Zobrazeno 1 - 10
of 205
pro vyhledávání: '"WAYNE D. COMPER"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The fractional clearance of proteins as measured in healthy human subjects increases 10,000–100,000- fold when studied in nephrotic patients. This remarkable increase cannot be accounted for by extracellular biophysical mechanisms centered at the g
Externí odkaz:
https://doaj.org/article/cba16c62a9e6405eaec6f713c466364f
Autor:
Wayne D. Comper
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/ea8354925fed4a9f8a3f88bc9cf65349
Autor:
Xiaomin Song, Louis J. Imbriano, Rajanandini Muralidharan, Leileata M. Russo, Aaron Pinkhasov, John K. Maesaka, Wayne D. Comper
Publikováno v:
The American Journal of the Medical Sciences. 361:261-268
Background The most vexing problem in hyponatremic conditions is to differentiate the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) from cerebral/renal salt wasting (C-RSW). Both have identical clinical parameters but diametrica
Autor:
Piruz Motamedinia, Anna N Scott, Kendall L Bate, Neda Sadeghi, Guillermo Salazar, Edan Shapiro, Jennifer Ahn, Michael Lipsky, James Lin, Greg W Hruby, Ketan K Badani, Daniel P Petrylak, Mitchell C Benson, Michael J Donovan, Wayne D Comper, James M McKiernan, Leileata M Russo
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154507 (2016)
PURPOSE:The analysis of exosome/microvesicle (extracellular vesicles (EVs)) and the RNA packaged within them (exoRNA) has the potential to provide a non-invasive platform to detect and monitor disease related gene expression potentially in lieu of mo
Externí odkaz:
https://doaj.org/article/f706f9925db946debb4c99baef33899f
Autor:
Julijana Vuchkova, Wayne D Comper
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127853 (2015)
Inhibition of the degradation of filtered albumin has been proposed as a widespread, benign form of albuminuria. There have however been recent reports that radiolabeled albumin fragments in urine are not exclusively generated by the kidney and that
Externí odkaz:
https://doaj.org/article/c203419978454968a65b5d4c3d52f9c3
Autor:
Wayne D. Comper
Publikováno v:
Kidney International
Publikováno v:
Journal of Theoretical Biology. 410:18-24
In order to understand the mechanism of albuminuria we have explored how other plasma proteins are processed by the kidney as compared to inert molecules like Ficolls. When fractional clearances are plotted versus protein radius there is a remarkable
Publikováno v:
American Journal of Physiology-Renal Physiology. 307:F525-F532
Albuminuria in nephrotic states is thought to arise from the formation of large pores in the glomerular capillary wall as large hydrodynamic probes, like Ficoll, have increased fractional clearance. In the present study, we tested for large pore form
Autor:
Wayne D. Comper
Publikováno v:
Kidney International. 94:219-220
Autor:
Wayne D. Comper
Publikováno v:
Kidney International. 93:1014