Zobrazeno 1 - 10
of 233
pro vyhledávání: '"WILLIAM L. McGUIRE"'
Autor:
William L. McGuire
Breast cancer continues to be a major problem. In Volume 1 of this series we dealt exclusively with topics concerned with therapy. In Volume 2 we explored various aspects of experimental biology which are critical to our developing better methods of
Autor:
William L. McGuire
This is the fourth book in a series dealing with breast cancer. Volumes 1-3 were concerned with treatment, experimental biology, and a number of varied timely topics. The present volume continues to review the breast cancer field in the broadest sens
Immunohistochemistry on Histological Sections from Small (50 mg) Samples of Pulverized Breast Cancer
Publikováno v:
Journal of Histotechnology. 16:117-120
A method is described for making histological sections of tumor pellets prepared from very small particulate samples of breast cancer originally pulverized for biochemical analysis of estrogen and progesterone receptors. Pulverizing the frozen tumor
Publikováno v:
Journal of Cellular Biochemistry. 52:196-205
The insulin-like growth factors (IGFs) have been implicated in the growth regulation of human breast cancer. Since the IGFs are associated with specific binding proteins (IGFBPs) which may modulate receptor/ligand interactions, production of IGFBPs b
Publikováno v:
Cancer. 71:2499-2506
Autor:
Patricia Vendely, B S George Pounds, Douglas Harrington, William L. McGuire, B A Teri Oldaker, Gary M. Clark, R B A Charlotte Wenger, Marilyn A. Owens, B A Susan Beardslee, Murugan R. Pandian
Publikováno v:
Cancer. 71:2157-2162
A large group of patients with node-positive breast cancer was divided into a training set (n = 851) and a validation set (n = 432) to demonstrate techniques for integrating steroid hormone receptor status, DNA flow cytometric findings, and other pro
Publikováno v:
Journal of Cellular Biochemistry. 51:135-139
It is fairly well accepted that the presence of estrogen receptor (ER) identifies those breast cancer patients with a lower risk of relapse and better overall survival [Clark and McGuire, 1988], and the measurement of ER has become a standard assay i
Publikováno v:
Cytometry. 14:74-80
A pattern recognition system based on Neural Network Analysis, a form of artificial intelligence, was used to search DNA flow cytometry histograms for features that correlated with breast cancer patients' risk of relapse. DNA flow cytometry histogram
Autor:
Gary M. Clark, Suzanne A. W. Fuqua, Daniel R. Ciocca, C K Osborne, C. A. Encarnacion, William L. McGuire
Publikováno v:
Breast Cancer Research and Treatment. 26:237-246
Estrogen (ER) and progesterone receptor (PgR) positive breast tumors often respond to tamoxifen, but ultimately progress as they become tamoxifen resistant. An accurate assessment of receptor status in specimens from tamoxifen-resistant patients coul
Autor:
D. Craig Allred, Pascal Pujol, William L. McGuire, Suzanne A. W. Fuqua, Gary M. Clark, Richard M. Elledge
Publikováno v:
Breast Cancer Research and Treatment. 26:225-235
Mutations in the p53 gene can play a role in the transformation of normal to malignant cells. Because these mutations are more frequently reported later in the course of transformation, their presence could reflect a greater malignant potential of th