Zobrazeno 1 - 10
of 231
pro vyhledávání: '"WILMA K. OLSON"'
Publikováno v:
Life, Vol 12, Iss 5, p 759 (2022)
DNA carries more than the list of biochemical ingredients that drive the basic functions of living systems. The sequence of base pairs includes a multitude of structural and energetic signals, which determine the degree to which the long, threadlike
Externí odkaz:
https://doaj.org/article/6a86a8b72db2478e928483e7d71c3558
Autor:
Jingqian Liu, Syukri Shukor, Shuxiang Li, Alfred Tamayo, Lorenzo Tosi, Benjamin Larman, Vikas Nanda, Wilma K. Olson, Biju Parekkadan
Publikováno v:
Biomolecules, Vol 9, Iss 5, p 199 (2019)
Multiplexed cloning of long DNA sequences is a valuable technique in many biotechnology applications, such as long-read genome sequencing and the creation of open reading frame (ORF) libraries. Long-adapter single-stranded oligonucleotide (LASSO) pro
Externí odkaz:
https://doaj.org/article/dea9f961bad44a3e9bab60086885a204
Publikováno v:
Biophysical Journal. 121:4749-4758
The proteins that bind double-helical DNA present various microenvironments that sense and/or induce signals in the genetic material. The high-resolution structures of protein-DNA complexes reveal the nature of both the microenvironments and the conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f351032c7ba4e251e5bbc867b09cfc79
https://doi.org/10.1016/j.bpj.2022.11.019
https://doi.org/10.1016/j.bpj.2022.11.019
Autor:
Nicole A. Becker, Justin P. Peters, Tanya L. Schwab, Louis J. Maher, David H. Tse, Karl J. Clark, Robert T. Young, Wilma K. Olson
Publikováno v:
Nucleic Acids Research
Architectural proteins alter the shape of DNA. Some distort the double helix by introducing sharp kinks. This can serve to relieve strain in tightly-bent DNA structures. Here, we design and test artificial architectural proteins based on a sequence-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4f94e27d8ca62719d6d5daa3ec620d
http://europepmc.org/articles/PMC8501960
http://europepmc.org/articles/PMC8501960
Autor:
Seyed Ahmad Sabok-Sayr, Wilma K. Olson
Publikováno v:
Journal of physics. A, Mathematical and theoretical. 53(43)
We introduce an analytical method to generate the pathway of a closed protein-bound DNA minicircle. We develop an analytical equation to connect two open curves smoothly and use the derived expressions to join the ends of two helical pathways and for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79132870220cd18ebedb69282e8a449e
https://pubmed.ncbi.nlm.nih.gov/36062023
https://pubmed.ncbi.nlm.nih.gov/36062023
Autor:
Wilma K. Olson, Nicolas Clauvelin
Publikováno v:
J Phys Chem B
The binding of proteins onto DNA contributes to the shaping and packaging of the genome as well as to the expression of specific genetic messages. With a view to understanding the interplay between the presence of proteins and the deformation of DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ae517a8111356b45865f368bb122db
https://doi.org/10.1021/acs.jpcb.0c11612
https://doi.org/10.1021/acs.jpcb.0c11612
Publikováno v:
Nucleic Acids Research
Web 3DNA (w3DNA) 2.0 is a significantly enhanced version of the widely used w3DNA server for the analysis, visualization, and modeling of 3D nucleic-acid-containing structures. Since its initial release in 2009, the w3DNA server has continuously serv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f5e1ed3043aabb3c0b1b587ff25878
https://doi.org/10.1093/nar/gkz394
https://doi.org/10.1093/nar/gkz394
Autor:
Stefjord Todolli, Abigail S. Watkins, John Yager, Wilma K. Olson, Antonio Bu Sha, Robert T. Young
Publikováno v:
J Mol Biol
While nucleosomes are dynamic entities that must undergo structural deformations to perform their functions, the general view from available high-resolution structures is a largely static one. Even though numerous examples of twist defects have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685f2e8dac20090ef9e9c619c6ff46bc
https://europepmc.org/articles/PMC8380738/
https://europepmc.org/articles/PMC8380738/
Publikováno v:
J Mol Biol
Computational modeling of nucleic acids plays an important role in molecular biology, enhancing our general understanding of the relationship between structure and function. Biophysical studies have provided a wealth of information on how double-heli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56116a73c0955eabe423572c08333177
https://doi.org/10.1016/j.jmb.2022.167558
https://doi.org/10.1016/j.jmb.2022.167558
Autor:
Olga I. Kulaeva, Wilma K. Olson, Ekaterina V. Nizovtseva, Yury S. Polikanov, Y V Postnikov, Vasily M. Studitsky, Nicolas Clauvelin
Publikováno v:
Молекулярная биология. 53:1038-1048
Transcriptional enhancers in the cell nuclei typically interact with the target promoters in cis over long stretches of chromatin, but the mechanism of this communication remains unknown. Previously we have developed a defined in vitro system for qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6599d933274387080325d174418f7a84
https://doi.org/10.1134/s0026898419060132
https://doi.org/10.1134/s0026898419060132