Zobrazeno 1 - 10
of 45
pro vyhledávání: '"WTCCC"'
Autor:
Adriana Huertas-Vazquez, Christopher P Nelson, Xiuqing Guo, Kyndaron Reinier, Audrey Uy-Evanado, Carmen Teodorescu, Jo Ayala, Katherine Jerger, Harpriya Chugh, WTCCC, Peter S Braund, Panos Deloukas, Alistair S Hall, Anthony J Balmforth, Michelle Jones, Kent D Taylor, Sara L Pulit, Christopher Newton-Cheh, Karen Gunson, Jonathan Jui, Jerome I Rotter, Christine M Albert, Nilesh J Samani, Sumeet S Chugh
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59905 (2013)
Recent genome-wide association studies (GWAS) have identified novel loci associated with sudden cardiac death (SCD). Despite this progress, identified DNA variants account for a relatively small portion of overall SCD risk, suggesting that additional
Externí odkaz:
https://doaj.org/article/21589e96400f420a8dc1b3e9803ec8ce
Autor:
Melanie Kolz, Toby Johnson, Serena Sanna, Alexander Teumer, Veronique Vitart, Markus Perola, Massimo Mangino, Eva Albrecht, Chris Wallace, Martin Farrall, Asa Johansson, Dale R Nyholt, Yurii Aulchenko, Jacques S Beckmann, Sven Bergmann, Murielle Bochud, Morris Brown, Harry Campbell, EUROSPAN Consortium, John Connell, Anna Dominiczak, Georg Homuth, Claudia Lamina, Mark I McCarthy, ENGAGE Consortium, Thomas Meitinger, Vincent Mooser, Patricia Munroe, Matthias Nauck, John Peden, Holger Prokisch, Perttu Salo, Veikko Salomaa, Nilesh J Samani, David Schlessinger, Manuela Uda, Uwe Völker, Gérard Waeber, Dawn Waterworth, Rui Wang-Sattler, Alan F Wright, Jerzy Adamski, John B Whitfield, Ulf Gyllensten, James F Wilson, Igor Rudan, Peter Pramstaller, Hugh Watkins, PROCARDIS Consortium, Angela Doering, H-Erich Wichmann, KORA Study, Tim D Spector, Leena Peltonen, Henry Völzke, Ramaiah Nagaraja, Peter Vollenweider, Mark Caulfield, WTCCC, Thomas Illig, Christian Gieger
Publikováno v:
PLoS Genetics, Vol 5, Iss 6, p e1000504 (2009)
Elevated serum uric acid levels cause gout and are a risk factor for cardiovascular disease and diabetes. To investigate the polygenetic basis of serum uric acid levels, we conducted a meta-analysis of genome-wide association scans from 14 studies to
Externí odkaz:
https://doaj.org/article/ff4cc331981e449292132db7bb00d13e
Autor:
The Wellcome Trust Case Control Consortium (WTCCC), Zeggini, Eleftheria, Weedon, Michael N., Lindgren, Cecilia M., Frayling, Timothy M., Elliott, Katherine S., Lango, Hana, Timpson, Nicholas J., Perry, John R. B., Rayner, Nigel W., Freathy, Rachel M., Barrett, Jeffrey C., Shields, Beverley, Morris, Andrew P., Ellard, Sian, Groves, Christopher J., Harries, Lorna W., Marchini, Jonathan L., Owen, Katharine R., Knight, Beatrice, Cardon, Lon R., Walker, Mark, Hitman, Graham A., Morris, Andrew D., Doney, Alex S. F., McCarthy, Mark I., Hattersley, Andrew T.
Publikováno v:
Science, 2007 Jun 01. 316(5829), 1336-1341.
Externí odkaz:
https://www.jstor.org/stable/20036395
Autor:
Renato Umeton, Sandra D'Alfonso, Paola de Candia, Antonio Uccelli, Cinthia Farina, Maria Chiara Buscarinu, Giuseppe Matarese, Gianmarco Bellucci, Roberta Magliozzi, Virginia Rinaldi, Silvia Romano, Imsgc, Arianna Fornasiero, Michela Ferraldeschi, Daniela F. Angelini, Pankaj Trivedi, Diego Centonze, Gisella Guerrera, Rosella Mechelli, Richard Reynolds, Rachele Bigi, Eleni Anastasiadou, Luca Battistini, Sundararajan Srinivasan, Marco Salvetti, Giovanni Ristori, Raffaella Pizzolato Umeton, Wtccc, Pierluigi Mauri, Dario Di Silvestre
SUMMARYWe exploited genetic information to assess non-genetic influences in autoimmunity. We isolated gene modules whose products physically interact with environmental exposures related to autoimmunity, and analyzed their nominal statistical evidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03c7498d91cacea31e3e8d3c025aa7d6
https://doi.org/10.1101/2021.06.06.447253
https://doi.org/10.1101/2021.06.06.447253
Autor:
Rosella Mechelli, Imsgc, Arianna Fornasiero, Cinthia Farina, Diego Centonze, Renato Umeton, Giovanni Ristori, Michela Ferraldeschi, Marco Salvetti, Wtccc, Sundararajan Srinivasan
SUMMARYWe exploited genetic information to assess the role of non-genetic factors in multifactorial diseases. To this aim we isolated candidate “interactomes” (i.e. groups of genes whose products are known to physically interact with environmenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc50ba5a9b18c3f577343c94e6603ef
https://doi.org/10.1101/624049
https://doi.org/10.1101/624049
Autor:
Miina Ollikainen, Johannes Hebebrand, Anke Hinney, André Scherag, Miriam Kesselmeier, Wtccc, Cynthia M. Bulik, Eleftheria Zeggini, Khadeeja Ismail, Anna-Lena Volckmar, Gcan, Carolin Pütter, Anna Keski-Rahkonen, Yasmina Silén, Thomas Illig, Hansjörg Baurecht, Harald Grallert, David A. Collier
Publikováno v:
ResearcherID
Europe PubMed Central
Europe PubMed Central
Objectives: Patients with anorexia nervosa (AN) are ideally suited to identify differentially methylated genes in response to starvation. Methods: We examined high-throughput DNA methylation derived from whole blood of 47 females with AN, 47 lean fem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecd4d345e034c3b1be1cb199e32e716
https://www.ncbi.nlm.nih.gov/pubmed/27367046
https://www.ncbi.nlm.nih.gov/pubmed/27367046
Autor:
Zeggini, E, Weedon, M, Lindgren, C, Frayling, T, Elliott, K, Lango, H, Timpson, N, Perry, J, Rayner, N, Freathy, R, Barrett, J, Groves, C, Morris, A, Hattersley, A, McCarthy, M, Consort, U, WTCCC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::755de1b4fa57550a4cab7ea68db44494
https://ora.ox.ac.uk/objects/uuid:e52eab56-6752-41d9-b7fc-60493e62a2c4
https://ora.ox.ac.uk/objects/uuid:e52eab56-6752-41d9-b7fc-60493e62a2c4
Autor:
Timpson, N, Zeggini, E, Weedon, M, Lingdren, C, Frayling, T, Elliott, K, Lango, H, Perry, J, Rayner, N, Freathy, R, Barret, J, Groves, C, Morris, A, Hattersley, A, McCarthy, M, Consort, U, WTCCC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::7b7bf6545f163fb553a2dc1ecdba7146
https://ora.ox.ac.uk/objects/uuid:93526ada-27e2-4eda-b9d3-2cf7fe79b929
https://ora.ox.ac.uk/objects/uuid:93526ada-27e2-4eda-b9d3-2cf7fe79b929
Autor:
Nag, A., Venturini, C., Small, K.S., Young, T. L., Viswanathan, A.C., Mackey, D.A., Hysi, P.G., Hammond, C., Aung, T., Cheng, C.-Y., Fleck, B.W., Gibson, J., Hewitt, A.W., Hofman, A., Hohn, R., Jonas, J.B., Khor, C.-C., Klaver, C.C., Lemij, H.G., Liao, J., Lotery, A.J., Lu, Y., Macgregor, S., Mitchell, P., Ramdas, W.D., Springelkamp, H., Tai, E.-S., Teo, Y.-Y., Uitterlinden, A.G., van Duijn, C.M., van Koolwijk, L.M., Vingerling, J.R., Vitart, V., Vithana, E., Wang, J.J., Williams, K.M., Wojciechowski, R., Wong, T.-Y., WTCCC, None, Xu, L., Yonova-Doing, E., Tanja, Z.
Glaucoma is a major cause of blindness in the world. To date, common genetic variants associated with glaucoma only explain a small proportion of its heritability. We performed a genome-wide association study of intra-ocular pressure (IOP), an underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______348::73183001808b67ce8e7c8df1e1bd1c2a
https://eprints.soton.ac.uk/368924/
https://eprints.soton.ac.uk/368924/
Autor:
I Quintela, I Deary, O Wolstein, Omar M. E. Albagha, M Sims, Kaare M. Gautvik, Lizbeth Herrera, Wtccc, Ole Kristoffer Olstad, Stuart H. Ralston, C Fernandez, G Davies, Ling Oei, Janja Marc, M C Medina-Gomez, Natalia Garcia-Giralt, S Kaptoge, Pino J del, S Mencej-Bedrac, R Gonzalez-Sarmiento, Jonathan Reeve, J Starr, Matthew A. Brown, R Prince, Carolina Sañudo, José M. Olmos, José A. Riancho, D Kabir, Karol Estrada, Roberto Elosua, M Melbye, L Stenkjaer, Fernando Rivadeneira, A Carracedo, Nerea Alonso, G Lucas, L Bjerre, Sjur Reppe, Bente L. Langdahl, Xavier Nogués, J Lewis, André G. Uitterlinden, Emma L. Duncan, John A. Eisman, B Feenstra
Publikováno v:
Bone Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71768573b16d77b2b489ba18223d4539
https://doi.org/10.1530/boneabs.01.oc3.5
https://doi.org/10.1530/boneabs.01.oc3.5