Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Wacharee Harnying"'
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Akademický článek
Salicylic diamines selectively eliminate residual undifferentiated cells from pluripotent stem cell-derived cardiomyocyte preparations
Autor: Karsten Burkert, Hadiseh Taheri, Sarkawt Hamad, Matteo Oliverio, Gabriel Peinkofer, Jan-Wilhelm Kornfeld, Wacharee Harnying, Kurt Pfannkuche, Jürgen Hescheler, Albrecht Berkessel, Tomo Šarić
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Clinical translation of pluripotent stem cell (PSC) derivatives is hindered by the tumorigenic risk from residual undifferentiated cells. Here, we identified salicylic diamines as potent agents exhibiting toxicity to murine and human PSCs bu
Externí odkaz: https://doaj.org/article/c42a4101eb364861aadfd22f6d533faa
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3
Salicylic diamines selectively eliminate residual undifferentiated cells from pluripotent stem cell-derived cardiomyocyte preparations
Autor: Kurt Pfannkuche, Jürgen Hescheler, Albrecht Berkessel, Jan-Wilhelm Kornfeld, Sarkawt Hamad, Tomo Saric, Hadiseh Taheri, Wacharee Harnying, Karsten Burkert, Gabriel Peinkofer, Matteo Oliverio
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports
Clinical translation of pluripotent stem cell (PSC) derivatives is hindered by the tumorigenic risk from residual undifferentiated cells. Here, we identified salicylic diamines as potent agents exhibiting toxicity to murine and human PSCs but not to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a909aee23e0b3cbda88833151308e6
https://doaj.org/article/c42a4101eb364861aadfd22f6d533faa
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4
Enantiospecific Synthesis of Nepetalactones by One-Step Oxidative NHC Catalysis
Autor: Albrecht Berkessel, Jörg-M. Neudörfl, Wacharee Harnying
Publikováno v: Organic Letters. 22:386-390
An efficient oxidative NHC-catalyzed one-step transformation of (S)- or (R)-8-oxocitronellal to nepetalactone (NL) in enantio- and diastereomerically pure form has been developed. Several new and “easy to make” N-Mes- or N-Dipp-substituted 1,2,4-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b0db62866aa5b8426c3c4f264a912a
https://doi.org/10.1021/acs.orglett.9b04034
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5
N-Heterocyclic Carbene/Carboxylic Acid Co-Catalysis Enables Oxidative Esterification of Demanding Aldehydes/Enals, at Low Catalyst Loading
Autor: Wacharee Harnying, Panyapon Sudkaow, Animesh Biswas, Albrecht Berkessel
Publikováno v: Angewandte Chemie (International Ed. in English)
We report the discovery that simple carboxylic acids, such as benzoic acid, boost the activity of N‐heterocyclic carbene (NHC) catalysts in the oxidative esterification of aldehydes. A simple and efficient protocol for the transformation of a wide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b78571d36e02f845e0f62f690f23e7
https://pubmed.ncbi.nlm.nih.gov/34010504
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6
Catalytic Prins Reaction Effected by Molecular Iodine in the Presence­ of Bis(trifluoromethanesulfonyl)imide Salts
Autor: Wacharee Harnying, Jörg-M. Neudörfl, Albrecht Berkessel
Publikováno v: Synthesis. 49:269-274
The Prins reaction is an efficient method for the direct generation of 1,3-dioxanes from alkenes and aldehydes. As first published in 2008, this process can be effected by stoichiometric amounts of molecular iodine. We herein report a catalytic proto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6541231c451b3b3f3847b15adb92326
https://doi.org/10.1055/s-0036-1588367
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9
1,4-Bis-Dipp/Mes-1,2,4-Triazolylidenes: Carbene Catalysts That Efficiently Overcome Steric Hindrance in the Redox Esterification of α- and β-Substituted α,β-Enals
Autor: Nils Schlörer, Albrecht Berkessel, Wacharee Harnying, Darius Kootz, Veera Reddy Yatham, Jörg-Martin Neudörfl
Publikováno v: Journal of the American Chemical Society. 138(8)
As reported by Scheidt and Bode in 2005, sterically nonencumbered α,β-enals are readily converted to saturated esters in the presence of alcohols and N-heterocyclic carbene catalysts, e.g., benzimidazolylidenes or triazolylidenes. However, substitu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d322c0861b81aafac4e92762a7f8f10
https://pubmed.ncbi.nlm.nih.gov/26797403
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10
Large-Scale Synthesis of Singh’s Catalyst in a One-Pot Procedure Starting from Proline
Autor: Nongnaphat Duangdee, Harald Gröger, Albrecht Berkessel, Wacharee Harnying, Jörg-M. Neudörfl
Publikováno v: Organic Process Research & Development. 16:123-128
A practical one-pot procedure for the preparation of Singh's catalyst from either L-/D-proline or Boc-proline is described. The coupling partner, a chiral amino alcohol, can be prepared and used directly without purification from the corresponding am
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391d59512fd05ab4b876ab450a290351
https://doi.org/10.1021/op200283q
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