Zobrazeno 1 - 10
of 37
pro vyhledávání: '"WB, Western Blotting"'
Autor:
Fumio Sakane, Fumi Hoshino
Publikováno v:
Biochemical and Biophysical Research Communications
The clathrin coat assembly protein AP180 drives endocytosis, which is crucial for numerous physiological events, such as the internalization and recycling of receptors, uptake of neurotransmitters and entry of viruses, including SARS-CoV-2, by intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486bafc8e128e9f14b907481315a7d43
https://doi.org/10.1016/j.bbrc.2021.11.097
https://doi.org/10.1016/j.bbrc.2021.11.097
Autor:
Jamil Yousef, Malin Jönsson, My Hedhammar, Sara Mravinacova, Anna Månberg, Peter Nilsson, Elisa Pin, Sebastian Havervall, Sophia Hober, Jonas Klingström, Wanda Christ, Cecilia Hellström, Charlotte Thålin, Hanna Tegel
Publikováno v:
New Biotechnology
Highly accurate serological tests are key to assessing the prevalence of SARS-CoV-2 antibodies and the level of immunity in the population. This is important to predict the current and future status of the pandemic. With the recent emergence of new a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c71cea41044b86ad4ad6481d104d28b
http://europepmc.org/articles/PMC8495044
http://europepmc.org/articles/PMC8495044
Autor:
Hui Liu, Sara Maimouni, Sara Coppola, Ye Zhang, Jianliang Shen, Yijun Wang, Shenglan Gao, Ying-Tang Gao, Fengmei Wang, Heineken Queen Daguplo, Wei-Xing Zong, Junrong Yan, Zhi Du, Fang Wang, Yongbo Wang, Peng Wang, Bin Yang, Qin Zhang, Grace L. Guo, Kesong Peng, Wen-Xing Ding, Weiwei Dai, Fei Tang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1369-1385 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1369-1385 (2021)
Background and Aims TRIM21 is a ubiquitin E3 ligase that is implicated in numerous biological processes including immune response, cell metabolism, redox homeostasis, and cancer development. We recently reported that TRIM21 can negatively regulate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f585b89cd7f24b7e5100047070b705c
https://doi.org/10.1016/j.jcmgh.2021.01.007
https://doi.org/10.1016/j.jcmgh.2021.01.007
Autor:
Yi-Chao Zheng, Hong-Min Liu, Ouwen Li, Jun-Wei Wang, Zhenhe Suo, Fengyu Qi, Wen-Ting Kang, Pengxing He, Zhi-Ru Wang, Yinghua You
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 694-707 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 694-707 (2021)
Targeting immune checkpoints such as programmed cell death protein 1 (PD-1) and programmed death ligand-1 (PD-L1) have been approved for treating melanoma, gastric cancer (GC) and bladder cancer with clinical benefit. Nevertheless, many patients fail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3f6e9de03bb3ad460a61d5471e4bca
http://europepmc.org/articles/PMC7982505
http://europepmc.org/articles/PMC7982505
Transduction of modified factor VIII gene improves lentiviral gene therapy efficacy for hemophilia A
Publikováno v:
The Journal of Biological Chemistry
Hemophilia A (HA) is a bleeding disorder caused by deficiency of the coagulation factor VIII (F8). F8 replacement is standard of care, whereas gene therapy (F8 gene) for HA is an attractive investigational approach. However, the large size of the F8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab495a45316d16a342f81c5efa023625
https://doi.org/10.1016/j.jbc.2021.101397
https://doi.org/10.1016/j.jbc.2021.101397
Autor:
Anita Huttner, Stephen M. Strittmatter, Alison Chase, Charlotte Herber, Sarah Helena Nies, Hideyuki Takahashi
Publikováno v:
The Journal of Biological Chemistry
In Alzheimer's disease (AD), deposition of pathological tau and amyloid-β (Aβ) drive synaptic loss and cognitive decline. The injection of misfolded tau aggregates extracted from human AD brains drives templated spreading of tau pathology within WT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a4ef2dad966a0ccb1a001c52a6c6b9
https://doi.org/10.1016/j.jbc.2021.101159
https://doi.org/10.1016/j.jbc.2021.101159
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 438-455 (2017)
Redox Biology
Redox Biology
Resolvins are a novel class of lipid mediators that play an important role in the resolution of inflammation, although the underlying mechanisms are not very clear. To explore the anti-inflammatory mechanisms of resolvins, we have studied the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2456946e21afa8586484a8732cb972ef
http://www.sciencedirect.com/science/article/pii/S2213231717300642
http://www.sciencedirect.com/science/article/pii/S2213231717300642
Publikováno v:
EBioMedicine
EBioMedicine, Vol 15, Iss C, Pp 62-72 (2017)
EBioMedicine, Vol 15, Iss C, Pp 62-72 (2017)
Clear cell renal cell carcinoma (ccRCC) is the most lethal neoplasm of the urologic system. Clinical therapeutic effect varies greatly between individual ccRCC patients, so there is an urgent need to develop prognostic molecular biomarkers to help cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8f64b5502a35e2b61a2a5b14ba4d22
https://doi.org/10.1016/j.ebiom.2016.12.003
https://doi.org/10.1016/j.ebiom.2016.12.003
Autor:
Takamichi Sato, Kazuhiro Tokunaka, Arihiro Tomura, Kan Saiga, Hidemitsu Sugihara, Makoto Morita, Yasutada Imamura, Toshihiko Hayashi
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 128-132 (2017)
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 128-132 (2017)
This report describes the preparation and partial characterization of monoclonal antibodies that are reactive specifically with the nascently produced non-triple helical form of the type IV collagen α1 chain, designated as NTH α1(IV). These antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3d4710ca1a571a3baf964e3aee6558
http://europepmc.org/articles/PMC5614550
http://europepmc.org/articles/PMC5614550
Autor:
Roberto Simone, Yun-Ru Chen, Claire Troakes, Jia Newcombe, Rickie Patani, Phillip Smethurst, Katie Sidle
Publikováno v:
Neurobiology of Disease, Vol 96, Iss, Pp 236-247 (2016)
Smethurst, P, Newcombe, J, Troakes, C, Simone, R, Chen, Y-R, Patani, R & Sidle, K 2016, ' In vitro prion-like behaviour of TDP-43 in ALS ', Neurobiology of Disease . https://doi.org/10.1016/j.nbd.2016.08.007
Neurobiology of Disease
Smethurst, P, Newcombe, J, Troakes, C, Simone, R, Chen, Y-R, Patani, R & Sidle, K 2016, ' In vitro prion-like behaviour of TDP-43 in ALS ', Neurobiology of Disease . https://doi.org/10.1016/j.nbd.2016.08.007
Neurobiology of Disease
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease (MND), and > 95% of familial and sporadic cases involve the deposition of insoluble aggregated, phosphorylated and cleaved TDP-43 protein. Accumulating clinical and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b4b5ad9cf546a7b3468cf5b9663216
http://www.sciencedirect.com/science/article/pii/S0969996116301954
http://www.sciencedirect.com/science/article/pii/S0969996116301954