Effect of IGF1Rβ Subunit Mutants on Proliferation, Migration and Apoptosis of Human Osteosarcoma Cells

Autor: WEN Zhongchi, LIU Tuozhou, HE Hongbo, ZHANG Can, LIU Yupeng, LIAO Zhan, ZENG Liyi

Publikováno v: Zhongliu Fangzhi Yanjiu, Vol 49, Iss 5, Pp 390-395 (2022)

Objective To investigate the effect of IGF1R β subunit mutants sb-IGF1R and ma-IGF1R on the biological behavior of osteosarcoma 143B cells. Methods We designed and constructed sb-IGF1R and ma-IGF1R fragments. They were cloned into adenovirus AdEasy

Externí odkaz: https://doaj.org/article/972fad471b70490c87c06450ff3be668

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Ferroptosis contributes to immunosuppression.

Autor: He N; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China.; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, China.; National Medicine Functional Experimental Teaching Center, Changsha, 410008, China., Yuan D; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China., Luo M; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China.; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, China.; National Medicine Functional Experimental Teaching Center, Changsha, 410008, China., Xu Q; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China.; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, China.; National Medicine Functional Experimental Teaching Center, Changsha, 410008, China., Wen Z; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China.; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, China.; National Medicine Functional Experimental Teaching Center, Changsha, 410008, China., Wang Z; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China.; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, China.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, China.; National Medicine Functional Experimental Teaching Center, Changsha, 410008, China., Zhao J; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China. steelzj@csu.edu.cn.; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, China. steelzj@csu.edu.cn.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, China. steelzj@csu.edu.cn.; National Medicine Functional Experimental Teaching Center, Changsha, 410008, China. steelzj@csu.edu.cn., Liu Y; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, China. liu1977ying@126.com.; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, 410008, China. liu1977ying@126.com.; Sepsis Translational Medicine Key Lab of Hunan Province, Changsha, 410008, China. liu1977ying@126.com.; National Medicine Functional Experimental Teaching Center, Changsha, 410008, China. liu1977ying@126.com.

Publikováno v: Frontiers of medicine [Front Med] 2024 Nov 19. Date of Electronic Publication: 2024 Nov 19.