Zobrazeno 1 - 10
of 1 766
pro vyhledávání: '"WEEDON, A. P."'
Autor:
Douglas I. Kelley, France Gerard, Ning Dong, Chantelle Burton, Arthur Argles, Guangqi Li, Rhys Whitley, Toby R. Marthews, Eddy Roberston, Graham P. Weedon, Gitta Lasslop, Richard J. Ellis, Ioannis Bistinas, Elmar Veenendaal
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-15 (2024)
Abstract Explaining tropical tree cover distribution in areas of intermediate rainfall is challenging, with fire’s role in limiting tree cover particularly controversial. We use a novel Bayesian approach to provide observational constraints on the
Externí odkaz:
https://doaj.org/article/614fa8f2f3d14ceaaaed5cb1491bf695
Autor:
Gareth Hawkes, Robin N. Beaumont, Zilin Li, Ravi Mandla, Xihao Li, Christine M. Albert, Donna K. Arnett, Allison E. Ashley-Koch, Aneel A. Ashrani, Kathleen C. Barnes, Eric Boerwinkle, Jennifer A. Brody, April P. Carson, Nathalie Chami, Yii-Der Ida Chen, Mina K. Chung, Joanne E. Curran, Dawood Darbar, Patrick T. Ellinor, Myrian Fornage, Victor R. Gordeuk, Xiuqing Guo, Jiang He, Chii-Min Hwu, Rita R. Kalyani, Robert Kaplan, Sharon L. R. Kardia, Charles Kooperberg, Ruth J. F. Loos, Steven A. Lubitz, Ryan L. Minster, Take Naseri, Satupa’itea Viali, Braxton D. Mitchell, Joanne M. Murabito, Nicholette D. Palmer, Bruce M. Psaty, Susan Redline, M. Benjamin Shoemaker, Edwin K. Silverman, Marilyn J. Telen, Scott T. Weiss, Lisa R. Yanek, Hufeng Zhou, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Ching-Ti Liu, Kari E. North, Anne E. Justice, Jonathan M. Locke, Nick Owens, Anna Murray, Kashyap Patel, Timothy M. Frayling, Caroline F. Wright, Andrew R. Wood, Xihong Lin, Alisa Manning, Michael N. Weedon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The role of rare non-coding variation in complex human phenotypes is still largely unknown. To elucidate the impact of rare variants in regulatory elements, we performed a whole-genome sequencing association analysis for height using 333,100
Externí odkaz:
https://doaj.org/article/b2e3a91ecb614324b7f2fdd7370d5155
Autor:
Yan-Ci Liu, Patrick Esser, Benjamin David Weedon, Daniella Springett, Shawn Joshi, Meng-Hsuan Tsou, Ray-Yau Wang, Helen Dawes
Publikováno v:
Italian Journal of Pediatrics, Vol 50, Iss 1, Pp 1-9 (2024)
Abstract Background Motor competence (MC) is a key component reflecting one’s ability to execute motor tasks and is an important predictor of physical fitness. For adolescents, understanding the factors affecting MC is pertinent to their developmen
Externí odkaz:
https://doaj.org/article/3810aca87c774148857ee564cca5a6b3
Autor:
Junxi Liu, Rebecca C. Richmond, Emma L. Anderson, Jack Bowden, Ciarrah-Jane S. Barry, Hassan S. Dashti, Iyas S. Daghlas, Jacqueline M. Lane, Simon D. Kyle, Céline Vetter, Claire L. Morrison, Samuel E. Jones, Andrew R. Wood, Timothy M. Frayling, Alison K. Wright, Matthew J. Carr, Simon G. Anderson, Richard A. Emsley, David W. Ray, Michael N. Weedon, Richa Saxena, Martin K. Rutter, Deborah A. Lawlor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Self-reported shorter/longer sleep duration, insomnia, and evening preference are associated with hyperglycaemia in observational analyses, with similar observations in small studies using accelerometer-derived sleep traits. Mendelian random
Externí odkaz:
https://doaj.org/article/7570bd5e2c7049fda1219de8ef4b9840
Autor:
Malin Klein, Corentin Bisot, Loreto Oyarte Gálvez, Vasilis Kokkoris, Thomas S. Shimizu, Lemeng Dong, James T. Weedon, Harro Bouwmeester, E. Toby Kiers
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Strigolactones are phytohormones that influence arbuscular mycorrhizal fungal (AMF) spore germination, pre-symbiotic hyphal branching, and metabolic rates. Historically, strigolactone effects have been tested on single AMF strains. An open question i
Externí odkaz:
https://doaj.org/article/0287fee9b7bd460aabeed8d9aefe6d48
Autor:
Pavel Loginovic, Feiyi Wang, Jiang Li, Lauric Ferrat, Uyenlinh L. Mirshahi, H. Shanker Rao, Axel Petzold, Jessica Tyrrell, Harry D. Green, Michael N. Weedon, Andrea Ganna, Tiinamaija Tuomi, David J. Carey, UKBB Eye & Vision Consortium, FinnGen, Geisinger-Regeneron DiscovEHR Collaboration, Richard A. Oram, Tasanee Braithwaite
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Optic neuritis (ON) is associated with numerous immune-mediated inflammatory diseases, but 50% patients are ultimately diagnosed with multiple sclerosis (MS). Differentiating MS-ON from non-MS-ON acutely is challenging but important; non-MS
Externí odkaz:
https://doaj.org/article/f6426afe6a114af2b693c61ff64bdbc0
Autor:
Emad Al-Yahya, Patrick Esser, Benjamin D. Weedon, Shawn Joshi, Yan-Ci Liu, Daniella N. Springett, Piergiorgio Salvan, Andy Meaney, Johnny Collett, Mario Inacio, Anne Delextrat, Steve Kemp, Tomas Ward, Hooshang Izadi, Heidi Johansen-Berg, Hasan Ayaz, Helen Dawes
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/5a347b899c60419991ee04f62989403b
Autor:
Shahab Haghayegh, Chenlu Gao, Elizabeth Sugg, Xi Zheng, Hui-Wen Yang, Richa Saxena, Martin K Rutter, Michael Weedon, Agustin Ibanez, David A Bennett, Peng Li, Lei Gao, Kun Hu
Publikováno v:
JMIR Public Health and Surveillance, Vol 10, p e55211 (2024)
BackgroundThe relationship between 24-hour rest-activity rhythms (RARs) and risk for dementia or mild cognitive impairment (MCI) remains an area of growing interest. Previous studies were often limited by small sample sizes, short follow-ups, and old
Externí odkaz:
https://doaj.org/article/37653ac8ee8d4d06bedf53b545a7bb13
Autor:
Rebecca C. Richmond, Laurence J. Howe, Karl Heilbron, Samuel Jones, Junxi Liu, andMe Research Team, Xin Wang, Michael N. Weedon, Martin K. Rutter, Deborah A. Lawlor, George Davey Smith, Céline Vetter
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Spouses may affect each other’s sleeping behaviour. In 47,420 spouse-pairs from the UK Biobank, we found a weak positive phenotypic correlation between spouses for self-reported sleep duration (r = 0.11; 95% CI = 0.10, 0.12) and a weak inv
Externí odkaz:
https://doaj.org/article/0d6afd73158a41388c6fdaaca120cd03
Autor:
Katherine S. Ruth, Robin N. Beaumont, Jonathan M. Locke, Jessica Tyrrell, Carolyn J. Crandall, Gareth Hawkes, Timothy M. Frayling, Julia K. Prague, Kashyap A. Patel, Andrew R. Wood, Michael N. Weedon, Anna Murray
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract Background Vasomotor symptoms (VMS) can often significantly impact women’s quality of life at menopause. In vivo studies have shown that increased neurokinin B (NKB) / neurokinin 3 receptor (NK3R) signalling contributes to VMS, with previo
Externí odkaz:
https://doaj.org/article/145ca60b899e4205aab6ed58c64c7ff5