Zobrazeno 1 - 10
of 243
pro vyhledávání: '"WESLEY WU"'
Autor:
Jule Goike, Ching-Lin Hsieh, Andrew P. Horton, Elizabeth C. Gardner, Ling Zhou, Foteini Bartzoka, Nianshuang Wang, Kamyab Javanmardi, Andrew Herbert, Shawn Abbassi, Xuping Xie, Hongjie Xia, Pei-Yong Shi, Rebecca Renberg, Thomas H. Segall-Shapiro, Cynthia I. Terrace, Wesley Wu, Raghav Shroff, Michelle Byrom, Andrew D. Ellington, Edward M. Marcotte, James M. Musser, Suresh V. Kuchipudi, Vivek Kapur, George Georgiou, Scott C. Weaver, John M. Dye, Daniel R. Boutz, Jason S. McLellan, Jimmy D. Gollihar
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract The ongoing evolution of SARS-CoV-2 into more easily transmissible and infectious variants has provided unprecedented insight into mutations enabling immune escape. Understanding how these mutations affect the dynamics of antibody-antigen in
Externí odkaz:
https://doaj.org/article/e176e0ac10fe413398cba9041336c98a
Autor:
Isobel Routledge, Adrienne Epstein, Saki Takahashi, Owen Janson, Jill Hakim, Elias Duarte, Keirstinne Turcios, Joanna Vinden, Kirk Sujishi, Jesus Rangel, Marcelina Coh, Lee Besana, Wai-Kit Ho, Ching-Ying Oon, Chui Mei Ong, Cassandra Yun, Kara Lynch, Alan H. B. Wu, Wesley Wu, William Karlon, Edward Thornborrow, Michael J. Peluso, Timothy J. Henrich, John E. Pak, Jessica Briggs, Bryan Greenhouse, Isabel Rodriguez-Barraquer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Population-based surveys are the gold standard for estimating seroprevalence but are expensive and often only capture a small geographic area or window of time. This study describes a new platform, SCALE-IT, for serosurveillance based on algorithmic
Externí odkaz:
https://doaj.org/article/2c73ad75f25940cfa9325487cf55c8e4
Autor:
Janie R. Byrum, Eric Waltari, Owen Janson, Syuan-Ming Guo, Jenny Folkesson, Bryant B. Chhun, Joanna Vinden, Ivan E. Ivanov, Marcus L. Forst, Hongquan Li, Adam G. Larson, Lena Blackmon, Ziwen Liu, Wesley Wu, Vida Ahyong, Cristina M. Tato, Krista M. McCutcheon, Rebecca Hoh, J. Daniel Kelly, Jeffrey N. Martin, Michael J. Peluso, Timothy J. Henrich, Steven G. Deeks, Manu Prakash, Bryan Greenhouse, Shalin B. Mehta, John E. Pak
Publikováno v:
Pathogens, Vol 12, Iss 5, p 671 (2023)
A multiplexed enzyme-linked immunosorbent assay (ELISA) that simultaneously measures antibody binding to multiple antigens can extend the impact of serosurveillance studies, particularly if the assay approaches the simplicity, robustness, and accurac
Externí odkaz:
https://doaj.org/article/d7bd915e61c04e7fb73fcb2422aa49e0
Autor:
Eric Song, Christopher M. Bartley, Ryan D. Chow, Thomas T. Ngo, Ruoyi Jiang, Colin R. Zamecnik, Ravi Dandekar, Rita P. Loudermilk, Yile Dai, Feimei Liu, Sara Sunshine, Jamin Liu, Wesley Wu, Isobel A. Hawes, Bonny D. Alvarenga, Trung Huynh, Lindsay McAlpine, Nur-Taz Rahman, Bertie Geng, Jennifer Chiarella, Benjamin Goldman-Israelow, Chantal B.F. Vogels, Nathan D. Grubaugh, Arnau Casanovas-Massana, Brett S. Phinney, Michelle Salemi, Jessa R. Alexander, Juan A. Gallego, Todd Lencz, Hannah Walsh, Anne E. Wapniarski, Subhasis Mohanty, Carolina Lucas, Jon Klein, Tianyang Mao, Jieun Oh, Aaron Ring, Serena Spudich, Albert I. Ko, Steven H. Kleinstein, John Pak, Joseph L. DeRisi, Akiko Iwasaki, Samuel J. Pleasure, Michael R. Wilson, Shelli F. Farhadian
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100288- (2021)
Summary: Individuals with coronavirus disease 2019 (COVID-19) frequently develop neurological symptoms, but the biological underpinnings of these phenomena are unknown. Through single-cell RNA sequencing (scRNA-seq) and cytokine analyses of cerebrosp
Externí odkaz:
https://doaj.org/article/13598675c04e4b9aa6e8c523385b4bf1
Autor:
Kirthana M. V. Sindhe, Wesley Wu, Jenny Legac, Yong-Kang Zhang, Eric E. Easom, Roland A. Cooper, Jacob J. Plattner, Yvonne R. Freund, Joseph L. DeRisi, Philip J. Rosenthal
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT New antimalarial drugs are needed. The benzoxaborole AN13762 showed excellent activity against cultured Plasmodium falciparum, against fresh Ugandan P. falciparum isolates, and in murine malaria models. To gain mechanistic insights, we selec
Externí odkaz:
https://doaj.org/article/f9067457c1d346e893d1e74840fb86f1
Autor:
Wibbens, Phebo D.1 (AUTHOR), Koo, Wesley Wu-Yi2 (AUTHOR), McGahan, Anita M.3 (AUTHOR) anita.mcgahan@rotman.utoronto.ca
Publikováno v:
PLoS ONE. 12/29/2020, Vol. 15 Issue 12, p1-19. 19p.
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244177 (2020)
This paper reports the results of a Bayesian analysis on large-scale empirical data to assess the effectiveness of eleven types of COVID-control policies that have been implemented at various levels of intensity in 40 countries and U.S. states since
Externí odkaz:
https://doaj.org/article/bea7ca3d875e4d23b46dd0cfb8b48a8e
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology. 15:455-469
Scarring is a dire consequence of acne vulgaris. Particularly, atrophic acne scarring is highly prevalent among young adults, and its physical and psychological effects can persist throughout their lives if left untreated. This literature review will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e8fb5fd4869d93123e70ae318b8dd3
https://doi.org/10.2147/ccid.s350040
https://doi.org/10.2147/ccid.s350040
Autor:
Brian L. Hie, Varun R. Shanker, Duo Xu, Theodora U. J. Bruun, Payton A. Weidenbacher, Shaogeng Tang, Wesley Wu, John E. Pak, Peter S. Kim
Publikováno v:
Nature Biotechnology.
Natural evolution must explore a vast landscape of possible sequences for desirable yet rare mutations, suggesting that learning from natural evolutionary strategies could guide artificial evolution. Here we report that general protein language model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1fb6b62a9f8f2d6ca47ab61260b6c6d
https://doi.org/10.1038/s41587-023-01763-2
https://doi.org/10.1038/s41587-023-01763-2
Autor:
Matthew T. Laurie, Corin V. White, Hanna Retallack, Wesley Wu, Matthew S. Moser, Judy A. Sakanari, Kenny Ang, Christopher Wilson, Michelle R. Arkin, Joseph L. DeRisi
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Balamuthia mandrillaris is a pathogenic free-living amoeba that causes a rare but almost always fatal infection of the central nervous system called granulomatous amoebic encephalitis (GAE). Two distinct forms of B. mandrillaris—a prolifer
Externí odkaz:
https://doaj.org/article/dc0b924a0e4e4116b009021d93f76abd