Výsledky vyhledávání - "Wachirun Terakosolphan"

A novel method for studying airway hyperresponsiveness in allergic guinea pigs in vivo using the PreciseInhale system for delivery of dry powder aerosols

Autor: Clive P. Page, Wachirun Terakosolphan, Ben Forbes, Anne J. Lexmond, S. Keir

Publikováno v: Drug delivery and translational research, 8(3), 760-769. SPRINGER HEIDELBERG
Drug Delivery and Translational Research

Inhaled adenosine receptor agonists induce bronchoconstriction and inflammation in asthma and are used as bronchial challenge agents for the diagnosis of asthma and in respiratory drug development. Recently developed dry powder aerosols of adenosine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1596379dfe4ab0599c599623cceb856e
https://doi.org/10.1007/s13346-018-0490-z

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In vitro Fourier transform infrared spectroscopic study of the effect of glycerol on the uptake of beclomethasone dipropionate in living respiratory cells

Autor: K. L. Andrew Chan, Anchisa Poonprasartporn, Wachirun Terakosolphan, Richard D. Harvey, Ben Forbes, Ali Altharawi

Publikováno v: International Journal of Pharmaceutics. 609:121118

The quantification of drug in living cells is of increasing interest in pharmaceutical research because of its importance in understanding drug efficacy and toxicity. Label-free in situ measurement methods are advantageous for their ability to obtain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25800d54635388492d913ef56c3bf61c
https://doi.org/10.1016/j.ijpharm.2021.121118

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Glycerol solvates DPPC headgroups and localises in the interfacial regions of model pulmonary interfaces altering bilayer structure

Autor: Wachirun Terakosolphan, Jemma L. Trick, Ben Forbes, Sarah E. Rogers, Christian D. Lorenz, Olimpia Lamberti, Paul G. Royall, Richard D. Harvey

Publikováno v: Terakosolphan, W, Trick, J L, Royall, P G, Rogers, S E, Lamberti, O, Lorenz, C D, Forbes, B & Harvey, R D 2018, ' Glycerol solvates DPPC headgroups and localises in the interfacial regions of model pulmonary interfaces altering bilayer structure ', LANGMUIR . https://doi.org/10.1021/acs.langmuir.8b00866

The inclusion of glycerol in formulations for pulmonary drug delivery may affect the bioavailability of inhaled steroids by retarding their transport across the lung epithelium. The aim of this study was to evaluate whether the molecular interactions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2071f65a3d0ba7ddf481c26332da64f2
https://kclpure.kcl.ac.uk/ws/files/97287251/Glycerol_solvates_DPPC_headgroups_TERAKOSOLPHAN_Firstonline8May2018_GREEN_AAMa.pdf

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A Biocompatible Synthetic Lung Fluid Based on Human Respiratory Tract Lining Fluid Composition

Autor: Mireille Hassoun, Astrid Novicky, Jonny Eriksson, Elif Melis Bicer, Dirk Valkenborg, Inge Nelissen, Abhinav Kumar, Paul G. Royall, Ian Mudway, Richard D. Harvey, Kalliopi-Kelli A. Vandera, Wachirun Terakosolphan, Dave Hassall, Katarina Edwards, Ben Forbes

Publikováno v: Pharmaceutical research
Pharmaceutical Research
Kumar, A, Terakosolphan, W, Hassoun, M, Vandera, K-K, Novicky, A, Harvey, R, Royall, P G, Bicer, E M, Eriksson, J, Edwards, K, Valkenborg, D, Nelissen, I, Hassall, D, Mudway, I & Forbes, B 2017, ' A Biocompatible Synthetic Lung Fluid Based on Human Respiratory Tract Lining Fluid Composition ', Pharmaceutical Research, pp. 1-12 . https://doi.org/10.1007/s11095-017-2169-4

To characterise a biorelevant simulated lung fluid (SLF) based on the composition of human respiratory tract lining fluid. SLF was compared to other media which have been utilized as lung fluid simulants in terms of fluid structure, biocompatibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b252001badf00ffd935667aea61326
http://hdl.handle.net/1942/26351

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Simulations of Glycerol and its Effect on the Phase and Behaviour of DPPC Monolayers

Autor: Jemma L. Trick, Wachirun Terakosolphan, Christian D. Lorenz, Ben Forbes

Publikováno v: Biophysical Journal. 112:73a

Lung Surfactant (LS), a monolayer coating the alveolar surface undergoes changes during breathing. Glycerol, a known cryo-protectant is known to induce folding in LS, stiffening in model LS monolayers, modulate area per lipid, and the transition temp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc9fa50cfc32ce8c44eb653b81ff18da
https://doi.org/10.1016/j.bpj.2016.11.441

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