohamed, Ahmed Ashour
Publikováno v:
Pathogens, Vol 12, Iss 7, p 926 (2023)
The coronavirus has become the most interesting virus for scientists because of the recently emerging deadly SARS-CoV-2. This study aimed to understand the behavior of SARS-CoV-2 through the comparative genomic analysis with the closest one among the
Externí odkaz:
https://doaj.org/article/e76ac44ce2434f5c866f19b7d621a8d0
Autor:
Mohamed M. Hassan, Mohamed A. Hussain, Sababil S. Ali, Mohammed A. Mahdi, Nouh Saad Mohamed, Hanadi AbdElbagi, Osama Mohamed, Asmaa E. Sherif, Wadah Osman, Sabrin R. M. Ibrahim, Kholoud F. Ghazawi, Samar F. Miski, Gamal A. Mohamed, Ahmed Ashour
Publikováno v:
Medicina, Vol 59, Iss 6, p 1116 (2023)
Background: HLA-DRB1 is the most polymorphic gene in the human leukocyte antigen (HLA) class II, and exon 2 is critical because it encodes antigen-binding sites. This study aimed to detect functional or marker genetic variants of HLA-DRB1 exon 2 in r
Externí odkaz:
https://doaj.org/article/5f83becec8e8433ca916a51174b4a48c
Autor:
Mohamed A. Hussain, Malik Suliman Mohamed, Hisham N. Altayb, Ahmed Osman Mohamed, Ahmed Ashour, Wadah Osman, Asmaa E. Sherif, Kholoud F. Ghazawi, Samar F. Miski, Sabrin R. M. Ibrahim, Gamal A. Mohamed, Ikhlas A. Sindi, Ahmad A. Alshamrani, Abdelaziz Elgaml
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1432 (2023)
Pseudomonas aeruginosa (P. aeruginosa) is known to be associated with resistance to practically all known antibiotics. This is a cross-sectional, descriptive, laboratory-based analytical study in which 200 P. aeruginosa clinical isolates were involve
Externí odkaz:
https://doaj.org/article/1be84d60c1f041f486922d4d2934f2c2