Zobrazeno 1 - 10
of 117
pro vyhledávání: '"WEI-JIANG ZHAO"'
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36986- (2024)
The tumor immune microenvironment (TIME) significantly influences cancer progression and treatment. This study sought to uncover novel TIME-related glioma biomarkers to advance antitumor immunotherapies by integrating data from sequencing of bulk RNA
Externí odkaz:
https://doaj.org/article/89440174a05748b3b4bc610999eb7f18
Autor:
Kai-Ye Hua, Wei-Jiang Zhao
Publikováno v:
Folia Neuropathologica, Vol 61, Iss 1, Pp 8-15 (2022)
Alzheimer’s disease (AD), also known as senile dementia, is a degenerative disease of the central nervous system and is characterized by insidious onset and a chronic progressive course. It is the most common type of senile dementia. Studies have p
Externí odkaz:
https://doaj.org/article/5a5eeede7cbf4ff0b9fca94c1954d4fb
Autor:
Mei-Xuan Zhang, Hui Hong, Yun Shi, Wen-Yan Huang, Yi-Meng Xia, Lu-Lu Tan, Wei-Jiang Zhao, Chen-Meng Qiao, Jian Wu, Li-Ping Zhao, Shu-Bing Huang, Xue-Bing Jia, Yan-Qin Shen, Chun Cui
Publikováno v:
Brain Sciences, Vol 14, Iss 4, p 300 (2024)
Parkinson’s disease (PD) is characterized not only by motor symptoms but also by non-motor dysfunctions, such as olfactory impairment; the cause is not fully understood. Our study suggests that neuronal loss and inflammation in brain regions along
Externí odkaz:
https://doaj.org/article/b97a6b45c17c450a817bf7274fd593d1
Autor:
Chen-Meng Qiao, Wen-Yan Huang, Yu Zhou, Wei Quan, Gu-Yu Niu, Ting Li, Mei-Xuan Zhang, Jian Wu, Li-Ping Zhao, Wei-Jiang Zhao, Chun Cui, Yan-Qin Shen
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 238 (2024)
Increasing evidence suggests that the gut microbiota may represent potential strategies for Parkinson’s disease (PD) treatment. Our previous research revealed a decreased abundance of Akkermansia muciniphila (Akk) in PD mice; however, whether Akk i
Externí odkaz:
https://doaj.org/article/770f2fcdb0064653b87c47e0372a4742
Autor:
Li-Ping Zhao, Jian Wu, Wei Quan, Yu Zhou, Hui Hong, Gu-Yu Niu, Ting Li, Shu-Bing Huang, Chen-Meng Qiao, Wei-Jiang Zhao, Chun Cui, Yan-Qin Shen
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Accumulative studies suggest that inflammatory bowel disease (IBD) may cause multiple central nervous system (CNS) pathologies. Studies have found that indoleamine-2,3-dioxygenase (IDO, rate-limiting enzyme of the kynurenine (Kyn) pathway) deficient
Externí odkaz:
https://doaj.org/article/5f29231e6cb143bebf7ecd53f2cd091b
Autor:
Xin-yu Qiao, Yi Wang, Wei Zhang, Qian Li, Chong Liu, Ji-ji Dao, Chen-meng Qiao, Chun Cui, Yan-qin Shen, Wei-jiang Zhao
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 4, p 96 (2023)
Objective: Few studies have reported the direct effect of C–X–C motif chemokine ligand 10 (CXCL10) and Neuregulin 1 (Nrg1) on neurons after spinal cord injury (SCI). This study reports the role of CXCL10 in the regulation of neuronal damage after
Externí odkaz:
https://doaj.org/article/457bfb7a80d64776844c23eb4bce8c8e
Publikováno v:
Folia Neuropathologica, Vol 59, Iss 2, Pp 189-197 (2021)
Externí odkaz:
https://doaj.org/article/c9630c8145f64b53aeda1aaaba0f4b26
Autor:
Wei Quan, Chen-Meng Qiao, Gu-Yu Niu, Jian Wu, Li-Ping Zhao, Chun Cui, Wei-Jiang Zhao, Yan-Qin Shen
Publikováno v:
Brain Sciences, Vol 13, Iss 5, p 790 (2023)
Observational studies have shown abnormal changes in trimethylamine N-oxide (TMAO) levels in the peripheral circulatory system of Parkinson’s disease (PD) patients. TMAO is a gut microbiota metabolite that can cross the blood–brain barrier and is
Externí odkaz:
https://doaj.org/article/960e3ffb27584aa4960d43ae4274541c
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundTransient receptor potential melastatin 8 (TRPM8) modulates tumor biology and sensitivity to treatment. The present study aimed to determine the part it plays in tumor immunity and physiology using pan-cancer analysis.MethodData from the GT
Externí odkaz:
https://doaj.org/article/a90d9dd09c184c3b9596d909f1b246e1
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 6, Pp 1058-1065 (2020)
Oxidative stress contributes to the pathogenesis of neurodegenerative diseases. With the aim to find reagents that reduce oxidative stress, a phage display library was screened for peptides mimicking α2,6-sialyllactose (6′-SL), which is known to b
Externí odkaz:
https://doaj.org/article/edf36ef6bba8464dbdc335f7a6a6adec