Wilms’ tumor 1-associating protein complex regulates alternative splicing and polyadenylation at potential G-quadruplex-forming splice site sequences

Autor: Takao Hamakubo, Takeshi Kawamura, Keiko Horiuchi

Publikováno v: The Journal of Biological Chemistry

Wilms’ tumor 1-associating protein (WTAP) is a core component of the N6-methyladenosine (m6A)-methyltransferase complex, along with VIRMA, CBLL1, ZC3H13 (KIAA0853), RBM15/15B, and METTL3/14, which generate m6A, a key RNA modification that affects v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75a0e73b4f04a13642d9f9cd4d5690a
http://europepmc.org/articles/PMC8605363

IGF2BP3 is an essential N ⁶ -methyladenosine biotarget for suppressing ferroptosis in lung adenocarcinoma cells.

Autor: Xu X; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Cui J; Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Wang H; School of Public Health, Shanghai Jiao Tong University School of Medicine, 200025, China., Ma L; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Zhang X; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Guo W; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Xue X; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Wang Y; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Qiu S; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Tian X; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Miao Y; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Wu M; Shanghai University of Traditional Chinese Medicine, 201203, China., Yu Y; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China., Xu Y; Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, PR China., Wang J; Department of Clinical Laboratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.; Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 200030, China.; College of Medical Technology, Shanghai Jiao Tong University School of Medicine, 200025, China., Qiao Y; School of Public Health, Shanghai Jiao Tong University School of Medicine, 200025, China.

Publikováno v: Materials today. Bio [Mater Today Bio] 2022 Nov 24; Vol. 17, pp. 100503. Date of Electronic Publication: 2022 Nov 24 (Print Publication: 2022).