Zobrazeno 1 - 10
of 334
pro vyhledávání: '"WALTER F. BORON"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Metabolic acidosis (MAc)—an extracellular pH (pHo) decrease caused by a [HCO3−]o decrease at constant [CO2]o—usually causes intracellular pH (pHi) to fall. Here we determine the extent to which the pHi decrease depends on the pHo decrease vs th
Externí odkaz:
https://doaj.org/article/2a62928045b4444992ceda97ed66d00a
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Receptor protein tyrosine phosphatases γ and ζ (RPTPγ and RPTPζ) are transmembrane signaling proteins with extracellular carbonic anhydrase–like domains that play vital roles in the development and functioning of the central nervous system (CNS
Externí odkaz:
https://doaj.org/article/c7099af346c64257bbab8dcab02fcf6b
Autor:
Lu Cai, Dengke Wang, Tianxiang Gui, Xiaoyu Wang, Lingyu Zhao, Walter F. Boron, Li-Ming Chen, Ying Liu
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The kidney plays a central role in maintaining the fluid and electrolyte homeostasis in the body. Bicarbonate transporters NBCn1, NBCn2, and AE2 are expressed at the basolateral membrane of the medullary thick ascending limb (mTAL). In a previous stu
Externí odkaz:
https://doaj.org/article/16a991f7db2b4c3c82bb5c9291630f1b
Autor:
Fraser J. Moss, Paween Mahinthichaichan, David T. Lodowski, Thomas Kowatz, Emad Tajkhorshid, Andreas Engel, Walter F. Boron, Ardeschir Vahedi-Faridi
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Xenopus oocytes expressing human aquaporin-7 (AQP7) exhibit greater osmotic water permeability and 3H-glycerol uptake vs. those expressing the bacterial glycerol facilitator GlpF. AQP7-expressing oocytes exposed to increasing extracellular [glycerol]
Externí odkaz:
https://doaj.org/article/35f03b2c1ad74f409cf1ec7994cffeba
Autor:
Jin-Lin Wang, Lei Zhao, Jun Zhu, Deng-Ke Wang, Mei-Juan Ren, Meng Wang, Ying Liu, Walter F. Boron, Li-Ming Chen
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The electroneutral Na+/HCO3– cotransporter NBCn2 (SLC4A10) of solute carrier family 4 (SLC4) plays important physiological and pathological roles in the body. Our previous study showed that NBCn2 is expressed on the protein level in the small intes
Externí odkaz:
https://doaj.org/article/61a76e55a97042af98227c6a2e2cdddf
Publikováno v:
Sensors, Vol 13, Iss 1, Pp 984-1003 (2013)
Determining the effective concentration (i.e., activity) of ions in and around living cells is important to our understanding of the contribution of those ions to cellular function. Moreover, monitoring changes in ion activities in and around cells i
Externí odkaz:
https://doaj.org/article/2d6259ae3cef4220b4495a27367ddbe5
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Intracellular pH (pHi) regulation in the brain is important in both physiological and physiopathological conditions because changes in pHi generally result in altered neuronal excitability. In this review, we will cover 4 major areas: [1] The effect
Externí odkaz:
https://doaj.org/article/d72fad96fda44c0fa51b23bc05aa83ab
Autor:
Seong-Ki Lee, Rossana Occhipinti, Fraser J. Moss, Mark D. Parker, Irina I. Grichtchenko, Walter F. Boron
Publikováno v:
Journal of the American Society of Nephrology. 34:40-54
Autor:
Yifan Zhang, Kui Xu, Yuchi Liu, Bernadette O Erokwu, Pan Zhao, Chris A Flask, Ciro Ramos-Estebanez, George W Farr, Joseph C LaManna, Walter F Boron, Xin Yu
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218415 (2019)
Aquaporin-4 (AQP4) plays an important role in regulating water exchange across the blood-brain barrier (BBB) and brain-cerebrospinal fluid interface. Studies on AQP-4 knockout mice (AQP4-KO) have reported considerable protection from brain edema indu
Externí odkaz:
https://doaj.org/article/affea4c584254db5b83283ed24ecdffe
Postnatal Exposure to Brief Hypoxia Alters Brain VEGF Expression and Capillary Density in Adult Mice
Autor:
Michael B, Komarovsky, Constantinos P, Tsipis, Khalil A, Almotah, Walter F, Boron, Kui, Xu, Joseph, LaManna
Publikováno v:
Advances in experimental medicine and biology. 1395
Perinatal hypoxia leads to changes in cerebral angiogenesis and persistent structural and functional changes in the adult brain. It may also result in greater vulnerability to subsequent challenges. We investigated the effect of postnatal day 2 (P2)