Zobrazeno 1 - 10
of 24
pro vyhledávání: '"WEN-I HUANG"'
Autor:
WEN-I HUANG, 黃文益
高階經營管理碩士在職專班(EMBA)
103
This study is to investigate marketing strategies for the Medicine company, which is an own brand of face care products sales company. The Medicine company is established 5 years ago with a sma
103
This study is to investigate marketing strategies for the Medicine company, which is an own brand of face care products sales company. The Medicine company is established 5 years ago with a sma
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/5qne5y
Autor:
Wen-i Huang, 黃文怡
102
This action research aims to investigate the effectiveness of applying discovery teaching method to improve senior high scehool students’ attitude toward science and their scientfic literacy—identify scientific issues, use scientific evi
This action research aims to investigate the effectiveness of applying discovery teaching method to improve senior high scehool students’ attitude toward science and their scientfic literacy—identify scientific issues, use scientific evi
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/66fvzn
Autor:
Ming-Chi Lu, Yen-Wen Tseng, Yan-Lin Zhong, Chen-An Chan, Che-An Chiu, Wen-I Huang, Chia-Ju Liu, Ming-Chung Ho
Publikováno v:
Sensors and Materials. 34:1211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52f3b181c4e51cd2d12135b83158861a
https://doi.org/10.18494/sam3490
https://doi.org/10.18494/sam3490
Autor:
Ting-Ting Li, Wen-I Huang, Keng-Chang Tsai, Din-Chi Chiu, Yin-Chen Tseng, Jia-Tsrong Jan, Peng-Cheng Wang, Ting-Jen Cheng, Jim-Min Fang
Publikováno v:
European Journal of Medicinal Chemistry. 145:224-234
Peramivir is an efficacious neuraminidase (NA) inhibitor for treatment of influenza by intravenous administration. However, the efficacy of peramivir toward the H275Y mutant is appreciably reduced. To address this drawback, conjugation of peramivir w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30bd60e97a9905875a6b439e13657b73
https://doi.org/10.1016/j.ejmech.2017.12.072
https://doi.org/10.1016/j.ejmech.2017.12.072
Publikováno v:
Organic & Biomolecular Chemistry. 15:9910-9922
Peramivir is an effective anti-influenza drug in the clinical treatment of influenza, but its efficacy toward the H275Y mutant is reduced. The previously reported cocrystal structures of inhibitors in the mutant neuraminidase (NA) suggest that the hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0ea2a4f2c030eb24ecf1cc4872d559
https://doi.org/10.1039/c7ob02374j
https://doi.org/10.1039/c7ob02374j
Autor:
Chung-Ming Sun, Ting Jen Cheng, Yih Shyun E. Cheng, Olivia A. Lin, Suz Ting Wang, Yufeng J. Tseng, Wen I. Huang, Shi Yun Wang, Meng I. Lin, Chia Hsin Lee, Prasad S. Dangate, Bo-Han Su, Wen Chun Wu
Publikováno v:
European Journal of Medicinal Chemistry. 102:477-486
The influenza nucleoprotein (NP) is a single-strand RNA-binding protein and the core of the influenza ribonucleoprotein (RNP) particle that serves many critical functions for influenza replication. NP has been considered as a promising anti-influenza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78783615dd67bb509ed083044e5182eb
https://doi.org/10.1016/j.ejmech.2015.08.016
https://doi.org/10.1016/j.ejmech.2015.08.016
Autor:
Wen-I Huang, Bei-Tao Hong, Yih-Shyun E. Cheng, Chi-Huey Wong, Keng-Chang Tsai, Chun-Lin Chen, Shi-Yun Wang, Jim-Min Fang
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:6647-6654
Tamiflu, the ethyl ester form of oseltamivir carboxylic acid (OC), is the first orally available anti-influenza drug for the front-line therapeutic option. In this study, the OC-hydroxamates, OC-sulfonamides and their guanidino congeners (GOC) were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36938f49b2b4a0ea4e043b5f275c4a58
https://doi.org/10.1016/j.bmc.2014.10.005
https://doi.org/10.1016/j.bmc.2014.10.005
Autor:
Charng-Sheng Tsai, Hsin-Yung Yen, Meng-I Lin, Tsung-I Tsai, Shi-Yun Wang, Wen-I Huang, Tsui-Ling Hsu, Yih-Shyun E. Cheng, Jim-Min Fang, Chi-Huey Wong
Publikováno v:
Proceedings of the National Academy of Sciences. 110:2466-2471
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) containing an alkyne group was shown to be a mechanism-based target-specific irreversible inhibitor of sialidases. The ester-protected analog DFSA (PDFSA) is a membrane-permeable precursor of DFSA designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd10f19e998cc2c3a085dad826cd43d
https://doi.org/10.1073/pnas.1222183110
https://doi.org/10.1073/pnas.1222183110
Autor:
Shi-Yun Wang, Chi-Huey Wong, Wen-I Huang, Jim-Min Fang, Ting-Jen R. Cheng, Peng-Cheng Wang, Keng-Chang Tsai, Yin-Chen Tseng, Yih-Shyun E. Cheng
Publikováno v:
Journal of medicinal chemistry. 59(11)
Peramivir is a potent neuraminidase (NA) inhibitor for treatment of influenza infection by intravenous administration. By replacing the carboxylate group in peramivir with a phosphonate group, phosphono-peramivir (6a), the dehydration and deoxy deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8526b66e027d9711c181b27fb815044d
https://pubmed.ncbi.nlm.nih.gov/27167096
https://pubmed.ncbi.nlm.nih.gov/27167096