Zobrazeno 1 - 10
of 368
pro vyhledávání: '"WILLIAM A. SPENCER"'
Autor:
Yixiao Wang, Silke Becker, Stella Finkelstein, Frank M. Dyka, Haitao Liu, Mark Eminhizer, Ying Hao, Richard S. Brush, William J. Spencer, Vadim Y. Arshavsky, John D. Ash, Jianhai Du, Martin-Paul Agbaga, Frans Vinberg, Jessica M. Ellis, Ekaterina S. Lobanova
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The retina is light-sensitive neuronal tissue in the back of the eye. The phospholipid composition of the retina is unique and highly enriched in polyunsaturated fatty acids, including docosahexaenoic fatty acid (DHA). While it is generally
Externí odkaz:
https://doaj.org/article/ad85367e74fe4ef684827fbc22b57206
Autor:
William A. Spencer, Frances K. Kochan
Publikováno v:
Education Policy Analysis Archives, Vol 8, p 9 (2000)
The purpose of this research was to determine the status of women administrators in the Alabama in terms of demographic and career patterns. A survey was sent to all principals in Alabama. Five hundred-fifty, or 42% of the principals responded. In Al
Externí odkaz:
https://doaj.org/article/39ebf9f7ffed448da69c31f0d7808168
Autor:
William J. Spencer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The release of extracellular vesicles is observed across numerous cell types and serves a range of biological functions including intercellular communication and waste disposal. One cell type which stands out for its robust capacity to release extrac
Externí odkaz:
https://doaj.org/article/553bb7be478d42bebb5e6cba7a9227f5
Autor:
Thomas A. Ray, Kelly Cochran, Chris Kozlowski, Jingjing Wang, Graham Alexander, Martha A. Cady, William J. Spencer, Philip A. Ruzycki, Brian S. Clark, Annelies Laeremans, Ming-Xiao He, Xiaoming Wang, Emily Park, Ying Hao, Alessandro Iannaccone, Gary Hu, Olivier Fedrigo, Nikolai P. Skiba, Vadim Y. Arshavsky, Jeremy N. Kay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Here the authors present an approach that can reveal the full complement of mRNA isoforms encoded by individual genes, and they identify a major isoform of the retinal degeneration gene CRB1 which functions at the cell-cell junctions of the outer lim
Externí odkaz:
https://doaj.org/article/d7eafb0bbaa4448cab111eaa3196f3ce
Autor:
William J. Spencer, Nicholas F. Schneider, Tylor R. Lewis, Carson M. Castillo, Nikolai P. Skiba, Vadim Y. Arshavsky
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The photoreceptor outer segment is a modified cilium filled with hundreds of flattened “disc” membranes responsible for efficient light capture. To maintain photoreceptor health and functionality, outer segments are continuously renewed through t
Autor:
Nikolai P. Skiba, Tylor R. Lewis, William J. Spencer, Carson M. Castillo, Andrej Shevchenko, Vadim Y. Arshavsky
Publikováno v:
bioRxiv
Photoreceptor cells generate neuronal signals in response to capturing light. This process, called phototransduction, takes place in a highly specialized outer segment organelle. There are significant discrepancies in the reported amounts of many pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc5584ff6aaf61d1d0a12a05650b6ca
https://europepmc.org/articles/PMC9882265/
https://europepmc.org/articles/PMC9882265/
The photoreceptor outer segment is a modified cilium filled with hundreds of flattened “disc” membranes responsible for efficient light capture. To maintain photoreceptor health and functionality, outer segments are continuously renewed through t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8153dbd53ad378db9c1375794a6e6e0d
https://doi.org/10.1101/2022.11.21.517374
https://doi.org/10.1101/2022.11.21.517374
Autor:
William C. Spencer, Evan S. Deneris
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The brain serotonin (5-hydroxytryptamine; 5-HT) system has been extensively studied for its role in normal physiology and behavior, as well as, neuropsychiatric disorders. The broad influence of 5-HT on brain function, is in part due to the vast conn
Externí odkaz:
https://doaj.org/article/c68c60ae3ef64bad8aeb08d6326cb5b9
Autor:
Xiaoming Wang, Thomas A. Ray, Jingjing Wang, Alessandro Iannaccone, Nikolai P. Skiba, Chris Kozlowski, Jeremy N. Kay, William J. Spencer, Annelies Laeremans, Vadim Y. Arshavsky, Martha A. Cady, Olivier Fedrigo, Brian S. Clark, Gary Hu, Kelly Cochran, Ming-Xiao He, Graham Alexander, Philip A. Ruzycki, Emily Park, Ying Hao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications
Nature Communications
Genes encoding cell-surface proteins control nervous system development and are implicated in neurological disorders. These genes produce alternative mRNA isoforms which remain poorly characterized, impeding understanding of how disease-associated mu