Zobrazeno 1 - 10
of 1 418
pro vyhledávání: '"WILLIAM D. FRASER"'
Autor:
Cyrus Cooper, David A Jolliffe, Adrian R Martineau, Linda-Gail Bekker, Nicholas C Harvey, William D Fraser, Keren Middelkoop, Jonathan Tang, Anna K Coussens, Robert J Wilkinson, Neil Walker, Lisa Micklesfield, Justine Stewart, Amy E Mendham, James Nuttall, Waheedullah Momand
Publikováno v:
BMJ Paediatrics Open, Vol 8, Iss 1 (2024)
Objective To determine whether weekly oral vitamin D supplementation influences growth, body composition, pubertal development or spirometric outcomes in South African schoolchildren.Design Phase 3 double-blind randomised placebo-controlled trial.Set
Externí odkaz:
https://doaj.org/article/07f8e889db6445a88839aa69107c9b5e
Autor:
Sarah J Myers, Rebecca L Knight, Sophie L Wardle, Kirsty AM Waldock, Thomas J O'Leary, Richard K Jones, Paul E Muckelt, Anton Eisenhauer, Jonathan CY Tang, William D Fraser, Julie P Greeves
Publikováno v:
JMIR Research Protocols, Vol 13, p e50542 (2024)
BackgroundWomen of reproductive age experience cyclical variation in the female sex steroid hormones 17β-estradiol and progesterone during the menstrual cycle that is attenuated by some hormonal contraceptives. Estrogens perform a primary function i
Externí odkaz:
https://doaj.org/article/064a6adef4f2402da03638a0463c1e80
Autor:
Keren Middelkoop, Justine Stewart, Neil Walker, Carmen Delport, David A. Jolliffe, Anna K. Coussens, James Nuttall, Jonathan C.Y. Tang, William D. Fraser, Christopher J. Griffiths, Geeta Trilok Kumar, Suzanne Filteau, Richard L. Hooper, Robert J. Wilkinson, Linda-Gail Bekker, Adrian R. Martineau
Publikováno v:
International Journal of Infectious Diseases, Vol 134, Iss , Pp 63-70 (2023)
ABSTRACT: Objectives: To determine whether weekly oral supplementation with 10,000 IU vitamin D3 for 3 years reduces the risk of sensitization to M. tuberculosis in South African schoolchildren aged 6-11 years with negative QuantiFERON-tuberculosis (
Externí odkaz:
https://doaj.org/article/f36b708fb8694610b7528f5eaa36a2a4
Autor:
Charlotte V. Coombs, Sophie L. Wardle, Rukshana Shroff, Anton Eisenhauer, Jonathan C. Y. Tang, William D. Fraser, Julie P. Greeves, Thomas J. O’Leary
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-8 (2023)
Abstract Background Military field exercises are characterised by high volumes of exercise and prolonged periods of load carriage. Exercise can decrease circulating serum calcium and increase parathyroid hormone and bone resorption. These disturbance
Externí odkaz:
https://doaj.org/article/5f6b17e297114023a52d1c84495e7b8c
Autor:
Sophia Rahimi, Xiaojian Shao, Donovan Chan, Josée Martel, Anick Bérard, William D. Fraser, Marie-Michelle Simon, Tony Kwan, Guillaume Bourque, Jacquetta Trasler
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-21 (2023)
Abstract Background Children conceived through assisted reproduction are at an increased risk for growth and genomic imprinting disorders, often linked to DNA methylation defects. It has been suggested that assisted reproductive technology (ART) and
Externí odkaz:
https://doaj.org/article/e1f7960f8a21419ea087d473363faa22
Autor:
Sherri Lee Jones, Victoria De Braga, Christina Caccese, Jimin Lew, Guillaume Elgbeili, Natalie Castellanos-Ryan, Sophie Parent, Gina Muckle, Catherine M. Herba, William D. Fraser, Simon Ducharme, Julia Barnwell, Jacquetta Trasler, Jean R. Séguin, Tuong-Vi Nguyen, Tina C. Montreuil
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2024)
IntroductionThis study examined (1) whether measures of paternal anxious and depressive symptoms collected prenatally and during a follow-up assessment when the child was in middle childhood, predict child neuroendocrine outcomes, and (2) whether neu
Externí odkaz:
https://doaj.org/article/dc05b50fb63f42f89d1974e3737a796e
Autor:
Noémie Tanguay, Nadia Abdelouahab, Marie-Noelle Simard, Jean R. Séguin, Isabelle Marc, Catherine M. Herba, Andrea A. N. MacLeod, Yohann Courtemanche, William D. Fraser, Gina Muckle
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Approximately 5.5% of pregnant women take antidepressants. Studies on prenatal exposure to antidepressants reported no association with child cognition, and inconsistent results with motor function and language development. A limitation
Externí odkaz:
https://doaj.org/article/b2882bbafb6044e89448032c5e84b3fe
Autor:
Sherri Lee Jones, Christina Caccese, Kelsey P. Davis, Jimin Lew, Guillaume Elgbeili, Catherine M. Herba, Julia Barnwell, Cindy Hénault Robert, Isabella Gavanski, Kristin Horsley, William D. Fraser, Deborah Da Costa, Jean R. Séguin, Tuong-Vi Nguyen, Tina C. Montreuil
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
IntroductionPaternal mental health has been associated with adverse consequences on offspring psychosocial development, and family environmental factors may partly explain those associations. To clarify this, we need comprehensive prospective studies
Externí odkaz:
https://doaj.org/article/3f9c805d1aaf4d5ea751d851186db699
Autor:
Rose A. Schmidt, Tina W. Wey, Kelly D. Harding, Isabel Fortier, Stephanie Atkinson, Suzanne Tough, Nicole Letourneau, Julia A. Knight, William D. Fraser, Alan Bocking
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background As a teratogen, alcohol exposure during pregnancy can impact fetal development and result in adverse birth outcomes. Despite the clinical and social importance of prenatal alcohol use, limited routinely collected information or ep
Externí odkaz:
https://doaj.org/article/f324c3d8008c4928a2f9f53d709d61ba
Autor:
Darrell Green, Archana Singh, Victoria L. Tippett, Luke Tattersall, Karan M. Shah, Chileleko Siachisumo, Nicole J. Ward, Paul Thomas, Simon Carter, Lee Jeys, Vaiyapuri Sumathi, Iain McNamara, David J. Elliott, Alison Gartland, Tamas Dalmay, William D. Fraser
Publikováno v:
Journal of Bone Oncology, Vol 39, Iss , Pp 100474- (2023)
Primary bone cancer (PBC) comprises several subtypes each underpinned by distinctive genetic drivers. This driver diversity produces novel morphological features and clinical behaviour that serendipitously makes PBC an excellent metastasis model. Her
Externí odkaz:
https://doaj.org/article/4879f410a6f04bfca0f55c50fb4bf523