Zobrazeno 1 - 10
of 389
pro vyhledávání: '"WWTR1"'
Autor:
Xiaobo Wang, Mary P. Moore, Hongxue Shi, Yoshinari Miyata, Sara K. Donnelly, Daniel R. Radiloff, Ira Tabas
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101165- (2023)
Nonalcoholic steatohepatitis (NASH) is emerging as the most common cause of liver disease. Although many studies in mouse NASH models have suggested therapies, translation to humans is poor, with no approved drugs for NASH. One explanation may lie in
Externí odkaz:
https://doaj.org/article/05784e6569ad435ca672dd324341be8b
Publikováno v:
Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-5 (2022)
Abstract Background Wisconsin syndrome is a congenital anomaly caused by a 3q interstitial deletion. It is associated with characteristic facies and developmental delays. Only 33 cases with a deletion estimated to be in the associated region 3q25 hav
Externí odkaz:
https://doaj.org/article/ce2944a4c956480298f329c9ac9ae1ad
Autor:
Silvia Sberna, Alejandro Lopez-Hernandez, Chiara Biancotto, Luca Motta, Adrian Andronache, Lisette G. G. C. Verhoef, Marieta Caganova, Stefano Campaner
Publikováno v:
Cells, Vol 12, Iss 20, p 2431 (2023)
TAZ (WWTR1) is a transcriptional co-activator regulated by Hippo signaling, mechano-transduction, and G-protein couple receptors. Once activated, TAZ and its paralogue, YAP1, regulate gene expression programs promoting cell proliferation, survival, a
Externí odkaz:
https://doaj.org/article/af2426fbd3f3490c92e31ba4ae403efd
Akademický článek
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Publikováno v:
Clinical Case Reports, Vol 9, Iss 3, Pp 1494-1499 (2021)
Abstract Pseudomyogenic hemangioendothelioma rarely arises in bone. WWTR1‐FOSB fusion gene is rarely reported in PMHE of bone. Currently, fusion genes can be used as diagnostic markers in PMHE; however, their prognostic and therapeutic significance
Externí odkaz:
https://doaj.org/article/85603e0e4c1e48fc83c0415a9dc067fd
Akademický článek
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Autor:
Jing Wei, Lincui Wang, Jun Zhu, Aiqin Sun, Guanzhen Yu, Miao Chen, Pan Huang, Hanqing Liu, Genbao Shao, Wannian Yang, Qiong Lin
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Gastric cardia adenocarcinoma (GCA) is an aggressive subtype of gastric cancer with a high metastatic rate. However, the metastatic biomarker of GCA has not been established. Methods To search for the biomarker for GCA metastasis,
Externí odkaz:
https://doaj.org/article/e78cafdfeca348eca25523b7a426f821
Autor:
Anita K. Luu, Courtney R. Schott, Robert Jones, Andrew C. Poon, Brandon Golding, Roa’a Hamed, Benjamin Deheshi, Anthony Mutsaers, Geoffrey A. Wood, Alicia M. Viloria-Petit
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-22 (2018)
Abstract Background Osteosarcoma (OSA) is the most common bone cancer in canines. Both transforming growth factor beta (TGFβ) and Hippo pathway mediators have important roles in bone development, stemness, and cancer progression. The role of Hippo s
Externí odkaz:
https://doaj.org/article/ddcbebe4d6584af29ec56864122313b1
Akademický článek
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Autor:
Anh Phuong Luu, Zhenlan Yao, Sangeetha Ramachandran, Stephanie A. Azzopardi, Linde A. Miles, William M. Schneider, H.-Heinrich Hoffmann, Leonia Bozzacco, Gustavo Garcia, Danyang Gong, Robert Damoiseaux, Hengli Tang, Kouki Morizono, Charles M. Rudin, Ren Sun, Vaithilingaraja Arumugaswami, John T. Poirier, Margaret R. MacDonald, Charles M. Rice, Melody M. H. Li
Publikováno v:
Viruses, Vol 13, Iss 11, p 2113 (2021)
Zika virus (ZIKV) is a re-emerging flavivirus that has caused large-scale epidemics. Infection during pregnancy can lead to neurologic developmental abnormalities in children. There is no approved vaccine or therapy for ZIKV. To uncover cellular path
Externí odkaz:
https://doaj.org/article/2f3d203580654a47b1222b3bf06f5e6f