Zobrazeno 1 - 10
of 812
pro vyhledávání: '"WYLIE VALE"'
The primary response to a stressful event is activation of the hypothalamic–pituitary–adrenal axis. The stress response results in the synthesis and release of corticotropin-releasing hormone (CRH) from the hypothalamus, followed by an increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d208c0b028945c59213a1e3f2564a935
https://doi.org/10.1016/b978-0-12-809324-5.03380-0
https://doi.org/10.1016/b978-0-12-809324-5.03380-0
Autor:
Wylie Vale, Eran Gershon
Publikováno v:
Obesity. 22:380-389
Objective Ghrelin is known to regulate appetite control and cellular metabolism. The corticotropin-releasing factor (CRF) family is also known to regulate energy balance. In this study, the links between ghrelin and the CRF family in C2C12 cells, a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3853e5cc706e0d71d39fde5aeb510135
https://doi.org/10.1002/oby.20535
https://doi.org/10.1002/oby.20535
Autor:
Mark O. Huising, Danhong Lu, Hans E. Hohmeier, Paul B. Rosenberg, Hengtao Zhang, Mette V. Jensen, Christopher B. Newgard, Wylie Vale, Jonathan M. Haldeman
Publikováno v:
Journal of Biological Chemistry. 288:23128-23140
Recent studies have shown that the pyruvate-isocitrate cycling pathway, involving the mitochondrial citrate/isocitrate carrier and the cytosolic NADP-dependent isocitrate dehydrogenase (ICDc), is involved in control of glucose-stimulated insulin secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb440cb7cc326c0f5c2ed00ba13a69c
https://doi.org/10.1074/jbc.m113.491654
https://doi.org/10.1074/jbc.m113.491654
Autor:
Wolfgang H. Fischer, Jean Rivier, Wylie Vale, Marilyn H. Perrin, Cynthia J. Donaldson, Joan Vaughan, Paul E. Sawchenko
Publikováno v:
Endocrinology. 154:1553-1564
Mouse (m) and human (h) urocortin 2 (Ucn 2) were identified by molecular cloning strategies and the primary sequence of their mature forms postulated by analogy to closely related members of the corticotropin-releasing factor (CRF) neuropeptide famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c114aaaae6a676ee786ea25f2fd2310
https://doi.org/10.1210/en.2012-2011
https://doi.org/10.1210/en.2012-2011
Autor:
Michael A. Staup, Kenner C. Rice, Robert A. Rissman, Paul E. Sawchenko, Wylie Vale, Nicholas J. Justice, Allyson Roe Lee
Publikováno v:
Proceedings of the National Academy of Sciences. 109:6277-6282
Exposure and/or sensitivity to stress have been implicated as conferring risk for development of Alzheimer's disease (AD). Although the basis for such a link remains unclear, we previously reported differential involvement of corticotropin-releasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9e3160c2574290fa020ad03553d79e
https://doi.org/10.1073/pnas.1203140109
https://doi.org/10.1073/pnas.1203140109
Autor:
Wylie Vale, Peter C. Gray
Publikováno v:
FEBS Letters. 586:1836-1845
Cripto is a small, GPI-anchored signaling protein that regulates cellular survival, proliferation, differentiation and migration during normal developmental processes and tumorigenesis. Cripto functions as an obligatory co-receptor for the TGF-β lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fc9bcc5bbfc03a15459f2199765519
https://doi.org/10.1016/j.febslet.2012.01.051
https://doi.org/10.1016/j.febslet.2012.01.051
Autor:
Valentina Sabino, Attila Szücs, Yu Zhao, Wylie Vale, Pietro Cottone, Jean Rivier, George F. Koob, Eric P. Zorrilla, Eva M. Fekete
Publikováno v:
British Journal of Pharmacology. 164:1959-1975
BACKGROUND AND PURPOSE Infusion of corticotropin-releasing factor (CRF)/urocortin (Ucn) family peptides suppresses feeding in mice. We examined whether rats show peripheral CRF/Ucn-induced anorexia and determined its behavioural and pharmacological b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c8e22da2e8c79bb5f3e1e43604a206b
https://doi.org/10.1111/j.1476-5381.2011.01512.x
https://doi.org/10.1111/j.1476-5381.2011.01512.x
Autor:
Enrrico Bloise, Fernando M. Reis, Peter C. Gray, Mario Castellucci, Md. Soriful Islam, Felice Petraglia, Wylie Vale, Pasquapina Ciarmela
Publikováno v:
Human Reproduction Update. 17:772-790
Background Growth factors are proteins secreted by a number of cell types that are capable of modulating cellular growth, proliferation and cellular differentiation. It is well accepted that uterine cellular events such as proliferation and different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9a39c6553aa6aeca7d90ab7249eeec
https://doi.org/10.1093/humupd/dmr031
https://doi.org/10.1093/humupd/dmr031
Publikováno v:
Angewandte Chemie International Edition. 50:8077-8081
Although G-protein coupled receptors (GPCRs) are the molecular target of almost half of today's pharmaceuticals, little is known about the molecular basis of the specific interaction with their ligands, due to the difficulty of obtaining spectroscopi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f369b2fbd89184cf849b3ccc80f3cab
https://doi.org/10.1002/anie.201102646
https://doi.org/10.1002/anie.201102646
Autor:
Wylie Vale, Louise M. Bilezikjian
Publikováno v:
The Open Neuroendocrinology Journal. 4:90-101
The pituitary gland plays a prominent role in the control of many physiological processes. This control is achieved through the actions and interactions of hormones and growth factors that are produced and secreted by the endocrine cell types and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2254778823897fadf3cbf47d31b51d
https://doi.org/10.2174/1876528901104010090
https://doi.org/10.2174/1876528901104010090