Applicability of a computational design approach for synthetic riboswitches

Autor: Domin, Gesine, Findeiß, Sven, Wachsmuth, Manja, Will, Sebastian, Stadler, Peter F., Mörl, Mario

Publikováno v: Nucleic Acids Research, 2016 doi: 10.1093/nar/gkw1267

Riboswitches have gained attention as tools for synthetic biology, since they enable researchers to reprogram cells to sense and respond to exogenous molecules. In vitro evolutionary approaches produced numerous RNA aptamers that bind such small liga

Externí odkaz: https://ul.qucosa.de/id/qucosa%3A15259
https://ul.qucosa.de/api/qucosa%3A15259/attachment/ATT-0/

Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck

Autor: Li, Mingkun, Rothwell, Rebecca, Vermaat, Martijn, Wachsmuth, Manja, Schröder, Roland, Laros, Jeroen F J, Van Oven, Mannis, De Bakker, Paul I W, Bovenberg, Jasper A., Van Duijn, Cornelia M., Van Ommen, Gert Jan B, Slagboom, P. Eline, Swertz, Morris A., Wijmenga, Cisca, Kayser, Manfred, Boomsma, Dorret I., Zöllner, Sebastian, De Knijff, Peter, Stoneking, Mark, De Craen, Anton J M, Beekman, Marian, Hofman, Albert, Willemsen, Gonneke, Wolffenbuttel, Bruce, Platteel, Mathieu, Du, Yuanping, Chen, Ruoyan, Cao, Hongzhi, Cao, Rui, Sun, Yushen, Cao, Jeremy Sujie, Van Dijk, Freerk, Neerincx, Pieter B T, Deelen, Patrick, Dijkstra, Martijn, Byelas, George, Kanterakis, Alexandros, Bot, Jan, Ye, Kai, Lameijer, Eric Wubbo, Den Dunnen, Johan T., Karssen, Lennart C., Van Leeuwen, Elisa M., Amin, Najaf, Koval, Vyacheslav, Rivadeneira, Fernando, Estrada, Karol, Hehir-Kwa, Jayne Y., De Ligt, Joep, Abdellaoui, Abdel, Hottenga, Jouke Jan, Kattenberg, V. Mathijs, Van Enckevort, David, Mei, Hailiang, Santcroos, Mark, Van Schaik, Barbera D C, Handsaker, Robert E., McCarroll, Steven A., Eichler, Evan E., Ko, Arthur, Sudmant, Peter, Francioli, Laurent C., Kloosterman, Wigard P., Nijman, Isaac J., Guryev, Victor

Publikováno v: Li, M, Rothwell, R, Vermaat, M, Wachsmuth, M, Schröder, R, Laros, J F J, van Oven, M, Bakker, P I W, Bovenberg, J A, van Duijn, C M, van Ommen, G J B, Slagboom, P E, Swertz, M A, Wijmenga, C, Kayser, M, Boomsma, D I, Zöllner, S, de Knijff, P & Stoneking, M 2016, ' Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck ', Genome Research, vol. 26, no. 4, pp. 417-426 . https://doi.org/10.1101/gr.203216.115
Genome Research, 26(4), 417-426
Genome Research, 26(4), 417-426. Cold Spring Harbor Laboratory Press
Genome Research, 26(4), 417-426. COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Genome Research, 26(4), 417. Cold Spring Harbor Laboratory Press

Although previous studies have documented a bottleneck in the transmission of mtDNA genomes from mothers to offspring, several aspects remain unclear, including the size and nature of the bottleneck. Here, we analyze the dynamics of mtDNA heteroplasm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34488ab6e37c92f6acc40434706a049a
https://doi.org/10.1101/gr.203216.115

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome.

Autor: Hübner, Alexander¹ alexander_huebner@eva.mpg.de, Wachsmuth, Manja¹, Schröder, Roland¹, Li, Mingkun², Eis-Hübinger, Anna Maria³, Madea, Burkhard⁴, Stoneking, Mark¹ stonekg@eva.mpg.de

Publikováno v: Scientific Reports. 8/2/2019, Vol. 9 Issue 1, pN.PAG-N.PAG. 1p.

Vanilla Table.

Autor: Harmer, Janet

Publikováno v: Caterer (2055-7817). 04/03/2015, p49-49. 1/2p.