Zobrazeno 1 - 10
of 252
pro vyhledávání: '"WILHELM KRIZ"'
Autor:
Georg Hildenbrand, Philipp Metzler, Götz Pilarczyk, Vladimir Bobu, Wilhelm Kriz, Hiltraud Hosser, Jens Fleckenstein, Matthias Krufczik, Felix Bestvater, Frederik Wenz, Michael Hausmann
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190183 (2018)
Localization microscopy has shown to be capable of systematic investigations on the arrangement and counting of cellular uptake of gold nanoparticles (GNP) with nanometer resolution. In this article, we show that the application of specially modified
Externí odkaz:
https://doaj.org/article/d7627413ffd945108e322f3fa88279ec
Publikováno v:
The American Journal of Pathology. 192:1670-1682
The development of focal and segmental glomerulosclerosis (FSGS) as a consequence of glomerular hypertension resulting from arterial hypertension is widely considered a podocyte disease. However, the primary damage is encountered in the mesangium. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429de76a67d9f9812bd71fc19cababcc
https://doi.org/10.1016/j.ajpath.2022.08.007
https://doi.org/10.1016/j.ajpath.2022.08.007
Publikováno v:
Nephrology Dialysis Transplantation.
This review summarizes the pathomorphological sequences of nephron loss in human diabetic nephropathy (DN). The relevant changes may be derived from two major derangements. First, a failure in the turnover of the glomerular basement membrane (GBM) ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70615559e24baff7c8462792fd2aa459
https://doi.org/10.1093/ndt/gfad052
https://doi.org/10.1093/ndt/gfad052
Autor:
Hermann-Josef Gröne, Jana Löwen, Felix Bestvater, Wilhelm Kriz, Marie-Luise Groß-Weißmann, Elisabeth F. Gröne
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F600-F616
Based on analysis of 819 human biopsies, essential derangement in diabetic nephropathy consists of accumulation of worn-out glomerular basement membrane in the mesangium that may advance to global sclerosis. The most frequent pathway to nephron dropo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2fb854a0ad4739863393613ebce7c6
https://doi.org/10.1152/ajprenal.00669.2020
https://doi.org/10.1152/ajprenal.00669.2020
Autor:
Janos Peti-Peterdi, Kenton P. Arkill, Wilhelm Kriz, Georgina Gyarmati, Anne Riquier-Brison, Brigitte Kaissling, Ju-Young Moon, Nariman Ahmadi, Inderbir S. Gill, Urvi Nikhil Shroff, Dorinne Desposito, Christopher R. Neal
Publikováno v:
American Journal of Physiology-Renal Physiology. 320:F492-F504
Although macula densa (MD) cells are chief regulatory cells in the nephron with unique microanatomical features, they have been difficult to study in full detail due to their inaccessibility and limitations in earlier microscopy techniques. The prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c328e7f6a429ff98336dfae75c929067
https://doi.org/10.1152/ajprenal.00546.2020
https://doi.org/10.1152/ajprenal.00546.2020
Publikováno v:
American Journal of Physiology-Renal Physiology. 317:F399-F410
As shown in our previous paper (Kriz W, Löwen J, Federico G, van den Born J, Gröne E, Gröne HJ. Am J Physiol Renal Physiol 312: F1101–F1111, 2017), mesangial matrix expansion in diabetic nephropathy (DN) results for a major part from the accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db50d82a3da3ab4b2d017ad3a01ac7a
https://doi.org/10.1152/ajprenal.00617.2018
https://doi.org/10.1152/ajprenal.00617.2018
Autor:
Matthias Kretzler, Masataka Sunohara, Karlhans Endlich, Wilhelm Kriz, Norbert Gretz, Bettina Kränzlin, Nicole Endlich
Publikováno v:
Cellular and Molecular Biology. 65:84-88
Elevated mechanical stress in glomerular hypertension is thought to damage podocytes, the loss of which leads to development of glomerulosclerosis. Applying cDNA array analysis to mechanically stressed podocytes, we have recently identified TSG101 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e706843a8114f874d1ee2cec6288d807
https://doi.org/10.14715/cmb/2019.65.1.15
https://doi.org/10.14715/cmb/2019.65.1.15
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Diabetic nephropathy (DN) is the leading cause of end-stage-renal disease in western countries. Despite of innumerable studies undertaken to elucidate the pathogenesis of DN the underlying morphologic alterations have been insuffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f873566f8d204f395c1717455979442a
https://doi.org/10.1093/ndt/gfab078.006
https://doi.org/10.1093/ndt/gfab078.006
Autor:
Georgina Gyarmati, Kevin V. Lemley, Isao Shirato, Wilhelm Kriz, James L. Burford, János Peti-Peterdi
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 469:965-974
The development of podocyte injury and albuminuria in various glomerular pathologies is still incompletely understood due to technical limitations in studying the glomerular filtration barrier (GFB) in real-time. We aimed to directly visualize the ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2aa98fbffaaf7cf2a62b5147dff8ebb
https://doi.org/10.1007/s00424-017-2020-0
https://doi.org/10.1007/s00424-017-2020-0
Autor:
Kevin V. Lemley, Wilhelm Kriz
Publikováno v:
Kidney International. 91:1283-1286
Filtrate flow through the glomerular barrier produces shear stresses that tend to disconnect podocytes from the glomerular basement membrane. Forces are highest within the filtration slits. The slit diaphragm mechanically balances the lateral compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cffd562baba760350602d05ac1b9b8
https://doi.org/10.1016/j.kint.2017.02.032
https://doi.org/10.1016/j.kint.2017.02.032