Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis

Autor: Keiser, Patrick T., Zhang, Wenhan, Ricca, Michael, Wacquiez, Alan, Grimins, Autumn, Cencic, Regina, Patten, J.J., Shah, Pranav, Padilha, Elias, Connor, John H., Pelletier, Jerry, Lyons, Shawn M., Saeed, Mohsan, Brown, Lauren E., Porco, John A., Jr., Davey, Robert A.

Publikováno v: In Antiviral Research October 2024 230

Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1

Autor: Alan Wacquiez, Franck Coste, Emmanuel Kut, Virginie Gaudon, Sascha Trapp, Bertrand Castaing, Daniel Marc

Publikováno v: Viruses, Vol 12, Iss 9, p 947 (2020)

The non-structural protein NS1 of influenza A viruses is an RNA-binding protein of which its activities in the infected cell contribute to the success of the viral cycle, notably through interferon antagonism. We have previously shown that NS1 strong

Externí odkaz: https://doaj.org/article/3e53aa9508f14674a37d255a8f698c86

The metabolite succinate inhibits influenza virus replication through succinylation and nuclear retention of the viral nucleoprotein

Autor: Adeline Cezard, Antoine Guillon, Deborah Bréa-Diakite, Alan Wacquiez, Thomas Baranek, Jérôme Bourgeais, Frédéric Picou, Virginie Vasseur, Léa Meyer, Adrien Auvet, José M Carballido, Lydie Nadal Desbarats, Florent Dingli, Andrei Turtoi, Audrey Le Gouellec, Florence Fauvelle, Amélie Donchet, Thibaut Crépin, Pieter S. Hiemstra, Christophe Paget, Damarys Loew, Olivier Hérault, Nadia Naffakh, Ronan Le Goffic, Mustapha Si-Tahar

Publikováno v: Respiratory infections and bronchiectasis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77eb1d00189141bdc1516769156bf520
https://doi.org/10.1183/23120541.lsc-2022.119

Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1

Autor: Virginie Gaudon, Sascha Trapp, Emmanuel Kut, Franck Coste, Bertrand Castaing, Daniel Marc, A. Wacquiez

Publikováno v: Viruses
Volume 12
Issue 9
Viruses, MDPI, 2020, 12 (9), pp.947. ⟨10.3390/v12090947⟩
Viruses, MDPI, 2020, 12 (9), 25 p. ⟨10.3390/v12090947⟩
Viruses, Vol 12, Iss 947, p 947 (2020)
Viruses, 2020, 12 (9), 25 p. ⟨10.3390/v12090947⟩

The non-structural protein NS1 of influenza A viruses is an RNA-binding protein of which its activities in the infected cell contribute to the success of the viral cycle, notably through interferon antagonism. We have previously shown that NS1 strong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a52e71a2c362b8ed359221ca21ad53
https://pubmed.ncbi.nlm.nih.gov/32867106

Interaction de la protéine NS1 des virus influenza A avec l’ARN : mécanismes impliqués dans la reconnaissance spécifique

Autor: Marc, Daniel, Wacquiez, Alan, Goffinont, Stéphane, Nadan, Virginie, Coste, Franck, Kut, Emmanuel, Castaing, Bertrand

Publikováno v: 21. Journées Francophones de Virologie
21. Journées Francophones de Virologie, Mar 2019, Lyon, France. Virologie, 23, 2019

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2a75b54491ec35484b58a630b494edee
https://hal.inrae.fr/hal-02737761