Zobrazeno 1 - 10
of 662
pro vyhledávání: '"WT1 gene"'
Publikováno v:
罕见病研究, Vol 3, Iss 1, Pp 63-76 (2024)
ObjectiveThis study aims to explore the association between different genotypes of WT1 gene variations and the phenotypes of Denys-Drash syndrome (DDS) and Frasier syndrome (FS).MethodsThrough searching and summarizing the case information of WT1 gen
Externí odkaz:
https://doaj.org/article/58f5dcd5368f4c4d8fb6a3e7f2d12f3a
Autor:
Sonia Ahmed, Mariam Elsherif, Dina Yassin, Nahla Elsharkawy, Ayman S. Mohamed, Nouran Yasser, Amr Elnashar, Hanafy Hafez, Edward A. Kolb, Alaa Elhaddad
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMolecular testing plays a pivotal role in monitoring measurable residual disease (MRD) in acute myeloid leukemia (AML), aiding in the refinement of risk stratification and treatment guidance. Wilms tumor gene 1 (WT1) is frequently upregulat
Externí odkaz:
https://doaj.org/article/b8f5691c0581409d84e6d241e1945e4b
Publikováno v:
Journal of the Pakistan Medical Association, Vol 74, Iss 1 (2023)
Focal segmental glomerulosclerosis (FSGS) can cause proteinuria and loss of kidney function, leading to end-stage renal disease (ESRD). Podocyte injury is the central pathophysiological mechanism of hereditary FSGS. Numerous mutations in genes encodi
Externí odkaz:
https://doaj.org/article/ec45c4322dbf4c449236770c4910231e
Autor:
Maria Tereza Martins Ferrari, Felipe Martins Elias, Nathalia Lisboa Rosa Almeida Gomes, Rafael Loch Batista, José Antonio Diniz Faria, Jr, Mirian Yumie Nishi, Berenice Bilharinho de Mendonca, Sorahia Domenice
Publikováno v:
Endocrine and Metabolic Science, Vol 13, Iss , Pp 100143- (2023)
The Wilms tumor suppressor gene (WT1) is a transcription factor with a wide array of functions, that affects the differentiation and survival of several cell types in different organs. It plays a special role in renal and gonadal development, organs
Externí odkaz:
https://doaj.org/article/3889e3b9d7dd4efb8c6591e58f520488
Autor:
Han Cui, Haoyu Zhu, Wenzhuo Ban, Yulin Li, Ruyi Chen, Lingli Li, Xiaoling Zhang, Kaili Chen, Hongyan Xu
Publikováno v:
Animals, Vol 14, Iss 3, p 508 (2024)
Zygote arrest-1 (Zar1) and Wilms’ tumor 1 (Wt1) play an important role in oogenesis, with the latter also involved in testicular development and gender differentiation. Here, Lczar1 and Lcwt1b were identified in Asian seabass (Lates calcarifer), a
Externí odkaz:
https://doaj.org/article/78b078bc875a4941b15e465005ea9498
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionThis study aimed to analyze the clinical characteristics of nephropathy associated with WT1 gene mutations in Chinese children and explore the relationship between genotype and clinical phenotype.MethodsCases diagnosed at the Guangzhou Wo
Externí odkaz:
https://doaj.org/article/7774663ea7514194b6d4c74b5207373a
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Isolated steroid-resistant nephrotic syndrome (ISRNS) is caused by mutations in the Wilms’ tumor-1 (WT1) gene, which encodes glomerular podocytes and podocyte slit diaphragm.We report a novel 8-year-old female patient with ISRNS
Externí odkaz:
https://doaj.org/article/184ded5a26524ea0aa8e9617c59b79d8
Autor:
Sneha Arya, Sandeep Kumar, Anurag R Lila, Vijaya Sarathi, Saba Samad Memon, Rohit Barnabas, Hemangini Thakkar, Virendra A Patil, Nalini S Shah, Tushar R Bandgar
Publikováno v:
Endocrine Connections, Vol 10, Iss 12, Pp 1522-1530 (2021)
Objective: The literature regarding gonadoblastoma risk in exonic Wilms’ tumor suppressor gene (WT1) pathogenic variants is sparse. The aim of this study is to describe the phenotypic and genotypic characteristics of Asian–Indian patients with WT
Externí odkaz:
https://doaj.org/article/d3610c6215ae47c79ec86e412be537aa
Publikováno v:
Asian Journal of Surgery, Vol 46, Iss 3, Pp 1313-1314 (2023)
Externí odkaz:
https://doaj.org/article/6dee023145874fc4ab698cf946dc62c8
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 165-171 (2020)
Vaccines have been used to fight and protect against infectious diseases for centuries. With the emergence of immunotherapy in cancer treatment, researchers began investigating vaccines that could be used against cancer, especially against tumors tha
Externí odkaz:
https://doaj.org/article/97954063819241e4a5892e2413b55ecc