Zobrazeno 1 - 10
of 45
pro vyhledávání: '"WALTER N. PIPER"'
Autor:
Lorelle L. Bestervelt, Jeff A. Pitt, Colleen J. Nolan, Y. Cai, Douglas W. Piper, Joseph A. Dybowski, Gerald A. Dayharsh, Walter N. Piper
Publikováno v:
Toxicological Sciences. 44:107-115
Publikováno v:
Toxicological Sciences. 46:294-299
Publikováno v:
Toxicology Letters. 70:139-145
This study was performed to determine whether TCDD (50 μg kg ; single oral dose) could induce adrenal microsomal lipid peroxidation, which might be correlated to decreased levels of cytochrome P-450 and 21-hydroxylase activity. The amount of malondi
Autor:
Walter N. Piper, Douglas W. Piper, Yong Cai, Jeff A. Pitt, Colleen J. Nolan, Lorelle L. Bestervelt
Publikováno v:
Neurotoxicology and Teratology. 15:365-370
Plasma ACTH concentrations in 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats (50 micrograms/kg; single, oral dose) were 2.1-, 2.1-, 2.9-, 1.7-, 1.5-, 2.0- and 3.0-fold greater than control values, respectively, at days 1, 3, 5, 7, 10, and
Publikováno v:
Neurotoxicology and Teratology. 15:371-376
The present study assessed the ability of primary cultures of rat anterior pituitary cells to secrete bioactive ACTH in the presence of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). The bioactivity of the secreted pituitary cell ACTH was determined
Autor:
Walter N. Piper, Katarina T. Borer, Mary Beth Brosamer, Uma Swamy, Michal Mannheim, Melva Thompson, Lorelle L. Bestervelt
Publikováno v:
Physiology & Behavior. 51:713-718
The possibility that habitual voluntary running induces a chronic change in adrenal glucocorticoid synthesis and secretion was examined in freely running mature female hamsters, in whom this behavior accelerates growth, reduces body fat levels, and e
Publikováno v:
Biology of Reproduction. 45:143-150
It is known that administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes decreased serum testosterone concentrations in the rat. Previous studies in this laboratory have shown that in rats TCDD exposure results in decreased 17 alpha-hydro
Autor:
Warren W. Ku, Walter N. Piper
Publikováno v:
Toxicology Letters. 51:91-97
The role of nutritional factors on heme synthesis and their influence on the development of anemia in the bone marrow during lead exposure is unclear. Previous reports suggested that pteridines could regulate the formation of uroporphyrinogen, a step
Autor:
Walter N. Piper, Lorelle L. Bestervelt, C Shorter, Donald G. Patterson, Larry L. Needham, Colleen J. Nolan, George W. Lucier, ES Johnson
Publikováno v:
Toxicology and industrial health. 17(4)
We measured current serum hormone and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) concentrations in 37 men who sprayed 2,4,5- trichlorophenoxyacetic acid (2,4,5-T) in the State of Victoria, Australia. TCDD levels were consistently significantly invers
Autor:
Lorelle L. Bestervelt, Carol Mousigian, Colleen J. Nolan, Phaitoon Maimansomsuk, Yong Cai, Walter N. Piper
Publikováno v:
Neurotoxicology and Teratology. 13:495-497
The present study was undertaken to assess if hypothalamic beta-endorphin (beta E) and/or brain mu opioid receptors are associated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) (50 micrograms/kg)-induced hypophagia and body weight decline in rat